Fluoro-SAHA Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

51 genes differentially expressed following the Fluoro-SAHA small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MT2A metallothionein 2A 5.86847
GCDH glutaryl-CoA dehydrogenase 4.80183
MT1X metallothionein 1X 4.64133
GPD1L glycerol-3-phosphate dehydrogenase 1-like 4.58815
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 3.77754
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 3.45932
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 3.41645
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 3.37155
TOR1B torsin family 1, member B (torsin B) 3.36768
MT1HL1 metallothionein 1H-like 1 3.33687
CFD complement factor D (adipsin) 3.31446
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 3.3122
AKAP12 A kinase (PRKA) anchor protein 12 3.29923
MT1H metallothionein 1H 3.28531
TKTL1 transketolase-like 1 3.25434
TATDN2 TatD DNase domain containing 2 3.24749
PLA2G15 phospholipase A2, group XV 3.22588
NOSIP nitric oxide synthase interacting protein 3.16542
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 3.16316
FADS3 fatty acid desaturase 3 3.15223
CCND3 cyclin D3 3.14497
ACAD8 acyl-CoA dehydrogenase family, member 8 3.13769
EXOC2 exocyst complex component 2 3.11883
OAT ornithine aminotransferase 3.09805
MPZL1 myelin protein zero-like 1 3.07704
LIMD2 LIM domain containing 2 3.04848
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 3.04111
ARHGAP29 Rho GTPase activating protein 29 3.03996
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.0379
COG5 component of oligomeric golgi complex 5 3.02688
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 3.02439

decreased expression

Symbol Name Standardized Value
ZNF710 zinc finger protein 710 -3.6743
KEAP1 kelch-like ECH-associated protein 1 -3.59321
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -3.50806
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -3.44882
PMF1 polyamine-modulated factor 1 -3.42469
ZNF141 zinc finger protein 141 -3.35215
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -3.21546
SENP6 SUMO1/sentrin specific peptidase 6 -3.21005
ZNF140 zinc finger protein 140 -3.15639
ZFP64 ZFP64 zinc finger protein -3.14168
CTPS2 CTP synthase 2 -3.14058
IKZF3 IKAROS family zinc finger 3 (Aiolos) -3.13598
MCM5 minichromosome maintenance complex component 5 -3.13075
OBSL1 obscurin-like 1 -3.097
NLRX1 NLR family member X1 -3.08023
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -3.06027
NBN nibrin -3.04361
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -3.01945
DPP3 dipeptidyl-peptidase 3 -3.01668
SPAG7 sperm associated antigen 7 -3.00881