| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flutamide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.215217 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.194974 |
| MT2A | metallothionein 2A | 0.144108 |
| CD44 | CD44 molecule (Indian blood group) | 0.137118 |
| VIM | vimentin | 0.129448 |
| LOX | lysyl oxidase | 0.104897 |
| STC1 | stanniocalcin 1 | 0.104782 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0752359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0715212 |
| NDRG1 | N-myc downstream regulated 1 | 0.0686845 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0629709 |
| LDHA | lactate dehydrogenase A | 0.0611621 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0528141 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0527267 |
| HAS2 | hyaluronan synthase 2 | 0.0525572 |
| LOXL2 | lysyl oxidase-like 2 | 0.0498354 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0442085 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0437726 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0374038 |
| ARRDC3 | arrestin domain containing 3 | 0.0365365 |
| MT1X | metallothionein 1X | 0.0363669 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0360348 |
| KLF6 | Kruppel-like factor 6 | 0.0355129 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0351086 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0351043 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.034749 |
| ECE1 | endothelin converting enzyme 1 | 0.033588 |
| VCAN | versican | 0.0313241 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0303719 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0286796 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0286598 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0283999 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0283984 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0282033 |
| CALR | calreticulin | 0.0266312 |
| POSTN | periostin, osteoblast specific factor | 0.0263504 |
| MKI67 | marker of proliferation Ki-67 | 0.0258618 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0242311 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0238629 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0237665 |
| INHBA | inhibin, beta A | 0.0236838 |
| MAP1B | microtubule-associated protein 1B | 0.0229738 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0228378 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.022432 |
| ATP13A3 | ATPase type 13A3 | 0.0223821 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0223199 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.021888 |
| CENPF | centromere protein F, 350/400kDa | 0.0218657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.021381 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0212634 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0209822 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0208611 |
| DUSP6 | dual specificity phosphatase 6 | 0.0204748 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0202753 |
| SDC2 | syndecan 2 | 0.0192605 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0184311 |
| CDC27 | cell division cycle 27 | 0.0183393 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0175869 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0174853 |
| ANGPTL4 | angiopoietin-like 4 | 0.0173967 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0173499 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0172612 |
| PRELID2 | PRELI domain containing 2 | 0.0171036 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0168875 |
| ANKRD12 | ankyrin repeat domain 12 | 0.016789 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0165541 |
| CTSB | cathepsin B | 0.0163304 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0162308 |
| HLA-B | major histocompatibility complex, class I, B | 0.0161695 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0161525 |
| PFN1 | profilin 1 | 0.0159561 |
| CD59 | CD59 molecule, complement regulatory protein | 0.015384 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0151461 |
| OSMR | oncostatin M receptor | 0.0149077 |
| YEATS2 | YEATS domain containing 2 | 0.0147967 |
| S100A6 | S100 calcium binding protein A6 | 0.0145722 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0142491 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0142411 |
| MTSS1 | metastasis suppressor 1 | 0.0139214 |
| VEGFC | vascular endothelial growth factor C | 0.0138982 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0136447 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0136241 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0135262 |
| FLNC | filamin C, gamma | 0.0133555 |
| SQLE | squalene epoxidase | 0.0133374 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0131695 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0130471 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0130077 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0129125 |
| IKZF2 | IKAROS family zinc finger 2 (Helios) | 0.0127336 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0127225 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0126964 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0125778 |
| CA12 | carbonic anhydrase XII | 0.0125581 |
| SFTPA2 | surfactant protein A2 | 0.0123929 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0123556 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0122301 |
| PYGL | phosphorylase, glycogen, liver | 0.0121611 |
| CBX3 | chromobox homolog 3 | 0.012083 |
| CENPE | centromere protein E, 312kDa | 0.0120042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.188854 |
| CDH13 | cadherin 13 | -0.128905 |
| COL1A1 | collagen, type I, alpha 1 | -0.107969 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0984994 |
| CADM1 | cell adhesion molecule 1 | -0.0938692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.081435 |
| AHNAK | AHNAK nucleoprotein | -0.0698047 |
| RPS6 | ribosomal protein S6 | -0.0573197 |
| COL5A1 | collagen, type V, alpha 1 | -0.053516 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0524738 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0475689 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0458054 |
| COL1A2 | collagen, type I, alpha 2 | -0.0449998 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.043938 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0437042 |
| CALD1 | caldesmon 1 | -0.0428515 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.042577 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0408212 |
| GOLGB1 | golgin B1 | -0.0408016 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0400982 |
| SQSTM1 | sequestosome 1 | -0.039833 |
| RPL35A | ribosomal protein L35a | -0.0393442 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0393041 |
| IER3 | immediate early response 3 | -0.0386434 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0383875 |
| PTMA | prothymosin, alpha | -0.0377743 |
| FBN1 | fibrillin 1 | -0.0375889 |
| CANX | calnexin | -0.0375678 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0371764 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0352276 |
| PTK2 | protein tyrosine kinase 2 | -0.0339736 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0333185 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0331374 |
| QKI | QKI, KH domain containing, RNA binding | -0.0321405 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.032096 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0313281 |
| MAP4 | microtubule-associated protein 4 | -0.0300916 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0296203 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0294216 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0287997 |
| ACTG1 | actin gamma 1 | -0.0285017 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0282952 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0282093 |
| TPM1 | tropomyosin 1 (alpha) | -0.0281227 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.027996 |
| IL6ST | interleukin 6 signal transducer | -0.0277714 |
| TPM4 | tropomyosin 4 | -0.0274197 |
| RPL5 | ribosomal protein L5 | -0.0272713 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0266812 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0266636 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0265898 |
| RPS8 | ribosomal protein S8 | -0.0262741 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0255545 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0252745 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0252564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0252477 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0245765 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0244704 |
| MTDH | metadherin | -0.0243833 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0243472 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239908 |
| FOXP1 | forkhead box P1 | -0.0238885 |
| RBM39 | RNA binding motif protein 39 | -0.023731 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0237242 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0234223 |
| ASPH | aspartate beta-hydroxylase | -0.0232514 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0228936 |
| IRF1 | interferon regulatory factor 1 | -0.0226533 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0225047 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0223478 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0222632 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.022142 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0219628 |
| DGKI | diacylglycerol kinase, iota | -0.0217736 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0215835 |
| CUX1 | cut-like homeobox 1 | -0.0214828 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0213573 |
| DSTN | destrin (actin depolymerizing factor) | -0.0213512 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0211151 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0208165 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0207893 |
| CNTN5 | contactin 5 | -0.0207188 |
| RPLP1 | ribosomal protein, large, P1 | -0.0205867 |
| RHEB | Ras homolog enriched in brain | -0.0205263 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0204558 |
| NEK10 | NIMA-related kinase 10 | -0.0204196 |
| PALLD | palladin, cytoskeletal associated protein | -0.0203855 |
| TMSB10 | thymosin beta 10 | -0.0203475 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0201495 |
| EXOC4 | exocyst complex component 4 | -0.0201144 |
| POTEF | POTE ankyrin domain family, member F | -0.0200579 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0199625 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0196177 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0195021 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0194286 |
| TFG | TRK-fused gene | -0.0193547 |
| NABP1 | nucleic acid binding protein 1 | -0.0190975 |
| HYOU1 | hypoxia up-regulated 1 | -0.0189947 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0189737 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0189535 |
