| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Flutamide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.140756 |
| NDRG1 | N-myc downstream regulated 1 | 0.0826693 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0819741 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0745521 |
| MT2A | metallothionein 2A | 0.0612756 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0601816 |
| FAM13A | family with sequence similarity 13, member A | 0.0542774 |
| LOX | lysyl oxidase | 0.0512537 |
| ARRDC3 | arrestin domain containing 3 | 0.0501952 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0500168 |
| ATP13A3 | ATPase type 13A3 | 0.0481679 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0449994 |
| LOXL2 | lysyl oxidase-like 2 | 0.0447219 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0435458 |
| ZNF292 | zinc finger protein 292 | 0.0414781 |
| GOLGA4 | golgin A4 | 0.038714 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0386428 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0359172 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0353399 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0348987 |
| SPAG9 | sperm associated antigen 9 | 0.0344614 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0298516 |
| HIP1 | huntingtin interacting protein 1 | 0.0290453 |
| RLF | rearranged L-myc fusion | 0.0282348 |
| COG5 | component of oligomeric golgi complex 5 | 0.0281174 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0276022 |
| STC1 | stanniocalcin 1 | 0.027049 |
| CLINT1 | clathrin interactor 1 | 0.0269012 |
| SFTPA2 | surfactant protein A2 | 0.0266247 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0265576 |
| FOXJ3 | forkhead box J3 | 0.0265166 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0265134 |
| MATR3 | matrin 3 | 0.0260828 |
| TPR | translocated promoter region, nuclear basket protein | 0.025828 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0250532 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0242097 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0237969 |
| ADM | adrenomedullin | 0.0237482 |
| HDLBP | high density lipoprotein binding protein | 0.0236012 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0235096 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0234875 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0233331 |
| TFG | TRK-fused gene | 0.0231155 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0231068 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0220073 |
| SRP54 | signal recognition particle 54kDa | 0.0217994 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0210969 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0209187 |
| COPA | coatomer protein complex, subunit alpha | 0.0207913 |
| YTHDC1 | YTH domain containing 1 | 0.0204985 |
| RBM39 | RNA binding motif protein 39 | 0.0203957 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0203258 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0202449 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0201916 |
| WTAP | Wilms tumor 1 associated protein | 0.0201079 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0199727 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0197472 |
| SGCE | sarcoglycan, epsilon | 0.0196936 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0195638 |
| CD109 | CD109 molecule | 0.019198 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0189855 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0187621 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0186445 |
| KLHDC10 | kelch domain containing 10 | 0.0183761 |
| SUCO | SUN domain containing ossification factor | 0.0183144 |
| RPS2 | ribosomal protein S2 | 0.0182659 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0181904 |
| SFXN1 | sideroflexin 1 | 0.0181864 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0180832 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0180708 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0179446 |
| FMNL2 | formin-like 2 | 0.0179008 |
| MORF4L2 | mortality factor 4 like 2 | 0.0178944 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.017891 |
| FAM13B | family with sequence similarity 13, member B | 0.017701 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0174463 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0174327 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0170874 |
| ANO6 | anoctamin 6 | 0.0170178 |
| CCNI | cyclin I | 0.0169474 |
| GOLT1B | golgi transport 1B | 0.0168748 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0167704 |
| ECE1 | endothelin converting enzyme 1 | 0.0166968 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0166092 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0165898 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0165069 |
| TMEM41B | transmembrane protein 41B | 0.0164725 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0163786 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0160024 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0159541 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0158264 |
| RINT1 | RAD50 interactor 1 | 0.0158261 |
| SCARB2 | scavenger receptor class B, member 2 | 0.015773 |
| GPR107 | G protein-coupled receptor 107 | 0.0155981 |
| FRMD6 | FERM domain containing 6 | 0.0155901 |
| SEC24D | SEC24 family member D | 0.0155513 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0155396 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0153828 |
| MTF2 | metal response element binding transcription factor 2 | 0.0151944 |
| ZNF217 | zinc finger protein 217 | 0.0151544 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.154657 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0914033 |
| POTEF | POTE ankyrin domain family, member F | -0.0810197 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0686206 |
| CALD1 | caldesmon 1 | -0.0640609 |
| VCL | vinculin | -0.0622021 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0603646 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0598715 |
| CDH13 | cadherin 13 | -0.0545058 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0531415 |
| VEGFA | vascular endothelial growth factor A | -0.0511146 |
| MAP1B | microtubule-associated protein 1B | -0.0492835 |
| ENO1 | enolase 1, (alpha) | -0.0482984 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.047822 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.045929 |
| TMSB10 | thymosin beta 10 | -0.0446173 |
| NAV1 | neuron navigator 1 | -0.0438815 |
| TPM1 | tropomyosin 1 (alpha) | -0.0437143 |
| TNS3 | tensin 3 | -0.040813 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0402249 |
| VIM | vimentin | -0.0401868 |
| CDK6 | cyclin-dependent kinase 6 | -0.0386783 |
| FN1 | fibronectin 1 | -0.0377423 |
| IL6 | interleukin 6 | -0.0377098 |
| PRSS23 | protease, serine, 23 | -0.0350756 |
| TMEM165 | transmembrane protein 165 | -0.0338435 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0330457 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0317314 |
| HMGA2 | high mobility group AT-hook 2 | -0.031666 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0298789 |
| COL1A1 | collagen, type I, alpha 1 | -0.0298418 |
| COL5A1 | collagen, type V, alpha 1 | -0.0296096 |
| GOLGB1 | golgin B1 | -0.0293182 |
| VEGFC | vascular endothelial growth factor C | -0.0284895 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0277667 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0275362 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0271781 |
| INTS6 | integrator complex subunit 6 | -0.0260737 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0260406 |
| SEPTIN7 | septin 7 | -0.0258858 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0258405 |
| KAZN | kazrin, periplakin interacting protein | -0.0251445 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0251218 |
| HLA-B | major histocompatibility complex, class I, B | -0.0250115 |
| COL7A1 | collagen, type VII, alpha 1 | -0.024983 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.024893 |
| RASAL2 | RAS protein activator like 2 | -0.024769 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0236542 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0236091 |
| GLIS3 | GLIS family zinc finger 3 | -0.0230025 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0225688 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0224834 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0223211 |
| MT1X | metallothionein 1X | -0.0221783 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0220449 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0219733 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0217891 |
| COL1A2 | collagen, type I, alpha 2 | -0.0216338 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0215624 |
| PKM | pyruvate kinase, muscle | -0.0215623 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0214849 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0210461 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0208146 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0206777 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0205855 |
| MGLL | monoglyceride lipase | -0.0200656 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0198351 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0198014 |
| AUTS2 | autism susceptibility candidate 2 | -0.019529 |
| TPM4 | tropomyosin 4 | -0.0187491 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0187357 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0185996 |
| RHOA | ras homolog family member A | -0.0185071 |
| BRD4 | bromodomain containing 4 | -0.0182828 |
| HLA-A | major histocompatibility complex, class I, A | -0.0182072 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0179688 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0178791 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0177895 |
| IL7R | interleukin 7 receptor | -0.0176936 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0172311 |
| FRMD4A | FERM domain containing 4A | -0.0170778 |
| LDHA | lactate dehydrogenase A | -0.0170708 |
| MYADM | myeloid-associated differentiation marker | -0.0169916 |
| MAP4 | microtubule-associated protein 4 | -0.0169913 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0167403 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.016688 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0165808 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0161227 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0160517 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0159964 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0158449 |
| TAOK1 | TAO kinase 1 | -0.015779 |
| UBE3C | ubiquitin protein ligase E3C | -0.0156813 |
| LMNA | lamin A/C | -0.0155478 |
| MED13 | mediator complex subunit 13 | -0.0154634 |
| ARF4 | ADP-ribosylation factor 4 | -0.0154338 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0153979 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0153756 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0153675 |
| CLMP | CXADR-like membrane protein | -0.0153471 |
