| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.202102 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.144659 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0930637 |
| NDRG1 | N-myc downstream regulated 1 | 0.0826863 |
| LAMC2 | laminin, gamma 2 | 0.0767979 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0635014 |
| SPAG9 | sperm associated antigen 9 | 0.0553857 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0545784 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.048184 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0440219 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0424914 |
| ARRDC3 | arrestin domain containing 3 | 0.042073 |
| CES1 | carboxylesterase 1 | 0.0416157 |
| MCL1 | myeloid cell leukemia 1 | 0.036655 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0361287 |
| MKI67 | marker of proliferation Ki-67 | 0.0348615 |
| MT2A | metallothionein 2A | 0.0346997 |
| NGLY1 | N-glycanase 1 | 0.0344391 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0337019 |
| FAM13A | family with sequence similarity 13, member A | 0.0325782 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0308679 |
| FRY | furry homolog (Drosophila) | 0.0301625 |
| STC1 | stanniocalcin 1 | 0.0301618 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0297657 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0297283 |
| NPC1 | Niemann-Pick disease, type C1 | 0.029327 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.028605 |
| SLTM | SAFB-like, transcription modulator | 0.0280636 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0268087 |
| LAMB3 | laminin, beta 3 | 0.0267606 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0264573 |
| UBC | ubiquitin C | 0.0257777 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0254929 |
| TMEM165 | transmembrane protein 165 | 0.0245702 |
| LAMA4 | laminin, alpha 4 | 0.0239461 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0235552 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230196 |
| EGR1 | early growth response 1 | 0.0229891 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0222902 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0220744 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0220006 |
| KIAA1217 | KIAA1217 | 0.021323 |
| WDR45B | WD repeat domain 45B | 0.0211929 |
| ATP13A3 | ATPase type 13A3 | 0.0209349 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0208711 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0207893 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0205873 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0198273 |
| RUNX1 | runt-related transcription factor 1 | 0.019811 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0195443 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.019397 |
| GPATCH2L | G patch domain containing 2-like | 0.0191609 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0190464 |
| JMJD1C | jumonji domain containing 1C | 0.0188237 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0183924 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0182465 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0181196 |
| EP300 | E1A binding protein p300 | 0.0181059 |
| FNIP1 | folliculin interacting protein 1 | 0.0180631 |
| DTNA | dystrobrevin, alpha | 0.0177748 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0176876 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0175579 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0174065 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0172125 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0172118 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0170494 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0170161 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.016903 |
| YEATS2 | YEATS domain containing 2 | 0.0168398 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.016604 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0164278 |
| CSNK1E | casein kinase 1, epsilon | 0.0164251 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0162722 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0162202 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0160069 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0158882 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0157476 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0156335 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0155456 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.015514 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0153624 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0153621 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0148637 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0148015 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0146022 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0140858 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0140774 |
| CCNH | cyclin H | 0.0140121 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0137705 |
| HLA-B | major histocompatibility complex, class I, B | 0.0137696 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0137001 |
| F11R | F11 receptor | 0.0133488 |
| SYAP1 | synapse associated protein 1 | 0.0132978 |
| SEPTIN2 | septin 2 | 0.0132677 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.013244 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0131199 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0130305 |
| MYO1B | myosin IB | 0.0130062 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0129718 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.012902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.167426 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.148024 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.11918 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0773045 |
| EGFR | epidermal growth factor receptor | -0.0717705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0677985 |
| MYOF | myoferlin | -0.0663655 |
| GRAMD1B | GRAM domain containing 1B | -0.0622327 |
| TXNRD1 | thioredoxin reductase 1 | -0.0568409 |
| SCEL | sciellin | -0.0539295 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0521391 |
| TMSB10 | thymosin beta 10 | -0.0510741 |
| AHNAK | AHNAK nucleoprotein | -0.0471924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0471538 |
| LMO7 | LIM domain 7 | -0.0468085 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0460679 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0456597 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0455975 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0436312 |
| KRT7 | keratin 7, type II | -0.0421816 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0413769 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0411324 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0402061 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0401509 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0384206 |
| INTS6 | integrator complex subunit 6 | -0.0361348 |
| CUX1 | cut-like homeobox 1 | -0.0355889 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0337172 |
| H1-0 | H1.0 linker histone | -0.0332195 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0320939 |
| ACTG1 | actin gamma 1 | -0.0319396 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0307749 |
| CCND1 | cyclin D1 | -0.0305668 |
| PKM | pyruvate kinase, muscle | -0.0303024 |
| FLNB | filamin B, beta | -0.0295147 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0291287 |
| CMIP | c-Maf inducing protein | -0.029119 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0286934 |
| SMYD3 | SET and MYND domain containing 3 | -0.0285072 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0282428 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0282152 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0275982 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0275313 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0273539 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0271447 |
| TNS3 | tensin 3 | -0.0270219 |
| FOXP1 | forkhead box P1 | -0.0264145 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0261073 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0255011 |
| PTMA | prothymosin, alpha | -0.0253951 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0253897 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0252725 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0249862 |
| PATJ | PATJ crumbs cell polarity complex component | -0.024814 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0245949 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0243442 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.024189 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0241082 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0240145 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0238043 |
| PRKCA | protein kinase C, alpha | -0.0237935 |
| KRT8 | keratin 8, type II | -0.0237208 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0234441 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0232684 |
| PARD3 | par-3 family cell polarity regulator | -0.0231353 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0228926 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0226567 |
| CTBP2 | C-terminal binding protein 2 | -0.0224114 |
| EHBP1 | EH domain binding protein 1 | -0.0219391 |
| KRT18 | keratin 18, type I | -0.0217106 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0214565 |
| PTK2 | protein tyrosine kinase 2 | -0.0214299 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0214121 |
| SMAD3 | SMAD family member 3 | -0.0213553 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0207797 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0199404 |
| RAB10 | RAB10, member RAS oncogene family | -0.0198748 |
| EFNA5 | ephrin-A5 | -0.0196601 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.019632 |
| SDC1 | syndecan 1 | -0.0196168 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0195339 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0193178 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0193133 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0189556 |
| RASAL2 | RAS protein activator like 2 | -0.01895 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0188722 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0187397 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0185111 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0183553 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0182499 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0181771 |
| MCU | mitochondrial calcium uniporter | -0.0179504 |
| DST | dystonin | -0.0177383 |
| POTEF | POTE ankyrin domain family, member F | -0.0172439 |
| TPM4 | tropomyosin 4 | -0.0171255 |
| CANX | calnexin | -0.0171029 |
| APP | amyloid beta (A4) precursor protein | -0.016846 |
| ITGA6 | integrin, alpha 6 | -0.01666 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0166445 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0166411 |
