| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flumatinib (mesylate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flumatinib (mesylate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.295818 |
| VIM | vimentin | 0.162451 |
| FAM13A | family with sequence similarity 13, member A | 0.137339 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0997502 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0834452 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.078988 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0757627 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0702396 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0687427 |
| NAV2 | neuron navigator 2 | 0.0658979 |
| SPAG9 | sperm associated antigen 9 | 0.0650301 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0648963 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0648144 |
| INHBA | inhibin, beta A | 0.0633418 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0626106 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0608561 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0576691 |
| FMNL2 | formin-like 2 | 0.0571421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0547324 |
| CD44 | CD44 molecule (Indian blood group) | 0.0521542 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0514155 |
| RPS12 | ribosomal protein S12 | 0.0511531 |
| RPL4 | ribosomal protein L4 | 0.0502695 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0490003 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0484775 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0481502 |
| ATP13A3 | ATPase type 13A3 | 0.0472723 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0464103 |
| ASPH | aspartate beta-hydroxylase | 0.0459699 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.045637 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0454663 |
| NUP58 | nucleoporin 58 | 0.0441389 |
| DST | dystonin | 0.0435451 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0433909 |
| PGK1 | phosphoglycerate kinase 1 | 0.0428642 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0422171 |
| PRELID2 | PRELI domain containing 2 | 0.0408785 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.040488 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0403639 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0402817 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0398411 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.039513 |
| PTMA | prothymosin, alpha | 0.0393645 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0391032 |
| STC1 | stanniocalcin 1 | 0.0388962 |
| RPL3 | ribosomal protein L3 | 0.0378595 |
| TPM3 | tropomyosin 3 | 0.0375151 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0371499 |
| FNIP1 | folliculin interacting protein 1 | 0.0371328 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0369293 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.036899 |
| HMGB2 | high mobility group box 2 | 0.0366572 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0365554 |
| SET | SET nuclear proto-oncogene | 0.036003 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0354554 |
| NBAS | neuroblastoma amplified sequence | 0.035328 |
| YEATS2 | YEATS domain containing 2 | 0.0351815 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0351143 |
| GOLGA4 | golgin A4 | 0.0341446 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0340758 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0339197 |
| LDHA | lactate dehydrogenase A | 0.0335083 |
| CDK19 | cyclin-dependent kinase 19 | 0.0332765 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0323938 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0323319 |
| CALU | calumenin | 0.0322324 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0320274 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0318374 |
| KIF5B | kinesin family member 5B | 0.0314053 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0313859 |
| APP | amyloid beta (A4) precursor protein | 0.0307667 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0303768 |
| CENPF | centromere protein F, 350/400kDa | 0.0302371 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0296492 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0295586 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0293993 |
| SEPTIN9 | septin 9 | 0.0293104 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0292413 |
| MEIS1 | Meis homeobox 1 | 0.0290299 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0289158 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0286878 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0285796 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285046 |
| CALR | calreticulin | 0.0284712 |
| MSN | moesin | 0.0281593 |
| TMF1 | TATA element modulatory factor 1 | 0.0281516 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279339 |
| COPA | coatomer protein complex, subunit alpha | 0.0279082 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0278928 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0278159 |
| GPHN | gephyrin | 0.027328 |
| SUCO | SUN domain containing ossification factor | 0.0270117 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0268148 |
| TNS1 | tensin 1 | 0.0266551 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0266099 |
| ZNF292 | zinc finger protein 292 | 0.026353 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0262916 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260741 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0258699 |
| RPL37A | ribosomal protein L37a | 0.0258197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.549748 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115442 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0941578 |
| FTL | ferritin, light polypeptide | -0.0924065 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0832026 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0744562 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0515942 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0445401 |
| EMP1 | epithelial membrane protein 1 | -0.0427436 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0417954 |
| FBN1 | fibrillin 1 | -0.040543 |
| TMSB10 | thymosin beta 10 | -0.0392175 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0338141 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0333439 |
| EGR1 | early growth response 1 | -0.0328722 |
| RPLP1 | ribosomal protein, large, P1 | -0.0327455 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.032376 |
| COL1A1 | collagen, type I, alpha 1 | -0.0323649 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0316008 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0307062 |
| TXNIP | thioredoxin interacting protein | -0.0306634 |
| IER3 | immediate early response 3 | -0.0287408 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0281826 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0273703 |
| CLMP | CXADR-like membrane protein | -0.0270954 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0265421 |
| UBC | ubiquitin C | -0.0257278 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0256138 |
| HMGA2 | high mobility group AT-hook 2 | -0.0254053 |
| H1-0 | H1.0 linker histone | -0.0251519 |
| CALD1 | caldesmon 1 | -0.0250497 |
| MAP1B | microtubule-associated protein 1B | -0.0249651 |
| COL5A3 | collagen, type V, alpha 3 | -0.0247647 |
| RPL28 | ribosomal protein L28 | -0.0243818 |
| VCL | vinculin | -0.0243025 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.024183 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0241105 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0240476 |
| SEPTIN11 | septin 11 | -0.0240033 |
| PRRX1 | paired related homeobox 1 | -0.023842 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0235425 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0230902 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225952 |
| AHNAK | AHNAK nucleoprotein | -0.0225396 |
| RPS6 | ribosomal protein S6 | -0.022298 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0222874 |
| FOXP1 | forkhead box P1 | -0.022275 |
| RASAL2 | RAS protein activator like 2 | -0.0221451 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0221399 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0218021 |
| RAI14 | retinoic acid induced 14 | -0.0215324 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0214362 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0211569 |
| NABP1 | nucleic acid binding protein 1 | -0.020431 |
| BSG | basigin (Ok blood group) | -0.0203858 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0200108 |
| MMP1 | matrix metallopeptidase 1 | -0.0196068 |
| RND3 | Rho family GTPase 3 | -0.019585 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0195004 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0191276 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0190719 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0186653 |
| RPS19 | ribosomal protein S19 | -0.0185268 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0183138 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0181496 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0181315 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.017943 |
| RPL8 | ribosomal protein L8 | -0.0178235 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0177721 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0175759 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0173109 |
| LYST | lysosomal trafficking regulator | -0.017305 |
| FRMD4A | FERM domain containing 4A | -0.0172541 |
| OSMR | oncostatin M receptor | -0.0170927 |
| YBX3 | Y box binding protein 3 | -0.0169847 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0168997 |
| H3-3B | H3.3 histone B | -0.0168444 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.016826 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0168086 |
| OXR1 | oxidation resistance 1 | -0.0166703 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0166502 |
| NOTCH3 | notch 3 | -0.0166431 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0165197 |
| HHIP | hedgehog interacting protein | -0.0162615 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.016261 |
| CCDC102B | coiled-coil domain containing 102B | -0.0162269 |
| TAOK3 | TAO kinase 3 | -0.0162076 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0161321 |
| S100A9 | S100 calcium binding protein A9 | -0.0160602 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0160173 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0158183 |
| PFN1 | profilin 1 | -0.0155533 |
| RPL35 | ribosomal protein L35 | -0.0154763 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0154036 |
| FUS | FUS RNA binding protein | -0.0153445 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0152735 |
| ZNF804A | zinc finger protein 804A | -0.0152077 |
| GLG1 | golgi glycoprotein 1 | -0.0151622 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0151267 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0151214 |
