| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.177102 |
| VIM | vimentin | 0.112188 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0955917 |
| FN1 | fibronectin 1 | 0.0885529 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0875911 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.08616 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.082418 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0814772 |
| STC1 | stanniocalcin 1 | 0.0795307 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0787422 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0785657 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0742127 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0716349 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0711654 |
| NDRG1 | N-myc downstream regulated 1 | 0.0665338 |
| MEF2A | myocyte enhancer factor 2A | 0.0565959 |
| CD44 | CD44 molecule (Indian blood group) | 0.0554737 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0533155 |
| EGFR | epidermal growth factor receptor | 0.0531372 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0526753 |
| PCBP2 | poly(rC) binding protein 2 | 0.0517498 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0508873 |
| TGM2 | transglutaminase 2 | 0.0483027 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0465733 |
| USP34 | ubiquitin specific peptidase 34 | 0.0460068 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0455261 |
| MTSS1 | metastasis suppressor 1 | 0.0450181 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0445977 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0417158 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0415437 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0409689 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0403606 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0399688 |
| TMSB10 | thymosin beta 10 | 0.0395369 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0394658 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.038892 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.038685 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0385391 |
| GLCCI1 | glucocorticoid induced 1 | 0.0385065 |
| HMGA2 | high mobility group AT-hook 2 | 0.0383405 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0381771 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0377639 |
| CA12 | carbonic anhydrase XII | 0.0360584 |
| NAV2 | neuron navigator 2 | 0.0350941 |
| S100A6 | S100 calcium binding protein A6 | 0.034443 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.033947 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0335537 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0335022 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0329285 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0324274 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0321607 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0320262 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0320258 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0318067 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.031458 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0306239 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0302679 |
| HDAC9 | histone deacetylase 9 | 0.0302468 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0299032 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297912 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0294542 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0294272 |
| LOXL2 | lysyl oxidase-like 2 | 0.0285161 |
| VEGFA | vascular endothelial growth factor A | 0.0278489 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0275943 |
| VMP1 | vacuole membrane protein 1 | 0.0274659 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0268776 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0266579 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0263483 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0260983 |
| B2M | beta-2-microglobulin | 0.0259377 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0258848 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0253655 |
| LDHA | lactate dehydrogenase A | 0.0251927 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0247904 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0247308 |
| NTN4 | netrin 4 | 0.0246825 |
| RCOR1 | REST corepressor 1 | 0.0246819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0246703 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0245786 |
| NOTCH2 | notch 2 | 0.0244435 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0243841 |
| PLIN2 | perilipin 2 | 0.0242372 |
| FLNB | filamin B, beta | 0.0242232 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0242113 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0241313 |
| HMGA1 | high mobility group AT-hook 1 | 0.0240279 |
| FHL2 | four and a half LIM domains 2 | 0.0240025 |
| EFNA5 | ephrin-A5 | 0.0239844 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0239209 |
| RNF24 | ring finger protein 24 | 0.0237612 |
| CCDC88A | coiled-coil domain containing 88A | 0.0236023 |
| NAV1 | neuron navigator 1 | 0.0235439 |
| JMJD1C | jumonji domain containing 1C | 0.0232804 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0232444 |
| ANGPTL4 | angiopoietin-like 4 | 0.0232133 |
| LUZP1 | leucine zipper protein 1 | 0.0231622 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.022995 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0228481 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0228411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142093 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0865596 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0689124 |
| RBM39 | RNA binding motif protein 39 | -0.0566813 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0478789 |
| IER3 | immediate early response 3 | -0.0400673 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0392806 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0386623 |
| TXNRD1 | thioredoxin reductase 1 | -0.0385594 |
| SMAD3 | SMAD family member 3 | -0.0384345 |
| AHNAK | AHNAK nucleoprotein | -0.0346631 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0346017 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0344869 |
| OGA | O-GlcNAcase | -0.0313022 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.031155 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0280321 |
| PARD3 | par-3 family cell polarity regulator | -0.0252816 |
| CANX | calnexin | -0.0249679 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0246813 |
| RPS24 | ribosomal protein S24 | -0.0239438 |
| PTMA | prothymosin, alpha | -0.0230291 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0213955 |
| USP3 | ubiquitin specific peptidase 3 | -0.0209397 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0209142 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0208839 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0202881 |
| H1-0 | H1.0 linker histone | -0.0198617 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0198324 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0196684 |
| EZR | ezrin | -0.0194249 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0192765 |
| YBX1 | Y box binding protein 1 | -0.0192431 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0189285 |
| RRBP1 | ribosome binding protein 1 | -0.0184667 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0183818 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0183548 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0183429 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0181869 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0179994 |
| FRMD5 | FERM domain containing 5 | -0.01795 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.017946 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0177647 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0172224 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.017189 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.016515 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0165095 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0164569 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0163301 |
| PRELID2 | PRELI domain containing 2 | -0.0161665 |
| XPO1 | exportin 1 | -0.0161461 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0160168 |
| FBXO32 | F-box protein 32 | -0.0159988 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0159824 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0157693 |
| FAM20C | family with sequence similarity 20, member C | -0.0157562 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0156051 |
| OLA1 | Obg-like ATPase 1 | -0.0155494 |
| RPLP1 | ribosomal protein, large, P1 | -0.0154991 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0153207 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0151887 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0151118 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0150971 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0149037 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0147847 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0146879 |
| MORF4L2 | mortality factor 4 like 2 | -0.0146605 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0145948 |
| SDC4 | syndecan 4 | -0.014549 |
| SQSTM1 | sequestosome 1 | -0.0144406 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0143286 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0143249 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0142917 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0141534 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0141338 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0139392 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -0.0138854 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0138776 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0138649 |
| RPL38 | ribosomal protein L38 | -0.0138401 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0138195 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0138072 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0137361 |
| RPL4 | ribosomal protein L4 | -0.0136738 |
| TMEM263 | transmembrane protein 263 | -0.0136499 |
| ZNF292 | zinc finger protein 292 | -0.0135715 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0135092 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0134803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0133688 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0127937 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0127623 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0127123 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0125879 |
| CAB39 | calcium binding protein 39 | -0.0125554 |
| TCF12 | transcription factor 12 | -0.0125247 |
| SYT1 | synaptotagmin I | -0.012482 |
| RPS6 | ribosomal protein S6 | -0.0124627 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0124374 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0124086 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0122991 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0122773 |
