| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Flutamide perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Flutamide_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0772218 |
| ZNF292 | zinc finger protein 292 | 0.0723297 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0602596 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0598115 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0586647 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0551576 |
| ATP13A3 | ATPase type 13A3 | 0.0524693 |
| SET | SET nuclear proto-oncogene | 0.0492996 |
| ATXN1 | ataxin 1 | 0.0444694 |
| CD44 | CD44 molecule (Indian blood group) | 0.0443938 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0442352 |
| DNER | delta/notch-like EGF repeat containing | 0.0439761 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0426711 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0417543 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0409879 |
| CUL5 | cullin 5 | 0.0399693 |
| MKI67 | marker of proliferation Ki-67 | 0.0390849 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0390698 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0385728 |
| SMAD5 | SMAD family member 5 | 0.0382006 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0372079 |
| FLNB | filamin B, beta | 0.0370186 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0345986 |
| MT2A | metallothionein 2A | 0.0342848 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0342661 |
| NAV2 | neuron navigator 2 | 0.0337351 |
| ATP11B | ATPase, class VI, type 11B | 0.0324704 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.032244 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.032199 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0321504 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0319758 |
| RPS2 | ribosomal protein S2 | 0.0319082 |
| SNX13 | sorting nexin 13 | 0.031908 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0314114 |
| SEPTIN2 | septin 2 | 0.0314027 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0311342 |
| YBX3 | Y box binding protein 3 | 0.031051 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0305407 |
| TPR | translocated promoter region, nuclear basket protein | 0.0300728 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0297232 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0292151 |
| DTNA | dystrobrevin, alpha | 0.0292104 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0290679 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0288418 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0285448 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0283625 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0278065 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0267708 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0267653 |
| CCNB1 | cyclin B1 | 0.0267185 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0266646 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0266025 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0265599 |
| ARRDC3 | arrestin domain containing 3 | 0.0265415 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0265293 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0263958 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0263553 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0260763 |
| CENPF | centromere protein F, 350/400kDa | 0.0258571 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0257379 |
| CLTC | clathrin, heavy chain (Hc) | 0.0256306 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0253802 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0252517 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0252446 |
| PYGL | phosphorylase, glycogen, liver | 0.0250046 |
| ITGAV | integrin, alpha V | 0.0248985 |
| PREPL | prolyl endopeptidase-like | 0.0247977 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0247934 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0247535 |
| CCDC88A | coiled-coil domain containing 88A | 0.0247123 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0245935 |
| TPX2 | TPX2, microtubule-associated | 0.0243775 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024039 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0239808 |
| RTN4 | reticulon 4 | 0.023968 |
| OSMR | oncostatin M receptor | 0.0239018 |
| FOXJ3 | forkhead box J3 | 0.023832 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0236901 |
| SSR1 | signal sequence receptor, alpha | 0.0236455 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0235382 |
| GPATCH2L | G patch domain containing 2-like | 0.0235003 |
| CREBRF | CREB3 regulatory factor | 0.0234973 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0234718 |
| RNF145 | ring finger protein 145 | 0.0231773 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0230053 |
| RBM33 | RNA binding motif protein 33 | 0.0229692 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0229585 |
| RPS12 | ribosomal protein S12 | 0.0229435 |
| BRD4 | bromodomain containing 4 | 0.0228949 |
| KIF18B | kinesin family member 18B | 0.0228245 |
| CAPRIN2 | caprin family member 2 | 0.0223285 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0223203 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0222041 |
| COX10 | COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor | 0.022188 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0221492 |
