Fluoxetine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A aromatic ether consisting of 4-trifluoromethylphenol substituted on oxygen by a 3-(methylamino)-1-phenylpropyl group. (Chemical Entities of Biological Interest Ontology, CHEBI_5118)
External Link http://ctdbase.org/detail.go?type=chem&acc=D005473
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Genes

114 genes/proteins interacting with the chemical Fluoxetine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
ANXA5 annexin A5
ARRB2 arrestin, beta 2
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARTPT CART prepropeptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE1 cyclin E1
CD8A CD8a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CES1 carboxylesterase 1
CKS1B CDC28 protein kinase regulatory subunit 1B
CNR1 cannabinoid receptor 1 (brain)
CREB1 cAMP responsive element binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DIO3 deiodinase, iodothyronine, type III
DRD3 dopamine receptor D3
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GLO1 glyoxalase I
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GSK3B glycogen synthase kinase 3 beta
HBG2 hemoglobin, gamma G
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HRH1 histamine receptor H1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IFNA1 interferon, alpha 1
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JAG1 jagged 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNK2 potassium channel, two pore domain subfamily K, member 2
L1CAM L1 cell adhesion molecule
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MBD1 methyl-CpG binding domain protein 1
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGFR nerve growth factor receptor
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRM1 opioid receptor, mu 1
OXTR oxytocin receptor
PDE4B phosphodiesterase 4B, cAMP-specific
PDYN prodynorphin
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POMC proopiomelanocortin
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKG1 protein kinase, cGMP-dependent, type I
PRL prolactin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100B S100 calcium binding protein B
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD1 SMAD family member 1
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TPH2 tryptophan hydroxylase 2
VLDLR very low density lipoprotein receptor
WNT3A wingless-type MMTV integration site family, member 3A
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta