| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.169429 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.123707 |
| CD44 | CD44 molecule (Indian blood group) | 0.123107 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.109346 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.105271 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0869921 |
| LDHA | lactate dehydrogenase A | 0.0739266 |
| NDRG1 | N-myc downstream regulated 1 | 0.067003 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0650084 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0638045 |
| PDE10A | phosphodiesterase 10A | 0.0622909 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0615209 |
| VCAN | versican | 0.0612384 |
| FN1 | fibronectin 1 | 0.0604198 |
| RPS12 | ribosomal protein S12 | 0.0574317 |
| LOX | lysyl oxidase | 0.0573818 |
| HDAC9 | histone deacetylase 9 | 0.0572686 |
| PGK1 | phosphoglycerate kinase 1 | 0.0545971 |
| STC1 | stanniocalcin 1 | 0.0495462 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0488123 |
| VCL | vinculin | 0.0483403 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0476588 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0466513 |
| FLNB | filamin B, beta | 0.0465136 |
| JMJD1C | jumonji domain containing 1C | 0.0442522 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0436457 |
| SFTPA2 | surfactant protein A2 | 0.0425218 |
| MKI67 | marker of proliferation Ki-67 | 0.0421184 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0420182 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0418832 |
| C3 | complement component 3 | 0.0414648 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0414006 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0410207 |
| EGR1 | early growth response 1 | 0.0394756 |
| ARRDC3 | arrestin domain containing 3 | 0.0384327 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0370926 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0370496 |
| STC2 | stanniocalcin 2 | 0.036107 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0356328 |
| ADM | adrenomedullin | 0.034303 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0339438 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0335064 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0332644 |
| MYOF | myoferlin | 0.0331645 |
| FLNA | filamin A, alpha | 0.0325097 |
| NAV2 | neuron navigator 2 | 0.0322688 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0321346 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0320358 |
| FRMD4A | FERM domain containing 4A | 0.0317413 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0313573 |
| LOXL2 | lysyl oxidase-like 2 | 0.0308431 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.030798 |
| PLIN2 | perilipin 2 | 0.0305063 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0298395 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0297824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0296089 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.029446 |
| KLF6 | Kruppel-like factor 6 | 0.0291545 |
| RNF213 | ring finger protein 213 | 0.0286561 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0282372 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0277441 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0271055 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0270339 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0268173 |
| PLPP6 | phospholipid phosphatase 6 | 0.0265593 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0265493 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0265014 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0261617 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0261266 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0257546 |
| CTSD | cathepsin D | 0.0254179 |
| EGFR | epidermal growth factor receptor | 0.0252436 |
| HLA-A | major histocompatibility complex, class I, A | 0.0250148 |
| ZNF292 | zinc finger protein 292 | 0.0248932 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0246623 |
| RNF24 | ring finger protein 24 | 0.0240468 |
| KYNU | kynureninase | 0.0239227 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0236868 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0236476 |
| ARFGEF3 | ARFGEF family member 3 | 0.0235958 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0231411 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0231202 |
| FTL | ferritin, light polypeptide | 0.0230292 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0227354 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0227058 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0223068 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0222634 |
| OSMR | oncostatin M receptor | 0.0221995 |
| PRELID2 | PRELI domain containing 2 | 0.0220688 |
| CENPF | centromere protein F, 350/400kDa | 0.0220365 |
| TGM2 | transglutaminase 2 | 0.021858 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0218241 |
| ATXN1 | ataxin 1 | 0.0215197 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0215055 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0209291 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0209154 |
| GRN | granulin | 0.0208582 |
| DST | dystonin | 0.0207599 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0206588 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0206458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0966054 |
