| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.112172 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.109086 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0620348 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0588519 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0515093 |
| IGF2 | insulin-like growth factor 2 | 0.0455913 |
| EGR1 | early growth response 1 | 0.0451238 |
| PFN1 | profilin 1 | 0.0447415 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0349673 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0347446 |
| MKI67 | marker of proliferation Ki-67 | 0.0336735 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.032157 |
| VIM | vimentin | 0.0304392 |
| KLF6 | Kruppel-like factor 6 | 0.0293146 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0288069 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0285402 |
| ACTG1 | actin gamma 1 | 0.0272495 |
| MT2A | metallothionein 2A | 0.0270255 |
| RTN4 | reticulon 4 | 0.0264863 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0261665 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0261213 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0256644 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0255315 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.025074 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.025056 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0247724 |
| PGK1 | phosphoglycerate kinase 1 | 0.0229647 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0226819 |
| TMEM41B | transmembrane protein 41B | 0.0226397 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0224434 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0224259 |
| TPI1 | triosephosphate isomerase 1 | 0.0220243 |
| TWF1 | twinfilin actin binding protein 1 | 0.0217078 |
| OSMR | oncostatin M receptor | 0.0214277 |
| HMGA1 | high mobility group AT-hook 1 | 0.0214013 |
| RACK1 | receptor for activated C kinase 1 | 0.0213267 |
| PCBP1 | poly(rC) binding protein 1 | 0.0212584 |
| NUP58 | nucleoporin 58 | 0.0211086 |
| RPL35A | ribosomal protein L35a | 0.0209199 |
| STC1 | stanniocalcin 1 | 0.0208597 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0204272 |
| KIF5B | kinesin family member 5B | 0.0202328 |
| KRT18 | keratin 18, type I | 0.0198413 |
| RPS2 | ribosomal protein S2 | 0.0197979 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0196628 |
| ANXA5 | annexin A5 | 0.0192266 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0190696 |
| RPS12 | ribosomal protein S12 | 0.0189922 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0188109 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0180472 |
| GRAMD1B | GRAM domain containing 1B | 0.0175952 |
| NCKAP1 | NCK-associated protein 1 | 0.0175234 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.017447 |
| RPLP0 | ribosomal protein, large, P0 | 0.0173851 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0172526 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0172415 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0172361 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0170482 |
| CLTC | clathrin, heavy chain (Hc) | 0.0169765 |
| LATS2 | large tumor suppressor kinase 2 | 0.0167652 |
| ZNF292 | zinc finger protein 292 | 0.0167143 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0166763 |
| RPS27 | ribosomal protein S27 | 0.0165349 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0163143 |
| JMJD1C | jumonji domain containing 1C | 0.0161497 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0160066 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0158136 |
| MT1E | metallothionein 1E | 0.0157543 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0155625 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0153995 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0151353 |
| KLF10 | Kruppel-like factor 10 | 0.0149893 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0144371 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0143045 |
| SET | SET nuclear proto-oncogene | 0.0142751 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0142535 |
| RPL12 | ribosomal protein L12 | 0.0141473 |
| YBX3 | Y box binding protein 3 | 0.0139741 |
| PFDN2 | prefoldin subunit 2 | 0.0139323 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0138597 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0138534 |
| RPL37 | ribosomal protein L37 | 0.013785 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0137796 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0137765 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0136805 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0134654 |
| S100A11 | S100 calcium binding protein A11 | 0.013432 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.013322 |
| MMP12 | matrix metallopeptidase 12 | 0.0132379 |
| BBX | bobby sox homolog (Drosophila) | 0.0129431 |
| RPS14 | ribosomal protein S14 | 0.0129424 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0129315 |
| TNPO3 | transportin 3 | 0.0129307 |
| PYGL | phosphorylase, glycogen, liver | 0.0128903 |
| CCDC88A | coiled-coil domain containing 88A | 0.0126559 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0125301 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0123679 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0123662 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0122435 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0121404 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0818606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0712469 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0671817 |
| UBC | ubiquitin C | -0.0663403 |
| MCL1 | myeloid cell leukemia 1 | -0.0570829 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0562738 |
| AHNAK | AHNAK nucleoprotein | -0.0544497 |
| PTMA | prothymosin, alpha | -0.0516447 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0509553 |
| RBM39 | RNA binding motif protein 39 | -0.0507555 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0503285 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0453123 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0430595 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0370691 |
| RPS27A | ribosomal protein S27a | -0.0365911 |
| AEBP2 | AE binding protein 2 | -0.0362392 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0345072 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0343216 |
| USP34 | ubiquitin specific peptidase 34 | -0.034252 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0340302 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0336275 |
| CANX | calnexin | -0.0317589 |
| GOLGB1 | golgin B1 | -0.0312174 |
| PCBP2 | poly(rC) binding protein 2 | -0.0312013 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.031065 |
| TPM3 | tropomyosin 3 | -0.0310372 |
| INTS6 | integrator complex subunit 6 | -0.0290704 |
| PDE10A | phosphodiesterase 10A | -0.0286699 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0285811 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0281489 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0280147 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0279862 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0279641 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0278786 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0277186 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0270306 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0268027 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0267016 |
| ENO1 | enolase 1, (alpha) | -0.0256986 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0255483 |
| CDK12 | cyclin-dependent kinase 12 | -0.0250914 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0248124 |
| ZNF638 | zinc finger protein 638 | -0.0243224 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0242947 |
| PTK2 | protein tyrosine kinase 2 | -0.0240728 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0232922 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0229477 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0229405 |
| NF1 | neurofibromin 1 | -0.0229295 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0226926 |
| RSF1 | remodeling and spacing factor 1 | -0.0224978 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.022042 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.021916 |
| ATXN1 | ataxin 1 | -0.0218963 |
| WDR70 | WD repeat domain 70 | -0.0218523 |
| SMYD3 | SET and MYND domain containing 3 | -0.0211571 |
| TPM2 | tropomyosin 2 (beta) | -0.0211281 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0209297 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0208759 |
| BRD2 | bromodomain containing 2 | -0.0207244 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0206927 |
| DENND1A | DENN/MADD domain containing 1A | -0.0206848 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0205879 |
| YAP1 | Yes-associated protein 1 | -0.0205782 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0201972 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0201681 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0200849 |
| CTTN | cortactin | -0.0200749 |
| WWOX | WW domain containing oxidoreductase | -0.0198087 |
| VCP | valosin containing protein | -0.0196919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0196718 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0195647 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0195358 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0195203 |
| SRSF5 | serine/arginine-rich splicing factor 5 | -0.0194857 |
| CALR | calreticulin | -0.0194623 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0189297 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.018733 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0187283 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0187251 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.0186366 |
| TAOK1 | TAO kinase 1 | -0.0184616 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0181358 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.017922 |
| RAD51B | RAD51 paralog B | -0.0178577 |
| HMGA2 | high mobility group AT-hook 2 | -0.0177136 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0176868 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0176055 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0175156 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0172752 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0171581 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0171485 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0170624 |
| H1-0 | H1.0 linker histone | -0.0168901 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0167925 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0167116 |
| OGA | O-GlcNAcase | -0.0166934 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0166358 |
| PRELID2 | PRELI domain containing 2 | -0.0166001 |
| RYR3 | ryanodine receptor 3 | -0.0165172 |
