| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0945665 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0845037 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0750409 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.073199 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0653293 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0645152 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.059621 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0586508 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.058365 |
| EHBP1 | EH domain binding protein 1 | 0.0576523 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0542726 |
| KYNU | kynureninase | 0.0520904 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0505412 |
| COPA | coatomer protein complex, subunit alpha | 0.0500829 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0496341 |
| PDE10A | phosphodiesterase 10A | 0.0487489 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0487105 |
| FTL | ferritin, light polypeptide | 0.0484748 |
| LIMA1 | LIM domain and actin binding 1 | 0.0480842 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0468572 |
| PTMA | prothymosin, alpha | 0.0459327 |
| IGF2 | insulin-like growth factor 2 | 0.0455863 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0451905 |
| RPS12 | ribosomal protein S12 | 0.043876 |
| DST | dystonin | 0.0426633 |
| EFNA5 | ephrin-A5 | 0.0421185 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0413685 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0413046 |
| GPC6 | glypican 6 | 0.0404995 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0401926 |
| GLG1 | golgi glycoprotein 1 | 0.040096 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0393507 |
| PARD3 | par-3 family cell polarity regulator | 0.0393004 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0389884 |
| CD44 | CD44 molecule (Indian blood group) | 0.0387732 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0380194 |
| SEPTIN9 | septin 9 | 0.0361597 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.036144 |
| MT2A | metallothionein 2A | 0.0361098 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0359349 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.03561 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0355746 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0351797 |
| USP34 | ubiquitin specific peptidase 34 | 0.0349127 |
| SPAG9 | sperm associated antigen 9 | 0.0344449 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0332196 |
| RPL37A | ribosomal protein L37a | 0.0328017 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325448 |
| RBM39 | RNA binding motif protein 39 | 0.032485 |
| TMSB10 | thymosin beta 10 | 0.0324659 |
| RPS24 | ribosomal protein S24 | 0.0323423 |
| PRKD1 | protein kinase D1 | 0.0318427 |
| RPL36 | ribosomal protein L36 | 0.031794 |
| ZFR | zinc finger RNA binding protein | 0.0313978 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0313376 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0313005 |
| WDR43 | WD repeat domain 43 | 0.0310753 |
| RAD51B | RAD51 paralog B | 0.0308053 |
| RPS3 | ribosomal protein S3 | 0.0308016 |
| S100A11 | S100 calcium binding protein A11 | 0.0307115 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0306964 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0306377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0304545 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0304502 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0304124 |
| CMIP | c-Maf inducing protein | 0.0301863 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0300155 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.029126 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0291216 |
| PGK1 | phosphoglycerate kinase 1 | 0.0287937 |
| SLMAP | sarcolemma associated protein | 0.0287227 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0285379 |
| RPS11 | ribosomal protein S11 | 0.0285244 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0279612 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0277261 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.02767 |
| ANXA2 | annexin A2 | 0.0276261 |
| SERINC1 | serine incorporator 1 | 0.0274757 |
| WWOX | WW domain containing oxidoreductase | 0.0273918 |
| PHF21A | PHD finger protein 21A | 0.0270901 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0267826 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0265556 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0265224 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0264252 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0261613 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0258986 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0258557 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0257962 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0257179 |
| KIAA1958 | KIAA1958 | 0.0256648 |
| SRP54 | signal recognition particle 54kDa | 0.0254543 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.025398 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.025315 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0252586 |
| ANXA1 | annexin A1 | 0.0252143 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0251076 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0250917 |
| RPS19 | ribosomal protein S19 | 0.0249712 |
| KANTR | KDM5C adjacent non-coding transcript | 0.0249356 |
| CLTC | clathrin, heavy chain (Hc) | 0.024766 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.147915 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.143436 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.111336 |
| LMO7 | LIM domain 7 | -0.0942934 |
| FAM13A | family with sequence similarity 13, member A | -0.0768641 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0699459 |
| MXD1 | MAX dimerization protein 1 | -0.0650206 |
| ATOSA | atos homolog A | -0.0648737 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0642049 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0615648 |
| ABHD17C | abhydrolase domain containing 17C | -0.0610658 |
| TMEM165 | transmembrane protein 165 | -0.0610646 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.060885 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0581134 |
| LAMC2 | laminin, gamma 2 | -0.0560606 |
| FBXO11 | F-box protein 11 | -0.0538777 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0527479 |
| RPS15 | ribosomal protein S15 | -0.0516652 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0495354 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0485905 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0480402 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0474638 |
| TJP1 | tight junction protein 1 | -0.0472676 |
| ZNF638 | zinc finger protein 638 | -0.0462993 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0462456 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0461297 |
| RNF145 | ring finger protein 145 | -0.0456065 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0455272 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0452631 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0450004 |
| NPTN | neuroplastin | -0.0449222 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0441379 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0433788 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0429266 |
| KRT17 | keratin 17, type I | -0.0428278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0416436 |
| AHNAK | AHNAK nucleoprotein | -0.0415794 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0410161 |
| MMP1 | matrix metallopeptidase 1 | -0.0408719 |
| NDRG1 | N-myc downstream regulated 1 | -0.0398236 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0396849 |
| CCNI | cyclin I | -0.0396031 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0395258 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0382862 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0379273 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.037798 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0375851 |
| SQSTM1 | sequestosome 1 | -0.0374428 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0374417 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0373156 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0372073 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0371131 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0370419 |
| RPL21 | ribosomal protein L21 | -0.0367811 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0367142 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0365578 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0363864 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0363537 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0361118 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0359024 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0356231 |
| SDCBP | syndecan binding protein (syntenin) | -0.0351605 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0349433 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0348623 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0344074 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0340821 |
| MCL1 | myeloid cell leukemia 1 | -0.0337355 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0336861 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0336388 |
| FOXO3 | forkhead box O3 | -0.0335526 |
| FMNL2 | formin-like 2 | -0.033506 |
| INHBA | inhibin, beta A | -0.0334904 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0334567 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0331525 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0330689 |
| FNBP1L | formin binding protein 1-like | -0.0327113 |
| HDLBP | high density lipoprotein binding protein | -0.0326393 |
| UBC | ubiquitin C | -0.0325096 |
| LAMB3 | laminin, beta 3 | -0.0321263 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0320328 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0319913 |
| KLF6 | Kruppel-like factor 6 | -0.0316953 |
| RPS5 | ribosomal protein S5 | -0.0316594 |
| PARD6B | par-6 family cell polarity regulator beta | -0.031386 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0313542 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.031291 |
| ABHD12 | abhydrolase domain containing 12 | -0.0310074 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0309462 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0308975 |
| SFTPA2 | surfactant protein A2 | -0.0305635 |
| ANXA4 | annexin A4 | -0.0305128 |
| USP53 | ubiquitin specific peptidase 53 | -0.030494 |
| TXNRD1 | thioredoxin reductase 1 | -0.03011 |
| STC1 | stanniocalcin 1 | -0.0299652 |
| LASP1 | LIM and SH3 protein 1 | -0.0299245 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.029922 |
| EGFR | epidermal growth factor receptor | -0.029879 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0296592 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0295898 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0294936 |
