| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0835435 |
| SBF2 | SET binding factor 2 | 0.0802838 |
| FTL | ferritin, light polypeptide | 0.0797215 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0776369 |
| SET | SET nuclear proto-oncogene | 0.0741431 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0720929 |
| ZNF292 | zinc finger protein 292 | 0.0640229 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0633874 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0630903 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0630441 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0614684 |
| MEF2A | myocyte enhancer factor 2A | 0.0610745 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0601167 |
| MATR3 | matrin 3 | 0.0585526 |
| RPL11 | ribosomal protein L11 | 0.0581897 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.057589 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.056848 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0556294 |
| XPO1 | exportin 1 | 0.055491 |
| RPL37 | ribosomal protein L37 | 0.0549491 |
| BBX | bobby sox homolog (Drosophila) | 0.0545049 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0544512 |
| DSCAM | Down syndrome cell adhesion molecule | 0.054448 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0542393 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0529827 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.052771 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0523699 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0517216 |
| GPC6 | glypican 6 | 0.0516502 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0506491 |
| SLMAP | sarcolemma associated protein | 0.0501414 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0501163 |
| PCBP2 | poly(rC) binding protein 2 | 0.0499492 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0485924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0469073 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0465721 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0462042 |
| RACK1 | receptor for activated C kinase 1 | 0.0444691 |
| JMJD1C | jumonji domain containing 1C | 0.0440645 |
| TXNRD1 | thioredoxin reductase 1 | 0.0439137 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0435557 |
| FMN1 | formin 1 | 0.0435215 |
| RNF145 | ring finger protein 145 | 0.0429197 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0419818 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0413282 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0409027 |
| NF1 | neurofibromin 1 | 0.0406427 |
| OGA | O-GlcNAcase | 0.0399631 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0391252 |
| HELZ | helicase with zinc finger | 0.0390963 |
| NCOR2 | nuclear receptor corepressor 2 | 0.038895 |
| USP3 | ubiquitin specific peptidase 3 | 0.0377988 |
| CD109 | CD109 molecule | 0.0372982 |
| MED13L | mediator complex subunit 13-like | 0.0368512 |
| RPL31 | ribosomal protein L31 | 0.0364347 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0355532 |
| TMEM123 | transmembrane protein 123 | 0.0354792 |
| TPR | translocated promoter region, nuclear basket protein | 0.035094 |
| GNAS | GNAS complex locus | 0.0348908 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0342871 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0334491 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0333035 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0323358 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0312217 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0303074 |
| PTK2 | protein tyrosine kinase 2 | 0.0298496 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0297149 |
| VMP1 | vacuole membrane protein 1 | 0.0296219 |
| ACTG1 | actin gamma 1 | 0.0295425 |
| ANXA2 | annexin A2 | 0.0291905 |
| ZNF148 | zinc finger protein 148 | 0.0286826 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0282787 |
| LDHA | lactate dehydrogenase A | 0.0277842 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0268592 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0268229 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0266753 |
| RPLP1 | ribosomal protein, large, P1 | 0.0257473 |
| RPS12 | ribosomal protein S12 | 0.0253712 |
| NDRG1 | N-myc downstream regulated 1 | 0.0252456 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0244747 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0240732 |
| SQSTM1 | sequestosome 1 | 0.0235379 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0233796 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0224735 |
| RTN4 | reticulon 4 | 0.0224549 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0222737 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0216307 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0208585 |
| PGK1 | phosphoglycerate kinase 1 | 0.0205832 |
| RPS3 | ribosomal protein S3 | 0.0202187 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0193696 |
| PDE10A | phosphodiesterase 10A | 0.0193081 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0189982 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0186675 |
| ZNF638 | zinc finger protein 638 | 0.0167828 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0161138 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0158493 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0148734 |
| EGFR | epidermal growth factor receptor | 0.0143922 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0140662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.214033 |
| EXT1 | exostosin glycosyltransferase 1 | -0.152333 |
| HMGA2 | high mobility group AT-hook 2 | -0.138233 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126881 |
| CDH13 | cadherin 13 | -0.103123 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0951336 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0942789 |
| FN1 | fibronectin 1 | -0.0936835 |
| NAV2 | neuron navigator 2 | -0.0915092 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0898988 |
| ASPH | aspartate beta-hydroxylase | -0.0828971 |
| LMO7 | LIM domain 7 | -0.0826558 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0789106 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.07448 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0701434 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0698879 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0692386 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.067269 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0613048 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0595146 |
| PRKCA | protein kinase C, alpha | -0.0588815 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0587017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0583564 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0577949 |
| TPM4 | tropomyosin 4 | -0.0567282 |
| DIAPH2 | diaphanous-related formin 2 | -0.0494315 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0492425 |
| INHBA | inhibin, beta A | -0.0473164 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0467684 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0455163 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0439436 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0438305 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0435398 |
| VCL | vinculin | -0.0430656 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0430071 |
| RPS25 | ribosomal protein S25 | -0.0425969 |
| VIM | vimentin | -0.0418303 |
| RPL35A | ribosomal protein L35a | -0.041586 |
| TNS3 | tensin 3 | -0.0413616 |
| SMYD3 | SET and MYND domain containing 3 | -0.0411612 |
| ENO1 | enolase 1, (alpha) | -0.0410538 |
| CANX | calnexin | -0.0394847 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0392982 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0391585 |
| GRAMD1B | GRAM domain containing 1B | -0.0389812 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0387819 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0374325 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0367476 |
| FRMD4A | FERM domain containing 4A | -0.0363674 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0344404 |
| LAMB3 | laminin, beta 3 | -0.0339657 |
| LAMA4 | laminin, alpha 4 | -0.0337482 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0324673 |
| CDK6 | cyclin-dependent kinase 6 | -0.0315289 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0308216 |
| RPS19 | ribosomal protein S19 | -0.029698 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0290057 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0288324 |
| MED13 | mediator complex subunit 13 | -0.028613 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0275987 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0274764 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.027325 |
| FMNL2 | formin-like 2 | -0.027267 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0272556 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.025739 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0252073 |
| MCL1 | myeloid cell leukemia 1 | -0.0236992 |
| MSN | moesin | -0.0233542 |
| USP34 | ubiquitin specific peptidase 34 | -0.0232916 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0227223 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0225983 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0219615 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0219446 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0217847 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0217336 |
| MT2A | metallothionein 2A | -0.0201845 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0201397 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0200073 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0195277 |
| RPS6 | ribosomal protein S6 | -0.019499 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0185709 |
| DST | dystonin | -0.0185514 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0181206 |
| TMSB10 | thymosin beta 10 | -0.0179768 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0174761 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0174516 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.017001 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0168326 |
| RPL34 | ribosomal protein L34 | -0.0159219 |
| PTMA | prothymosin, alpha | -0.0153047 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0150996 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.015019 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0147237 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0140232 |
| RUNX1 | runt-related transcription factor 1 | -0.0138632 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0130221 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0128675 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0115421 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.011064 |
| MYO1E | myosin IE | -0.0104964 |
