| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.135636 |
| FN1 | fibronectin 1 | 0.123945 |
| VIM | vimentin | 0.0974637 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0900074 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0877421 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0857287 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0845286 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0825759 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0730231 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0651685 |
| PGK1 | phosphoglycerate kinase 1 | 0.0611281 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0590247 |
| TMSB10 | thymosin beta 10 | 0.055215 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0546005 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0533571 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0530793 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0530648 |
| STC1 | stanniocalcin 1 | 0.051112 |
| FTL | ferritin, light polypeptide | 0.0508619 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0494219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0480082 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0456995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0453541 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0442455 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0439731 |
| CTSC | cathepsin C | 0.0431927 |
| KYNU | kynureninase | 0.0429846 |
| MYOF | myoferlin | 0.0411644 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0405266 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0395822 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.039531 |
| GNAS | GNAS complex locus | 0.0394711 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0388115 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0378595 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0371354 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0364173 |
| LDHA | lactate dehydrogenase A | 0.0363501 |
| INHBA | inhibin, beta A | 0.0356363 |
| S100A6 | S100 calcium binding protein A6 | 0.0355712 |
| NDRG1 | N-myc downstream regulated 1 | 0.0349618 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0343894 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0332524 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0322069 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0321299 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0320065 |
| CD109 | CD109 molecule | 0.031771 |
| RPS12 | ribosomal protein S12 | 0.0307804 |
| DNER | delta/notch-like EGF repeat containing | 0.0303222 |
| PFN1 | profilin 1 | 0.0294897 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0294382 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0293801 |
| RPL35A | ribosomal protein L35a | 0.02915 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0289004 |
| RACK1 | receptor for activated C kinase 1 | 0.0286439 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0285218 |
| STC2 | stanniocalcin 2 | 0.0278868 |
| EGR1 | early growth response 1 | 0.0269015 |
| ACTG1 | actin gamma 1 | 0.0263558 |
| MT2A | metallothionein 2A | 0.0261856 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0261674 |
| FLNA | filamin A, alpha | 0.0261067 |
| GDA | guanine deaminase | 0.0260208 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0258471 |
| SPAG9 | sperm associated antigen 9 | 0.0257286 |
| RPS4X | ribosomal protein S4, X-linked | 0.0256551 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0253109 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0252159 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0251603 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0250898 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0247768 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0247589 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.023043 |
| MKI67 | marker of proliferation Ki-67 | 0.0230043 |
| PYGL | phosphorylase, glycogen, liver | 0.0229965 |
| PTEN | phosphatase and tensin homolog | 0.0221204 |
| COPA | coatomer protein complex, subunit alpha | 0.0217602 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.021488 |
| GPRIN3 | GPRIN family member 3 | 0.0214751 |
| TBXT | T-box transcription factor T | 0.0213939 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.021273 |
| EPHA4 | EPH receptor A4 | 0.0212151 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.021065 |
| B2M | beta-2-microglobulin | 0.0210138 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0206641 |
| RIGI | RNA sensor RIG-I | 0.0205954 |
| ARRDC3 | arrestin domain containing 3 | 0.0203304 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0199685 |
| EFNA5 | ephrin-A5 | 0.0198809 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0198344 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0196084 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0194222 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0191035 |
| PCBP1 | poly(rC) binding protein 1 | 0.0189711 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0189431 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0188637 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0186488 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0184882 |
| HLA-A | major histocompatibility complex, class I, A | 0.0182455 |
| FAM13A | family with sequence similarity 13, member A | 0.0182088 |
| ZNF292 | zinc finger protein 292 | 0.018107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.063159 |
| PDE10A | phosphodiesterase 10A | -0.0617534 |
| TXNRD1 | thioredoxin reductase 1 | -0.0498484 |
| CDH13 | cadherin 13 | -0.0485212 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.045112 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0417342 |
| GRAMD1B | GRAM domain containing 1B | -0.0378715 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0376471 |
| AUTS2 | autism susceptibility candidate 2 | -0.0365394 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0364208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0328992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0328015 |
| AHNAK | AHNAK nucleoprotein | -0.03146 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0311519 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0308406 |
| RPS6 | ribosomal protein S6 | -0.0299942 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0297353 |
| LSAMP | limbic system-associated membrane protein | -0.0296442 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0294202 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0284437 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0282195 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0278302 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0276355 |
| PTMA | prothymosin, alpha | -0.0271161 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0259217 |
| CADM2 | cell adhesion molecule 2 | -0.0258948 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0249801 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0247677 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0246353 |
| SMYD3 | SET and MYND domain containing 3 | -0.0241057 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0236501 |
| DENND1A | DENN/MADD domain containing 1A | -0.0227816 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0224672 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0223896 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0217981 |
| RBM39 | RNA binding motif protein 39 | -0.0213697 |
| ASPH | aspartate beta-hydroxylase | -0.0205048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0200977 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0194926 |
| TPM3 | tropomyosin 3 | -0.019131 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0188692 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0188686 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0187693 |
| RPS24 | ribosomal protein S24 | -0.0185972 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0182345 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0180512 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.017889 |
| SQSTM1 | sequestosome 1 | -0.0175953 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0175524 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0172343 |
| XYLT1 | xylosyltransferase I | -0.0172044 |
| EXT1 | exostosin glycosyltransferase 1 | -0.016919 |
| RANBP17 | RAN binding protein 17 | -0.0167307 |
| TENM3 | teneurin transmembrane protein 3 | -0.0167227 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0163938 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0159986 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0159562 |
| PCBP3 | poly(rC) binding protein 3 | -0.0159043 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.015618 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0154718 |
| RAB10 | RAB10, member RAS oncogene family | -0.0154574 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0153478 |
| UBC | ubiquitin C | -0.015343 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0151365 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0150875 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0150652 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0149625 |
| FMNL2 | formin-like 2 | -0.0149269 |
| RHOA | ras homolog family member A | -0.0146863 |
| GOLGB1 | golgin B1 | -0.0146818 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0146584 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0146037 |
| RPL3 | ribosomal protein L3 | -0.0144661 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0143637 |
| RPL38 | ribosomal protein L38 | -0.0142766 |
| RPS21 | ribosomal protein S21 | -0.0140834 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0140491 |
| FUS | FUS RNA binding protein | -0.0139845 |
| CUX1 | cut-like homeobox 1 | -0.013936 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0138027 |
| GPATCH2 | G patch domain containing 2 | -0.0137707 |
| NRXN3 | neurexin 3 | -0.0136879 |
| MED13L | mediator complex subunit 13-like | -0.0136352 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0136043 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0133953 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0131534 |
| INTS6 | integrator complex subunit 6 | -0.0131074 |
| RAD51B | RAD51 paralog B | -0.0130966 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0129636 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0129357 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0127706 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0127081 |
| AEBP2 | AE binding protein 2 | -0.0127053 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0127036 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0126906 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0126568 |
| SRPK2 | SRSF protein kinase 2 | -0.012627 |
| GLCCI1 | glucocorticoid induced 1 | -0.0125954 |
| SEPTIN9 | septin 9 | -0.0125328 |
| NCKAP5 | NCK-associated protein 5 | -0.0123246 |
