| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | An anabolic androgenic steroid that has formula C20H29FO3. (Chemical Entities of Biological Interest Ontology, CHEBI_5120) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/6446 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Fluoxymesterone relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPHA4 | EPH receptor A4 | 1.39 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 1.37 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 1.29 |
| FBXW2 | F-box and WD repeat domain containing 2 | 1.24 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 1.21 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 1.01 |
| CDCA4 | cell division cycle associated 4 | 0.95 |
| TUB | tubby bipartite transcription factor | 0.9 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.85 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 | 0.75 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.74 |
| SLC6A17 | solute carrier family 6 (neutral amino acid transporter), member 17 | 0.72 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | 0.72 |
| RUNDC1 | RUN domain containing 1 | 0.68 |
| HMBOX1 | homeobox containing 1 | 0.68 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 0.64 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.63 |
| DOP1A | DOP1 leucine zipper like protein A | 0.63 |
| TMEM186 | transmembrane protein 186 | 0.61 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.57 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.56 |
| SMCR8 | Smith-Magenis syndrome chromosome region, candidate 8 | 0.56 |
| ZNF428 | zinc finger protein 428 | 0.53 |
| CASTOR2 | cytosolic arginine sensor for mTORC1 subunit 2 | 0.53 |
| C7 | complement component 7 | 0.51 |
| PHF1 | PHD finger protein 1 | 0.51 |
| KCTD2 | potassium channel tetramerization domain containing 2 | 0.48 |
| ZNF397 | zinc finger protein 397 | 0.47 |
| FZD3 | frizzled class receptor 3 | 0.47 |
| NADK | NAD kinase | 0.46 |
| LRP11 | low density lipoprotein receptor-related protein 11 | 0.45 |
| PRAME | preferentially expressed antigen in melanoma | 0.45 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 | 0.44 |
| PISD | phosphatidylserine decarboxylase | 0.44 |
| LRFN1 | leucine rich repeat and fibronectin type III domain containing 1 | 0.44 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.43 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.42 |
| EED | embryonic ectoderm development | 0.4 |
| ZNF286B | zinc finger protein 286B | 0.4 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.39 |
| LRRC45 | leucine rich repeat containing 45 | 0.39 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.38 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.38 |
| NRP1 | neuropilin 1 | 0.37 |
| CPN1 | carboxypeptidase N, polypeptide 1 | 0.37 |
| MYPOP | Myb-related transcription factor, partner of profilin | 0.37 |
| DOLK | dolichol kinase | 0.36 |
| FTL | ferritin, light polypeptide | 0.36 |
| ZNF593 | zinc finger protein 593 | 0.36 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | 0.36 |
| SELENOW | selenoprotein W | 0.36 |
| ANKRD18B | ankyrin repeat domain 18B | 0.35 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.35 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.35 |
| GLMP | glycosylated lysosomal membrane protein | 0.34 |
| CLTCL1 | clathrin, heavy chain-like 1 | 0.34 |
| SYBU | syntabulin (syntaxin-interacting) | 0.34 |
| C1ORF50 | chromosome 1 open reading frame 50 | 0.33 |
| KSR1 | kinase suppressor of ras 1 | 0.33 |
| RAD51D | RAD51 paralog D | 0.32 |
| POTEE | POTE ankyrin domain family, member E | 0.31 |
| B2M | beta-2-microglobulin | 0.3 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.3 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.3 |
| C5 | complement component 5 | 0.3 |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.3 |
| TEAD2 | TEA domain family member 2 | 0.3 |
| DNA2 | DNA replication helicase/nuclease 2 | 0.3 |
| ACOT8 | acyl-CoA thioesterase 8 | 0.3 |
| MRFAP1 | Morf4 family associated protein 1 | 0.29 |
| H3-3A | H3.3 histone A | 0.29 |
| TMEM230 | transmembrane protein 230 | 0.29 |
| KMT5C | lysine methyltransferase 5C | 0.29 |
| HTT | huntingtin | 0.29 |
| ZNF888 | zinc finger protein 888 | 0.29 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 0.29 |
| CFAP58 | cilia and flagella associated protein 58 | 0.29 |
| COL6A3 | collagen, type VI, alpha 3 | 0.28 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.28 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) | 0.28 |
| GPN3 | GPN-loop GTPase 3 | 0.28 |
| SBSN | suprabasin | 0.28 |
| TYSND1 | trypsin domain containing 1 | 0.27 |
| PRELID3B | PRELI domain containing 3B | 0.27 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.27 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.27 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | 0.27 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.26 |
| TAF3 | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa | 0.26 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) | 0.26 |
| COMMD6 | COMM domain containing 6 | 0.26 |
| NOMO1 | NODAL modulator 1 | 0.26 |
| ZNF14 | zinc finger protein 14 | 0.26 |
| ZNF823 | zinc finger protein 823 | 0.25 |
| TRNP1 | TMF1-regulated nuclear protein 1 | 0.25 |
| HSBP1 | heat shock factor binding protein 1 | 0.25 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.25 |
