| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.260564 |
| LOX | lysyl oxidase | 0.17174 |
| NDRG1 | N-myc downstream regulated 1 | 0.115652 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.114768 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.112031 |
| PODXL | podocalyxin-like | 0.0815905 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0815294 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0813816 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0725288 |
| LOXL2 | lysyl oxidase-like 2 | 0.0673375 |
| C1D | C1D nuclear receptor corepressor | 0.0664701 |
| FLNA | filamin A, alpha | 0.0622642 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0555799 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0521312 |
| CD44 | CD44 molecule (Indian blood group) | 0.0514117 |
| L1CAM | L1 cell adhesion molecule | 0.0511025 |
| THBS2 | thrombospondin 2 | 0.0488144 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0438619 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0431103 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0430405 |
| EGFR | epidermal growth factor receptor | 0.0421135 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420723 |
| STC1 | stanniocalcin 1 | 0.0407274 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0406838 |
| ATP13A3 | ATPase type 13A3 | 0.0391524 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0383871 |
| HDAC9 | histone deacetylase 9 | 0.0367298 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0357258 |
| CD109 | CD109 molecule | 0.0352482 |
| PRELID2 | PRELI domain containing 2 | 0.0334469 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0332326 |
| GPC6 | glypican 6 | 0.033008 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0329791 |
| FLNB | filamin B, beta | 0.0325785 |
| SFTPA2 | surfactant protein A2 | 0.0320254 |
| LDHA | lactate dehydrogenase A | 0.0318698 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0316335 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0305383 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0299007 |
| FNIP1 | folliculin interacting protein 1 | 0.0290806 |
| SLC22A23 | solute carrier family 22, member 23 | 0.028825 |
| YEATS2 | YEATS domain containing 2 | 0.0283997 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.027858 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0274015 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0272642 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0270639 |
| ARRDC3 | arrestin domain containing 3 | 0.0263782 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0262097 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0252458 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0250566 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246526 |
| MYO9A | myosin IXA | 0.0245256 |
| NAV2 | neuron navigator 2 | 0.0242443 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0240614 |
| RPS3 | ribosomal protein S3 | 0.0240378 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0239288 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0238913 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0237325 |
| MYADM | myeloid-associated differentiation marker | 0.0234087 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0231817 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0229867 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0222861 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0220135 |
| STK10 | serine/threonine kinase 10 | 0.0217763 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.02161 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213029 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0210757 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0209964 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0209867 |
| APP | amyloid beta (A4) precursor protein | 0.0209752 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0209572 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0208859 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0208197 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0207559 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0204833 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0204798 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0204667 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0201756 |
| RPS2 | ribosomal protein S2 | 0.0201621 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0198374 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0198324 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0194318 |
| ANK2 | ankyrin 2, neuronal | 0.0188441 |
| RACK1 | receptor for activated C kinase 1 | 0.0188402 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0188035 |
| ITSN2 | intersectin 2 | 0.0187432 |
| UBAP1 | ubiquitin associated protein 1 | 0.018522 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0184713 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0184326 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0183693 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0183596 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0183438 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0182228 |
| TMOD1 | tropomodulin 1 | 0.0182025 |
| NOTCH2 | notch 2 | 0.0181634 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0179839 |
| DEPP1 | DEPP autophagy regulator 1 | 0.017933 |
| CEP350 | centrosomal protein 350kDa | 0.0179204 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0179177 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0178426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.250314 |
| AHNAK | AHNAK nucleoprotein | -0.191397 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171899 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.139997 |
| S100A10 | S100 calcium binding protein A10 | -0.11284 |
| CDH13 | cadherin 13 | -0.0771525 |
| CANX | calnexin | -0.0770759 |
| TMSB10 | thymosin beta 10 | -0.0759553 |
| FN1 | fibronectin 1 | -0.0741907 |
| VIM | vimentin | -0.0731817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0696241 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.068127 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0652501 |
| PTMA | prothymosin, alpha | -0.0643549 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0586751 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0564641 |
| MAP1B | microtubule-associated protein 1B | -0.0551122 |
| MEIS2 | Meis homeobox 2 | -0.0531842 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0530364 |
| MX2 | MX dynamin-like GTPase 2 | -0.0517368 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0501204 |
| SUCNR1 | succinate receptor 1 | -0.0484022 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0451541 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0446534 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0435163 |
| FSTL1 | follistatin-like 1 | -0.0431531 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0429751 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.042246 |
| POTEF | POTE ankyrin domain family, member F | -0.0419454 |
| CD99 | CD99 molecule | -0.0413877 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0408097 |
| NAV1 | neuron navigator 1 | -0.040368 |
| RRBP1 | ribosome binding protein 1 | -0.039975 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0395932 |
| DCLK2 | doublecortin-like kinase 2 | -0.0388369 |
| CENPF | centromere protein F, 350/400kDa | -0.037861 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0375893 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.037552 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0374792 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0373107 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.036246 |
| UBC | ubiquitin C | -0.0354071 |
| TPM1 | tropomyosin 1 (alpha) | -0.0350569 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0349802 |
| CUX1 | cut-like homeobox 1 | -0.0348826 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0348656 |
| LMNA | lamin A/C | -0.0348576 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0347826 |
| RPS6 | ribosomal protein S6 | -0.033993 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.03385 |
| TPM4 | tropomyosin 4 | -0.0337432 |
| PRSS23 | protease, serine, 23 | -0.0332049 |
| TMSB4X | thymosin beta 4, X-linked | -0.0327324 |
| RPS24 | ribosomal protein S24 | -0.0321191 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0320778 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0308741 |
| CSTB | cystatin B (stefin B) | -0.0303375 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0298719 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0295848 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0294107 |
| PARD3 | par-3 family cell polarity regulator | -0.0285367 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0284552 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0282433 |
| CAVIN1 | caveolae associated protein 1 | -0.0277757 |
| COL5A2 | collagen, type V, alpha 2 | -0.0272035 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0270976 |
| RIGI | RNA sensor RIG-I | -0.0268187 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0264219 |
| ASPH | aspartate beta-hydroxylase | -0.0263033 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0261223 |
| SRPK2 | SRSF protein kinase 2 | -0.0260469 |
| LRRC17 | leucine rich repeat containing 17 | -0.0260463 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0258997 |
| TUBB | tubulin, beta class I | -0.0258862 |
| H3-3B | H3.3 histone B | -0.0258029 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0256409 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0256014 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0253782 |
| CDK6 | cyclin-dependent kinase 6 | -0.0252208 |
| RPL28 | ribosomal protein L28 | -0.0251489 |
| HMGB1 | high mobility group box 1 | -0.0250234 |
| RPS15 | ribosomal protein S15 | -0.0249426 |
| IL7R | interleukin 7 receptor | -0.024841 |
| PLXNA2 | plexin A2 | -0.0243746 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0242947 |
| RPLP2 | ribosomal protein, large, P2 | -0.0242159 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0241561 |
| PTK2 | protein tyrosine kinase 2 | -0.024018 |
| DEK | DEK proto-oncogene | -0.0239313 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.023833 |
| IER3 | immediate early response 3 | -0.0235593 |
| SP100 | SP100 nuclear antigen | -0.0232306 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0228418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0227772 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0226192 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0224654 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0224372 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0224255 |
| PCDH7 | protocadherin 7 | -0.0224006 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0223341 |
