| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flutamide_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.115458 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0705479 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0669704 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0595318 |
| SLC38A2 | solute carrier family 38, member 2 | 0.041842 |
| PFN1 | profilin 1 | 0.0407612 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0373183 |
| EGR1 | early growth response 1 | 0.0350556 |
| HDAC9 | histone deacetylase 9 | 0.0346673 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0327795 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0315482 |
| COPA | coatomer protein complex, subunit alpha | 0.0314839 |
| NUP58 | nucleoporin 58 | 0.0310702 |
| VIM | vimentin | 0.0288458 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0279533 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0258794 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0249782 |
| PCBP1 | poly(rC) binding protein 1 | 0.0248089 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0242599 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0235495 |
| FLNA | filamin A, alpha | 0.023386 |
| ERBIN | erbb2 interacting protein | 0.0226038 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0223162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0218663 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0211795 |
| VMP1 | vacuole membrane protein 1 | 0.020848 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0194765 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0190645 |
| HMGA1 | high mobility group AT-hook 1 | 0.0189796 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0185853 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0178427 |
| RBM25 | RNA binding motif protein 25 | 0.0174404 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0173886 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0171756 |
| PCBP2 | poly(rC) binding protein 2 | 0.0163353 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0157973 |
| FGG | fibrinogen gamma chain | 0.0156078 |
| KLF6 | Kruppel-like factor 6 | 0.0155091 |
| RAD51B | RAD51 paralog B | 0.015437 |
| STC1 | stanniocalcin 1 | 0.0152379 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0151807 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0147053 |
| KYNU | kynureninase | 0.014584 |
| KIF5B | kinesin family member 5B | 0.0145769 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0144884 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0143785 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0142035 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0141331 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0140279 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0139696 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0139328 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0137692 |
| TGFB2 | transforming growth factor, beta 2 | 0.0135408 |
| MYO19 | myosin XIX | 0.0134282 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0132903 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0132327 |
| TMEM87A | transmembrane protein 87A | 0.0131691 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0131326 |
| ACTN1 | actinin, alpha 1 | 0.0130128 |
| MKI67 | marker of proliferation Ki-67 | 0.0129738 |
| ACTG1 | actin gamma 1 | 0.0129352 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0123109 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0122889 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0122813 |
| SBF2 | SET binding factor 2 | 0.0122281 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0121076 |
| CCNL1 | cyclin L1 | 0.0120213 |
| RCOR1 | REST corepressor 1 | 0.0119256 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0119117 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0118705 |
| MITF | microphthalmia-associated transcription factor | 0.0117304 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.011545 |
| YTHDC1 | YTH domain containing 1 | 0.0115371 |
| NTN4 | netrin 4 | 0.0114812 |
| PRRC2A | proline-rich coiled-coil 2A | 0.01137 |
| ZNF277 | zinc finger protein 277 | 0.0113532 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0112708 |
| PRR16 | proline rich 16 | 0.0112188 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0111786 |
| FLNB | filamin B, beta | 0.0111699 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0111609 |
| NFIB | nuclear factor I/B | 0.0109851 |
| LDHA | lactate dehydrogenase A | 0.0109841 |
| TBC1D19 | TBC1 domain family, member 19 | 0.0109402 |
| ITGB5 | integrin, beta 5 | 0.0108747 |
| AHR | aryl hydrocarbon receptor | 0.0108622 |
| NUP153 | nucleoporin 153kDa | 0.0108317 |
| RIOK1 | RIO kinase 1 | 0.0106958 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0105537 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.0103557 |
| CHN1 | chimerin 1 | 0.0102915 |
| AUP1 | ancient ubiquitous protein 1 | 0.0102559 |
| LAMA5 | laminin, alpha 5 | 0.0102284 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0101513 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00999789 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00998707 |
| TPR | translocated promoter region, nuclear basket protein | 0.00996912 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.00984161 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00984115 |
