Fluoropyrimidine activity Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP1601.html
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Genes

33 proteins participating in the Fluoropyrimidine activity pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
CDA cytidine deaminase
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DHFR dihydrofolate reductase
DPYD dihydropyrimidine dehydrogenase
DPYS dihydropyrimidinase
ERCC2 excision repair cross-complementation group 2
FPGS folylpolyglutamate synthase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
PPAT phosphoribosyl pyrophosphate amidotransferase
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
TDG thymine-DNA glycosylase
TK1 thymidine kinase 1, soluble
TP53 tumor protein p53
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UCK1 uridine-cytidine kinase 1
UCK2 uridine-cytidine kinase 2
UMPS uridine monophosphate synthetase
UPB1 ureidopropionase, beta
UPP1 uridine phosphorylase 1
UPP2 uridine phosphorylase 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3