| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.139519 |
| CD44 | CD44 molecule (Indian blood group) | 0.116895 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.113337 |
| MAP1B | microtubule-associated protein 1B | 0.102884 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0931566 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.083661 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0734076 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0656742 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0613555 |
| MT2A | metallothionein 2A | 0.0598497 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0583166 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0573856 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0572987 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0562922 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0561766 |
| B2M | beta-2-microglobulin | 0.0559263 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0542972 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0535937 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0526996 |
| FLNA | filamin A, alpha | 0.0500032 |
| MSN | moesin | 0.04889 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0484769 |
| HDAC9 | histone deacetylase 9 | 0.0484155 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0458468 |
| ASPH | aspartate beta-hydroxylase | 0.0449924 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0444564 |
| APP | amyloid beta (A4) precursor protein | 0.0436727 |
| VEGFC | vascular endothelial growth factor C | 0.0436601 |
| MB21D2 | Mab-21 domain containing 2 | 0.042536 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0405191 |
| TPM3 | tropomyosin 3 | 0.0394228 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0377975 |
| PLAT | plasminogen activator, tissue | 0.0371578 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0351567 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0341944 |
| SMAD3 | SMAD family member 3 | 0.0340661 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0338479 |
| RRM2 | ribonucleotide reductase M2 | 0.0333989 |
| E2F7 | E2F transcription factor 7 | 0.0324809 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0324068 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0309555 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0302677 |
| ENO1 | enolase 1, (alpha) | 0.0301072 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0290086 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0286885 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0285711 |
| TOP1 | topoisomerase (DNA) I | 0.0285529 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0285362 |
| SET | SET nuclear proto-oncogene | 0.028483 |
| PDLIM5 | PDZ and LIM domain 5 | 0.028326 |
| PLEC | plectin | 0.0277389 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0271242 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0261881 |
| PCBP2 | poly(rC) binding protein 2 | 0.026071 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0258324 |
| SP100 | SP100 nuclear antigen | 0.0256815 |
| LDHA | lactate dehydrogenase A | 0.0255238 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0253656 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0250059 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0250015 |
| DNMBP | dynamin binding protein | 0.024802 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0246717 |
| PODXL | podocalyxin-like | 0.0246634 |
| DSPP | dentin sialophosphoprotein | 0.0245549 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0244706 |
| SON | SON DNA binding protein | 0.0243431 |
| ITGA6 | integrin, alpha 6 | 0.0242761 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0241039 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.02391 |
| TPR | translocated promoter region, nuclear basket protein | 0.0235371 |
| CLIC1 | chloride intracellular channel 1 | 0.023439 |
| CSTB | cystatin B (stefin B) | 0.0233213 |
| TMSB4X | thymosin beta 4, X-linked | 0.0231722 |
| RAI1 | retinoic acid induced 1 | 0.0231609 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0228937 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0228909 |
| ZNF638 | zinc finger protein 638 | 0.022636 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0225027 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0221974 |
| CORO1C | coronin, actin binding protein, 1C | 0.021839 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0217776 |
| SYNJ2 | synaptojanin 2 | 0.0216798 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0216203 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0215385 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0215015 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.021265 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0211173 |
| EZR | ezrin | 0.0210852 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0210531 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0209142 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0209006 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0208576 |
| CD59 | CD59 molecule, complement regulatory protein | 0.020855 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0202573 |
| DST | dystonin | 0.0202559 |
| NEK7 | NIMA-related kinase 7 | 0.020043 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0198716 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0198345 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0195915 |
| MYO10 | myosin X | 0.0195214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.214375 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.204432 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.143088 |
| LOX | lysyl oxidase | -0.136429 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.127144 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0993002 |
| FBN1 | fibrillin 1 | -0.0953363 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0902194 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0824298 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0814884 |
| LOXL2 | lysyl oxidase-like 2 | -0.0801981 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0798907 |
| COL5A1 | collagen, type V, alpha 1 | -0.0795553 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0770124 |
| NDRG1 | N-myc downstream regulated 1 | -0.0711358 |
| POTEF | POTE ankyrin domain family, member F | -0.0647663 |
| COL5A2 | collagen, type V, alpha 2 | -0.0635002 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0628674 |
| AUTS2 | autism susceptibility candidate 2 | -0.0611413 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0603121 |
| JAZF1 | JAZF zinc finger 1 | -0.0579628 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0577682 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0576937 |
| UBC | ubiquitin C | -0.05508 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0549818 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0531513 |
| EGFR | epidermal growth factor receptor | -0.052912 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0527437 |
| CD99 | CD99 molecule | -0.0527099 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0522184 |
| COL1A2 | collagen, type I, alpha 2 | -0.0521141 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0514315 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0497523 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0497431 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0494115 |
| ACTG1 | actin gamma 1 | -0.0480322 |
| ANXA2 | annexin A2 | -0.0444167 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0433497 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0431339 |
| HDLBP | high density lipoprotein binding protein | -0.0427978 |
| CCND1 | cyclin D1 | -0.0424906 |
| SQSTM1 | sequestosome 1 | -0.0420981 |
| TNS3 | tensin 3 | -0.0419717 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0418453 |
| SPAG9 | sperm associated antigen 9 | -0.0417623 |
| HLA-E | major histocompatibility complex, class I, E | -0.0416366 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0414151 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0410328 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380575 |
| COL3A1 | collagen, type III, alpha 1 | -0.0375868 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0373688 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0368662 |
| TAGLN2 | transgelin 2 | -0.0367702 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.036028 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0350515 |
| MSI2 | musashi RNA-binding protein 2 | -0.0342208 |
| RIGI | RNA sensor RIG-I | -0.0337765 |
| MMP12 | matrix metallopeptidase 12 | -0.0333136 |
| FN1 | fibronectin 1 | -0.0331628 |
| TUBB | tubulin, beta class I | -0.0330467 |
| SEC24A | SEC24 family member A | -0.032962 |
| CUX1 | cut-like homeobox 1 | -0.0325466 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0325082 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0324864 |
| INSIG1 | insulin induced gene 1 | -0.0320955 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0313831 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0309928 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0305019 |
| SEPTIN9 | septin 9 | -0.0303871 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0303593 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.02879 |
| TMSB10 | thymosin beta 10 | -0.0287842 |
| SRPK2 | SRSF protein kinase 2 | -0.0282652 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0273784 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0271327 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0266791 |
| LAMA5 | laminin, alpha 5 | -0.0265327 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.026369 |
| TAOK1 | TAO kinase 1 | -0.0259753 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0258149 |
| GLG1 | golgi glycoprotein 1 | -0.0258065 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0257876 |
| CERT1 | ceramide transporter 1 | -0.0253975 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0251176 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0250961 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247439 |
| LMNA | lamin A/C | -0.0246842 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0245135 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0244554 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0241175 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0239325 |
| PFKP | phosphofructokinase, platelet | -0.023925 |
| CAVIN1 | caveolae associated protein 1 | -0.0238256 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0238178 |
| S100A10 | S100 calcium binding protein A10 | -0.0238032 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0237814 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0233163 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0231033 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0230989 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.02307 |