| BICC1 | BicC family RNA binding protein 1 | 0.00982649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125238 |
| RPL19 | ribosomal protein L19 | -0.0936531 |
| MT2A | metallothionein 2A | -0.0834609 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0822904 |
| PTMA | prothymosin, alpha | -0.0820804 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0814063 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0794989 |
| IER3 | immediate early response 3 | -0.0783388 |
| RPS21 | ribosomal protein S21 | -0.0672608 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0664258 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0638567 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0620878 |
| FTL | ferritin, light polypeptide | -0.0619139 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0580248 |
| RPS6 | ribosomal protein S6 | -0.0572005 |
| AHNAK | AHNAK nucleoprotein | -0.0561451 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0560074 |
| GRAMD1B | GRAM domain containing 1B | -0.0510762 |
| ASPH | aspartate beta-hydroxylase | -0.0496009 |
| S100A10 | S100 calcium binding protein A10 | -0.0495716 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0491484 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0479098 |
| RPLP1 | ribosomal protein, large, P1 | -0.0451675 |
| RPS25 | ribosomal protein S25 | -0.0448662 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0441569 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0413442 |
| CAVIN1 | caveolae associated protein 1 | -0.0412374 |
| RPS27A | ribosomal protein S27a | -0.0402423 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0399553 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0397305 |
| RPS15 | ribosomal protein S15 | -0.0393107 |
| RPL8 | ribosomal protein L8 | -0.0383403 |
| RBM39 | RNA binding motif protein 39 | -0.037981 |
| CANX | calnexin | -0.0373666 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0371954 |
| RPS23 | ribosomal protein S23 | -0.0370461 |
| RPS8 | ribosomal protein S8 | -0.0321134 |
| RPS16 | ribosomal protein S16 | -0.0319665 |
| RPL38 | ribosomal protein L38 | -0.0312863 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0308661 |
| S100A6 | S100 calcium binding protein A6 | -0.0308521 |
| UBC | ubiquitin C | -0.0305777 |
| DEK | DEK proto-oncogene | -0.0304383 |
| TXNRD1 | thioredoxin reductase 1 | -0.0298114 |
| TPM3 | tropomyosin 3 | -0.0296872 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0296475 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0295442 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0285471 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0283587 |
| SRGN | serglycin | -0.0281436 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0279377 |
| S100A9 | S100 calcium binding protein A9 | -0.0277706 |
| RPS29 | ribosomal protein S29 | -0.0274089 |
| RPS24 | ribosomal protein S24 | -0.0271216 |
| TPI1 | triosephosphate isomerase 1 | -0.0270152 |
| RPS5 | ribosomal protein S5 | -0.0267927 |
| DENND4A | DENN/MADD domain containing 4A | -0.0267593 |
| RPL32 | ribosomal protein L32 | -0.0261385 |
| SERF2 | small EDRK-rich factor 2 | -0.0260624 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0259642 |
| SDC4 | syndecan 4 | -0.0254479 |
| RPS11 | ribosomal protein S11 | -0.0254467 |
| RPL34 | ribosomal protein L34 | -0.0253534 |
| SETD5 | SET domain containing 5 | -0.0252559 |
| FUS | FUS RNA binding protein | -0.0249861 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0249595 |
| RAN | RAN, member RAS oncogene family | -0.024947 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0248231 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0248149 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0245769 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.024407 |
| RPL11 | ribosomal protein L11 | -0.0242898 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0242576 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0236134 |
| RPL7 | ribosomal protein L7 | -0.0234055 |
| USP3 | ubiquitin specific peptidase 3 | -0.0231045 |
| RPL12 | ribosomal protein L12 | -0.0230548 |
| RPLP2 | ribosomal protein, large, P2 | -0.022883 |
| RPL23 | ribosomal protein L23 | -0.0227745 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0226672 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.022494 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0223104 |
| RHEB | Ras homolog enriched in brain | -0.0221722 |
| RPL28 | ribosomal protein L28 | -0.0220667 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0220042 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0217843 |
| ASTN2 | astrotactin 2 | -0.0217741 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0217122 |
| RPLP0 | ribosomal protein, large, P0 | -0.021544 |
| NNMT | nicotinamide N-methyltransferase | -0.0215224 |
| RPL5 | ribosomal protein L5 | -0.0213986 |
| PTK2 | protein tyrosine kinase 2 | -0.0212106 |
| WTAP | Wilms tumor 1 associated protein | -0.0211787 |
| ENO1 | enolase 1, (alpha) | -0.0211475 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0209884 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0209873 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0209319 |
| RPS10 | ribosomal protein S10 | -0.0208739 |
| CD99 | CD99 molecule | -0.0208298 |