| DYM | dymeclin | 0.0220872 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0220824 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0220729 |
| ACTN1 | actinin, alpha 1 | 0.0218997 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0218474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.297471 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.140777 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.127335 |
| PTMA | prothymosin, alpha | -0.104525 |
| GNAS | GNAS complex locus | -0.0893718 |
| AHNAK | AHNAK nucleoprotein | -0.0847138 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0821167 |
| ANXA2 | annexin A2 | -0.0642502 |
| TMSB10 | thymosin beta 10 | -0.0614955 |
| IER3 | immediate early response 3 | -0.0587123 |
| SQSTM1 | sequestosome 1 | -0.0578955 |
| GOLGA4 | golgin A4 | -0.0539979 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0528636 |
| RPS23 | ribosomal protein S23 | -0.0471443 |
| PARD3 | par-3 family cell polarity regulator | -0.0465787 |
| UBC | ubiquitin C | -0.0465281 |
| SDC4 | syndecan 4 | -0.0464942 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0443237 |
| CAVIN1 | caveolae associated protein 1 | -0.0443012 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0432677 |
| RPS29 | ribosomal protein S29 | -0.041774 |
| CANX | calnexin | -0.0417683 |
| RBM39 | RNA binding motif protein 39 | -0.0416629 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0411984 |
| VIM | vimentin | -0.0411837 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.04072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.039306 |
| RPLP1 | ribosomal protein, large, P1 | -0.0386184 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.037836 |
| SETX | senataxin | -0.0368657 |
| CDK12 | cyclin-dependent kinase 12 | -0.0368611 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0368145 |
| RPS24 | ribosomal protein S24 | -0.0364011 |
| RPS13 | ribosomal protein S13 | -0.0360016 |
| S100A10 | S100 calcium binding protein A10 | -0.0358487 |
| RPS8 | ribosomal protein S8 | -0.0356903 |
| RPL32 | ribosomal protein L32 | -0.035665 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0348577 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034208 |
| HMGA2 | high mobility group AT-hook 2 | -0.0340053 |
| FUS | FUS RNA binding protein | -0.0337701 |
| UBB | ubiquitin B | -0.033644 |
| SMYD3 | SET and MYND domain containing 3 | -0.0330936 |
| PTK2 | protein tyrosine kinase 2 | -0.0330935 |
| RPL11 | ribosomal protein L11 | -0.0329961 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0327448 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0326447 |
| OXSR1 | oxidative stress responsive 1 | -0.032219 |
| ZNF609 | zinc finger protein 609 | -0.0322129 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.031933 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0315978 |
| RIGI | RNA sensor RIG-I | -0.0315766 |
| RPS15 | ribosomal protein S15 | -0.0315142 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0311233 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.031004 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0310024 |
| DEK | DEK proto-oncogene | -0.0309432 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0308732 |
| GPHN | gephyrin | -0.0308431 |
| RPS21 | ribosomal protein S21 | -0.0306577 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0305142 |
| RPL36 | ribosomal protein L36 | -0.0303801 |
| NLK | nemo-like kinase | -0.0301072 |
| H3-3B | H3.3 histone B | -0.0301012 |
| RPL4 | ribosomal protein L4 | -0.0299934 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.029673 |
| S100A9 | S100 calcium binding protein A9 | -0.0296656 |
| RPLP0 | ribosomal protein, large, P0 | -0.0296424 |
| RPL12 | ribosomal protein L12 | -0.0295851 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0288843 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0287642 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0285629 |
| FOXO3 | forkhead box O3 | -0.0282701 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0282139 |
| RPS27A | ribosomal protein S27a | -0.0280334 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0278641 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278077 |
| OGA | O-GlcNAcase | -0.027783 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0277564 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0273343 |
| DST | dystonin | -0.0272541 |
| HMGB1 | high mobility group box 1 | -0.0267721 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0266521 |
| RPL31 | ribosomal protein L31 | -0.0266022 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0261739 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0259233 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0258972 |
| SVIL | supervillin | -0.025832 |
| LMNA | lamin A/C | -0.0258287 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0255303 |
| PRKCA | protein kinase C, alpha | -0.0254271 |
| SSH2 | slingshot protein phosphatase 2 | -0.0251261 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0250396 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0249942 |
| TAOK1 | TAO kinase 1 | -0.0249734 |
| RPS20 | ribosomal protein S20 | -0.0249627 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0243053 |
| RPL19 | ribosomal protein L19 | -0.0243002 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0242399 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.024135 |