| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/16850 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Fluorescein relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| H3C1 | H3 clustered histone 1 | 0.82 |
| UFC1 | ubiquitin-fold modifier conjugating enzyme 1 | 0.65 |
| SP100 | SP100 nuclear antigen | 0.64 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.61 |
| TMEM183B | transmembrane protein 183B | 0.56 |
| HDAC7 | histone deacetylase 7 | 0.52 |
| SCAND1 | SCAN domain containing 1 | 0.52 |
| ENKD1 | enkurin domain containing 1 | 0.47 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.45 |
| ZNF395 | zinc finger protein 395 | 0.44 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.44 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | 0.43 |
| TDG | thymine-DNA glycosylase | 0.42 |
| MIER2 | mesoderm induction early response 1, family member 2 | 0.41 |
| RHOA | ras homolog family member A | 0.41 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | 0.39 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.39 |
| ANKRD39 | ankyrin repeat domain 39 | 0.38 |
| RAD51C | RAD51 paralog C | 0.37 |
| RND3 | Rho family GTPase 3 | 0.35 |
| ATXN1 | ataxin 1 | 0.34 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.34 |
| SFXN5 | sideroflexin 5 | 0.34 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.33 |
| UBE2N | ubiquitin-conjugating enzyme E2N | 0.32 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 0.32 |
| TVP23C | trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) | 0.32 |
| FBXO34 | F-box protein 34 | 0.32 |
| PRR3 | proline rich 3 | 0.32 |
| ZNF611 | zinc finger protein 611 | 0.32 |
| PRXL2C | peroxiredoxin like 2C | 0.32 |
| USP19 | ubiquitin specific peptidase 19 | 0.31 |
| ZNF354B | zinc finger protein 354B | 0.31 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.31 |
| DCK | deoxycytidine kinase | 0.31 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | 0.3 |
| PER2 | period circadian clock 2 | 0.3 |
| CIAO2B | cytosolic iron-sulfur assembly component 2B | 0.29 |
| PPP1R2B | PPP1R2 family member B | 0.29 |
| SPECC1 | sperm antigen with calponin homology and coiled-coil domains 1 | 0.29 |
| PLEKHN1 | pleckstrin homology domain containing, family N member 1 | 0.29 |
| SLC66A2 | solute carrier family 66 member 2 | 0.29 |
| GPSM2 | G-protein signaling modulator 2 | 0.29 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.29 |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 0.28 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.28 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.28 |
| SMIM12 | small integral membrane protein 12 | 0.28 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.28 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.28 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.28 |
| PUM1 | pumilio RNA-binding family member 1 | 0.28 |
| CBX3 | chromobox homolog 3 | 0.27 |
| ZNF428 | zinc finger protein 428 | 0.27 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.27 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.27 |
| CDON | cell adhesion associated, oncogene regulated | 0.27 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | 0.27 |
| PCBP3 | poly(rC) binding protein 3 | 0.26 |
| TMEM106C | transmembrane protein 106C | 0.26 |
| CUEDC1 | CUE domain containing 1 | 0.26 |
| OBSL1 | obscurin-like 1 | 0.26 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.26 |
| TRIM65 | tripartite motif containing 65 | 0.26 |
| SERF2 | small EDRK-rich factor 2 | 0.26 |
| ZKSCAN2 | zinc finger with KRAB and SCAN domains 2 | 0.26 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.26 |
| NEMP2 | nuclear envelope integral membrane protein 2 | 0.25 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.25 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.25 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.25 |
| RPL30 | ribosomal protein L30 | 0.25 |
| JMJD4 | jumonji domain containing 4 | 0.25 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.25 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.25 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.25 |
| MACC1 | metastasis associated in colon cancer 1 | 0.25 |
| BOLA1 | bolA family member 1 | 0.25 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.24 |
| MAGEE1 | melanoma antigen family E1 | 0.24 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) | 0.24 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 0.24 |
| N4BP3 | NEDD4 binding protein 3 | 0.24 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.24 |
| TPM2 | tropomyosin 2 (beta) | 0.24 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.24 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.24 |
| METTL4 | methyltransferase like 4 | 0.24 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | 0.24 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.24 |
| SYN1 | synapsin I | 0.24 |
| UBQLN2 | ubiquilin 2 | 0.24 |
| EPN3 | epsin 3 | 0.24 |
| GTF3C6 | general transcription factor IIIC, polypeptide 6, alpha 35kDa | 0.23 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.23 |
| HMGXB3 | HMG box domain containing 3 | 0.23 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.23 |
| FRRS1 | ferric-chelate reductase 1 | 0.23 |
