| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0993898 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0782471 |
| EREG | epiregulin | 0.0547634 |
| NDRG1 | N-myc downstream regulated 1 | 0.0521943 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0485053 |
| RNF43 | ring finger protein 43 | 0.0481836 |
| RPS12 | ribosomal protein S12 | 0.0431551 |
| ONECUT3 | one cut homeobox 3 | 0.0396418 |
| RPS2 | ribosomal protein S2 | 0.0368035 |
| AREG | amphiregulin | 0.0352181 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0332833 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0312569 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0311364 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0295833 |
| MYO1E | myosin IE | 0.0287083 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0282509 |
| PRELID2 | PRELI domain containing 2 | 0.0279407 |
| FAT1 | FAT atypical cadherin 1 | 0.0272625 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0269341 |
| CALR | calreticulin | 0.0266266 |
| ACTG1 | actin gamma 1 | 0.0265192 |
| PCBP1 | poly(rC) binding protein 1 | 0.0264877 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0263343 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257983 |
| CDCP1 | CUB domain containing protein 1 | 0.0255416 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0253036 |
| PGK1 | phosphoglycerate kinase 1 | 0.0243619 |
| KLF6 | Kruppel-like factor 6 | 0.0233735 |
| PRSS3 | protease, serine, 3 | 0.0231034 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230441 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0223736 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0217398 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0215998 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0214929 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0211023 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0210913 |
| LAMC2 | laminin, gamma 2 | 0.0210693 |
| TNS4 | tensin 4 | 0.0206425 |
| LDHA | lactate dehydrogenase A | 0.0206418 |
| RPL23 | ribosomal protein L23 | 0.0202028 |
| FAM13A | family with sequence similarity 13, member A | 0.0191057 |
| GAK | cyclin G associated kinase | 0.0189668 |
| FHL2 | four and a half LIM domains 2 | 0.0188856 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0186903 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0186632 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0182942 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0182907 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0181737 |
| CLIC1 | chloride intracellular channel 1 | 0.0176878 |
| SFTPA2 | surfactant protein A2 | 0.017584 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0173056 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0168947 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0168074 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0162956 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.016232 |
| RPLP0 | ribosomal protein, large, P0 | 0.0161433 |
| ATXN1 | ataxin 1 | 0.015872 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0157358 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0155813 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0155088 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.015437 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0151991 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0151281 |
| TWF1 | twinfilin actin binding protein 1 | 0.0148944 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0148177 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0142676 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0142244 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0141257 |
| DUSP4 | dual specificity phosphatase 4 | 0.0140394 |
| IGFL2 | IGF-like family member 2 | 0.0139687 |
| NEBL | nebulette | 0.0139146 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0138583 |
| TRIB3 | tribbles pseudokinase 3 | 0.0138476 |
| CLTC | clathrin, heavy chain (Hc) | 0.0138225 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.013801 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0137916 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0137175 |
| B2M | beta-2-microglobulin | 0.0136911 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0136603 |
| RPL4 | ribosomal protein L4 | 0.0135998 |
| SERINC1 | serine incorporator 1 | 0.0134948 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0134326 |
| SET | SET nuclear proto-oncogene | 0.0131602 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0130253 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0129165 |
| KIF5B | kinesin family member 5B | 0.0128819 |
| TRIOBP | TRIO and F-actin binding protein | 0.0128532 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0126358 |
| ANXA2 | annexin A2 | 0.012612 |
| CD44 | CD44 molecule (Indian blood group) | 0.0126027 |
| PKP2 | plakophilin 2 | 0.0125569 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.0124597 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0124512 |
| PTCH1 | patched 1 | 0.0123707 |
| PDZD8 | PDZ domain containing 8 | 0.012333 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0122917 |
| JAG1 | jagged 1 | 0.0122803 |
| ARF1 | ADP-ribosylation factor 1 | 0.0122549 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0119616 |
| FLNA | filamin A, alpha | 0.0118024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.164747 |
| PTMA | prothymosin, alpha | -0.152348 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.139508 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.112487 |
| ITGA6 | integrin, alpha 6 | -0.108973 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.101106 |
| TMSB10 | thymosin beta 10 | -0.0974387 |
| EZR | ezrin | -0.0950342 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0892802 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0836314 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0709564 |
| GPHN | gephyrin | -0.0708673 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706976 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.065692 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0644606 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.060994 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0599199 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0595581 |
| RPS6 | ribosomal protein S6 | -0.0583606 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0548892 |
| EMP1 | epithelial membrane protein 1 | -0.0519869 |
| CALB1 | calbindin 1, 28kDa | -0.0502632 |
| LMO7 | LIM domain 7 | -0.0474201 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0444425 |
| ANXA1 | annexin A1 | -0.0440695 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0438731 |
| AHNAK | AHNAK nucleoprotein | -0.0437418 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0433518 |
| EHBP1 | EH domain binding protein 1 | -0.0426647 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0415563 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0413894 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401464 |
| DSTN | destrin (actin depolymerizing factor) | -0.0398198 |
| GOLGA4 | golgin A4 | -0.0395903 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0393953 |
| RNF217 | ring finger protein 217 | -0.0392496 |
| KRT18 | keratin 18, type I | -0.0390598 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0372221 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0370157 |
| AGR2 | anterior gradient 2 | -0.0369641 |
| LMNA | lamin A/C | -0.0363018 |
| MSI2 | musashi RNA-binding protein 2 | -0.036133 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0361269 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.03594 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.03581 |
| CD2AP | CD2-associated protein | -0.0343857 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0339675 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.033887 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0336901 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0333096 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0327533 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0326638 |
| S100A6 | S100 calcium binding protein A6 | -0.0326449 |
| PARD3 | par-3 family cell polarity regulator | -0.0325382 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.032481 |
| NFIA | nuclear factor I/A | -0.0324185 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0318932 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0316732 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0316564 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0316169 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0310634 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0307852 |
| CANX | calnexin | -0.0306391 |
| SBF2 | SET binding factor 2 | -0.0301439 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0297835 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0294944 |
| SETD5 | SET domain containing 5 | -0.0292308 |
| PTK2 | protein tyrosine kinase 2 | -0.0291957 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0290786 |
| ASPH | aspartate beta-hydroxylase | -0.028921 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.028803 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0286826 |
| PKP4 | plakophilin 4 | -0.0285477 |
| MUC17 | mucin 17, cell surface associated | -0.0282812 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0280176 |
| FLNB | filamin B, beta | -0.0280108 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.027868 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0273979 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0273963 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0272443 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.027093 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0267506 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0267452 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0266491 |
| ADD3 | adducin 3 (gamma) | -0.0265383 |
| NOP58 | NOP58 ribonucleoprotein | -0.0264906 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0264273 |
| UBE3C | ubiquitin protein ligase E3C | -0.0262128 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0261672 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0261304 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0260895 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0259296 |
| MAP4 | microtubule-associated protein 4 | -0.0258631 |
| THOC2 | THO complex 2 | -0.0258044 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0257675 |
| USP34 | ubiquitin specific peptidase 34 | -0.025585 |
| MECOM | MDS1 and EVI1 complex locus | -0.0254129 |
| EVI5 | ecotropic viral integration site 5 | -0.0251959 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0251417 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0251028 |