| RP9 | retinitis pigmentosa 9 (autosomal dominant) | 0.25 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.25 |
| DGKH | diacylglycerol kinase, eta | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | -2.3 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | -1.71 |
| NUDT12 | nudix (nucleoside diphosphate linked moiety X)-type motif 12 | -0.9 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.6 |
| MAGEA12 | melanoma antigen family A12 | -0.59 |
| TREX1 | three prime repair exonuclease 1 | -0.56 |
| AGTRAP | angiotensin II receptor-associated protein | -0.54 |
| ZNF524 | zinc finger protein 524 | -0.54 |
| ZNF624 | zinc finger protein 624 | -0.53 |
| TMEM9 | transmembrane protein 9 | -0.52 |
| ENDOV | endonuclease V | -0.5 |
| GJC1 | gap junction protein, gamma 1, 45kDa | -0.49 |
| PYGM | phosphorylase, glycogen, muscle | -0.48 |
| RPUSD1 | RNA pseudouridylate synthase domain containing 1 | -0.47 |
| SLC25A52 | solute carrier family 25, member 52 | -0.43 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.43 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -0.41 |
| PXYLP1 | 2-phosphoxylose phosphatase 1 | -0.41 |
| ZNF12 | zinc finger protein 12 | -0.4 |
| LRRC28 | leucine rich repeat containing 28 | -0.38 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.37 |
| MEF2A | myocyte enhancer factor 2A | -0.37 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.36 |
| ZNF91 | zinc finger protein 91 | -0.35 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.34 |
| ZBED6 | zinc finger, BED-type containing 6 | -0.34 |
| RINL | Ras and Rab interactor-like | -0.34 |
| SMIM12 | small integral membrane protein 12 | -0.33 |
| RETREG2 | reticulophagy regulator family member 2 | -0.33 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.33 |
| GPR161 | G protein-coupled receptor 161 | -0.33 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.33 |
| ATG4D | autophagy related 4D, cysteine peptidase | -0.32 |
| ANKRD13B | ankyrin repeat domain 13B | -0.32 |
| LZTR1 | leucine-zipper-like transcription regulator 1 | -0.32 |
| MLXIPL | MLX interacting protein-like | -0.32 |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 | -0.32 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.31 |
| HGFAC | HGF activator | -0.3 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.3 |
| PMF1 | polyamine-modulated factor 1 | -0.29 |
| ANXA6 | annexin A6 | -0.29 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.29 |
| PRXL2A | peroxiredoxin like 2A | -0.29 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | -0.29 |
| KALRN | kalirin, RhoGEF kinase | -0.29 |
| TMEM135 | transmembrane protein 135 | -0.29 |
| KRTCAP3 | keratinocyte associated protein 3 | -0.29 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | -0.29 |
| IQCB1 | IQ motif containing B1 | -0.28 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | -0.28 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 | -0.28 |
| COMMD10 | COMM domain containing 10 | -0.28 |
| ATG4A | autophagy related 4A, cysteine peptidase | -0.28 |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) | -0.27 |
| GTDC1 | glycosyltransferase-like domain containing 1 | -0.27 |
| C2ORF42 | chromosome 2 open reading frame 42 | -0.27 |
| ZNF324 | zinc finger protein 324 | -0.27 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.27 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.27 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.27 |
| CDC26 | cell division cycle 26 | -0.27 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.26 |
| MOB3A | MOB kinase activator 3A | -0.26 |
| TOMM40L | translocase of outer mitochondrial membrane 40 homolog (yeast)-like | -0.26 |
| ETV3 | ets variant 3 | -0.26 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | -0.26 |
| RCAN1 | regulator of calcineurin 1 | -0.26 |
| ZNF511 | zinc finger protein 511 | -0.26 |
| PLEC | plectin | -0.26 |
| WASHC3 | WASH complex subunit 3 | -0.25 |
| TSTD1 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 | -0.25 |
| ALPK1 | alpha-kinase 1 | -0.25 |
| YAF2 | YY1 associated factor 2 | -0.25 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.25 |
| RNF130 | ring finger protein 130 | -0.25 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | -0.25 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.25 |
| TJAP1 | tight junction associated protein 1 (peripheral) | -0.25 |
| MAGEA6 | melanoma antigen family A6 | -0.25 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | -0.25 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.24 |
| ZNF227 | zinc finger protein 227 | -0.24 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.24 |
| GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | -0.24 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | -0.24 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 | -0.24 |
| IL27RA | interleukin 27 receptor, alpha | -0.24 |
| NRBP2 | nuclear receptor binding protein 2 | -0.24 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.24 |
| PSAP | prosaposin | -0.24 |
| ZNF460 | zinc finger protein 460 | -0.24 |
| MAPK12 | mitogen-activated protein kinase 12 | -0.23 |
| GPAT2 | glycerol-3-phosphate acyltransferase 2, mitochondrial | -0.23 |
| DZIP3 | DAZ interacting zinc finger protein 3 | -0.23 |
| C17ORF53 | chromosome 17 open reading frame 53 | -0.23 |
| GATA6 | GATA binding protein 6 | -0.23 |
| CST6 | cystatin E/M | -0.23 |
| ETAA1 | Ewing tumor-associated antigen 1 | -0.23 |