| FEM1A | fem-1 homolog a (C. elegans) | 0.23 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.23 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IRF9 | interferon regulatory factor 9 | -0.9 |
| TEN1 | TEN1 CST complex subunit | -0.75 |
| RGN | regucalcin | -0.72 |
| DAP | death-associated protein | -0.68 |
| PIP | prolactin-induced protein | -0.64 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.56 |
| RGPD2 | RANBP2-like and GRIP domain containing 2 | -0.54 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.54 |
| TMEM184A | transmembrane protein 184A | -0.54 |
| VGF | VGF nerve growth factor inducible | -0.53 |
| FGF19 | fibroblast growth factor 19 | -0.51 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.51 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.5 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.48 |
| SOD1 | superoxide dismutase 1, soluble | -0.48 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -0.46 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.44 |
| ZSWIM7 | zinc finger, SWIM-type containing 7 | -0.44 |
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | -0.43 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 | -0.43 |
| FAM110C | family with sequence similarity 110, member C | -0.43 |
| PYGM | phosphorylase, glycogen, muscle | -0.42 |
| HSPA8 | heat shock 70kDa protein 8 | -0.41 |
| SLC39A3 | solute carrier family 39 (zinc transporter), member 3 | -0.41 |
| FUT10 | fucosyltransferase 10 (alpha (1,3) fucosyltransferase) | -0.4 |
| RHOD | ras homolog family member D | -0.4 |
| MT-CO1 | cytochrome c oxidase subunit I | -0.4 |
| PRDM16 | PR domain containing 16 | -0.39 |
| FN1 | fibronectin 1 | -0.39 |
| HBA1 | hemoglobin, alpha 1 | -0.38 |
| ZNF484 | zinc finger protein 484 | -0.38 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.38 |
| TMEM219 | transmembrane protein 219 | -0.38 |
| TMEM59 | transmembrane protein 59 | -0.37 |
| MSANTD4 | Myb/SANT-like DNA-binding domain containing 4 with coiled-coils | -0.37 |
| KIAA1210 | KIAA1210 | -0.36 |
| VSIR | V-set immunoregulatory receptor | -0.35 |
| ARL14EPL | ADP-ribosylation factor-like 14 effector protein-like | -0.35 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -0.35 |
| EHD3 | EH-domain containing 3 | -0.35 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | -0.34 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.34 |
| ABHD3 | abhydrolase domain containing 3 | -0.34 |
| COL7A1 | collagen, type VII, alpha 1 | -0.34 |
| MBLAC2 | metallo-beta-lactamase domain containing 2 | -0.33 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.33 |
| NCKAP5L | NCK-associated protein 5-like | -0.32 |
| NRP1 | neuropilin 1 | -0.32 |
| SEC61B | Sec61 beta subunit | -0.32 |
| ITM2B | integral membrane protein 2B | -0.32 |
| ANAPC11 | anaphase promoting complex subunit 11 | -0.32 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.32 |
| ZNF184 | zinc finger protein 184 | -0.31 |
| FGA | fibrinogen alpha chain | -0.3 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.3 |
| SPPL2B | signal peptide peptidase like 2B | -0.29 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.29 |
| PTPDC1 | protein tyrosine phosphatase domain containing 1 | -0.29 |
| SLC22A18 | solute carrier family 22, member 18 | -0.29 |
| PLK4 | polo-like kinase 4 | -0.29 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.29 |
| ZNF776 | zinc finger protein 776 | -0.29 |
| APOE | apolipoprotein E | -0.28 |
| BLOC1S5 | biogenesis of lysosomal organelles complex-1, subunit 5, muted | -0.28 |
| MFSD14B | major facilitator superfamily domain containing 14B | -0.27 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | -0.27 |
| FHIT | fragile histidine triad | -0.27 |
| GJC1 | gap junction protein, gamma 1, 45kDa | -0.27 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.27 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.27 |
| HRH1 | histamine receptor H1 | -0.27 |
| RAB8B | RAB8B, member RAS oncogene family | -0.26 |
| CFAP410 | cilia and flagella associated protein 410 | -0.26 |
| NCOA4 | nuclear receptor coactivator 4 | -0.26 |
| SAMD8 | sterile alpha motif domain containing 8 | -0.26 |
| SELENOK | selenoprotein K | -0.26 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | -0.26 |
| RP9 | retinitis pigmentosa 9 (autosomal dominant) | -0.25 |
| SGCE | sarcoglycan, epsilon | -0.25 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.25 |
| SLC49A4 | solute carrier family 49 member 4 | -0.25 |
| RPL36A | ribosomal protein L36a | -0.25 |
| DNAH12 | dynein, axonemal, heavy chain 12 | -0.25 |
| ALS2CL | ALS2 C-terminal like | -0.25 |
| ZBTB49 | zinc finger and BTB domain containing 49 | -0.25 |
| STRIP2 | striatin interacting protein 2 | -0.25 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.25 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.25 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.25 |
| CEP85L | centrosomal protein 85kDa-like | -0.24 |
| MT1X | metallothionein 1X | -0.24 |
| ZBTB6 | zinc finger and BTB domain containing 6 | -0.24 |
| RWDD4 | RWD domain containing 4 | -0.24 |
| ARFGEF3 | ARFGEF family member 3 | -0.24 |
| AREG | amphiregulin | -0.24 |
| ITGA7 | integrin, alpha 7 | -0.24 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.23 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | -0.23 |
| ELMO1 | engulfment and cell motility 1 | -0.23 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.23 |