| IER3 | immediate early response 3 | -0.0956757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.085851 |
| RPS6 | ribosomal protein S6 | -0.0817896 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0744641 |
| RPS24 | ribosomal protein S24 | -0.0713765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.069907 |
| AHNAK | AHNAK nucleoprotein | -0.0690886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0623811 |
| PTMA | prothymosin, alpha | -0.0536479 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0488493 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0430999 |
| CANX | calnexin | -0.040566 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0384213 |
| DEK | DEK proto-oncogene | -0.0378533 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0357479 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0353276 |
| RBM39 | RNA binding motif protein 39 | -0.0348546 |
| SDC4 | syndecan 4 | -0.0344583 |
| OGA | O-GlcNAcase | -0.0340484 |
| RPLP2 | ribosomal protein, large, P2 | -0.0336871 |
| RPS21 | ribosomal protein S21 | -0.0333067 |
| SRGN | serglycin | -0.0329883 |
| RPL19 | ribosomal protein L19 | -0.0326431 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0323011 |
| RPS23 | ribosomal protein S23 | -0.0312062 |
| WTAP | Wilms tumor 1 associated protein | -0.0307226 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0298204 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0295535 |
| RPL38 | ribosomal protein L38 | -0.0292943 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0290029 |
| CDH13 | cadherin 13 | -0.0285115 |
| FUS | FUS RNA binding protein | -0.0281029 |
| POTEF | POTE ankyrin domain family, member F | -0.0274539 |
| QKI | QKI, KH domain containing, RNA binding | -0.0272999 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0272258 |
| RRBP1 | ribosome binding protein 1 | -0.0271513 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0268225 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0258392 |
| RPS10 | ribosomal protein S10 | -0.0255738 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0249137 |
| RPL32 | ribosomal protein L32 | -0.0242568 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0241769 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0241238 |
| TPM1 | tropomyosin 1 (alpha) | -0.0240187 |
| RPL26 | ribosomal protein L26 | -0.0238807 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0238697 |
| ASPH | aspartate beta-hydroxylase | -0.0236268 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.02349 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0231387 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0229927 |
| RPS27A | ribosomal protein S27a | -0.0225825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225257 |
| RPS25 | ribosomal protein S25 | -0.0223384 |
| TAOK1 | TAO kinase 1 | -0.0222962 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0222954 |
| HDLBP | high density lipoprotein binding protein | -0.0220962 |
| UBC | ubiquitin C | -0.0217367 |
| RPS8 | ribosomal protein S8 | -0.0216524 |
| RPS13 | ribosomal protein S13 | -0.0215328 |
| CLINT1 | clathrin interactor 1 | -0.0212149 |
| TKT | transketolase | -0.0211565 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0209834 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0208194 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0207908 |
| ANXA2 | annexin A2 | -0.0207871 |
| RPL8 | ribosomal protein L8 | -0.0207578 |
| RPL36A | ribosomal protein L36a | -0.0206614 |
| TXNIP | thioredoxin interacting protein | -0.0206095 |
| RPL14 | ribosomal protein L14 | -0.0204099 |
| COL1A1 | collagen, type I, alpha 1 | -0.0201273 |
| TXNRD1 | thioredoxin reductase 1 | -0.0200175 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0199395 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0199287 |
| HMGB1 | high mobility group box 1 | -0.0197936 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0197607 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0192822 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0191342 |
| RHEB | Ras homolog enriched in brain | -0.0189982 |
| RPL6 | ribosomal protein L6 | -0.0186332 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.018491 |
| RPLP1 | ribosomal protein, large, P1 | -0.0183964 |
| CAVIN1 | caveolae associated protein 1 | -0.0183046 |
| RLF | rearranged L-myc fusion | -0.0182923 |
| SQSTM1 | sequestosome 1 | -0.0182117 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0179982 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0178804 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0178532 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0177927 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0177601 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.017626 |
| MATR3 | matrin 3 | -0.0175617 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0174801 |
| USP3 | ubiquitin specific peptidase 3 | -0.0174276 |
| RPL28 | ribosomal protein L28 | -0.0172934 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.017264 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0171497 |
| OPTN | optineurin | -0.0171495 |
| MED13L | mediator complex subunit 13-like | -0.0170922 |
| RPS16 | ribosomal protein S16 | -0.0170276 |
