| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.111801 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.10773 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.086602 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0826083 |
| AREG | amphiregulin | 0.0652998 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0639186 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0510251 |
| FTL | ferritin, light polypeptide | 0.0509496 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0478985 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0475999 |
| PCBP2 | poly(rC) binding protein 2 | 0.0467557 |
| TMSB10 | thymosin beta 10 | 0.0461849 |
| MKI67 | marker of proliferation Ki-67 | 0.0458027 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0452279 |
| RPS3 | ribosomal protein S3 | 0.0444761 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0434241 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0426477 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0399422 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0392605 |
| RPL12 | ribosomal protein L12 | 0.0383509 |
| PDGFC | platelet derived growth factor C | 0.0383235 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0381596 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0377933 |
| ANXA1 | annexin A1 | 0.0377518 |
| RPL23 | ribosomal protein L23 | 0.0370965 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0359435 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0358778 |
| RPS12 | ribosomal protein S12 | 0.0357562 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0346007 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340105 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033456 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033416 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0330876 |
| RPL3 | ribosomal protein L3 | 0.0329835 |
| CCNL1 | cyclin L1 | 0.0328628 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0327441 |
| PCM1 | pericentriolar material 1 | 0.0321442 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0320318 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0316176 |
| RPS8 | ribosomal protein S8 | 0.0311332 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0311135 |
| YBX3 | Y box binding protein 3 | 0.0306831 |
| RRM2 | ribonucleotide reductase M2 | 0.0305765 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0304107 |
| BRD2 | bromodomain containing 2 | 0.030177 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0298363 |
| RTN4 | reticulon 4 | 0.0294757 |
| IPO7 | importin 7 | 0.0294217 |
| RPS6 | ribosomal protein S6 | 0.0288918 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0288372 |
| JMJD1C | jumonji domain containing 1C | 0.0274217 |
| TPI1 | triosephosphate isomerase 1 | 0.0272452 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271714 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.027063 |
| RPS19 | ribosomal protein S19 | 0.0268993 |
| RPS2 | ribosomal protein S2 | 0.0265004 |
| KIF5B | kinesin family member 5B | 0.0264318 |
| KLF6 | Kruppel-like factor 6 | 0.0259611 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0258468 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.025842 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0255582 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.025292 |
| RPS27A | ribosomal protein S27a | 0.0252262 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0251915 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.025059 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0250189 |
| XPOT | exportin, tRNA | 0.0247626 |
| TXNRD1 | thioredoxin reductase 1 | 0.0247361 |
| RPL26 | ribosomal protein L26 | 0.0246723 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0246498 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245122 |
| PRKCI | protein kinase C, iota | 0.0242604 |
| RACK1 | receptor for activated C kinase 1 | 0.0240599 |
| TMEM41B | transmembrane protein 41B | 0.0237319 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0236085 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0236071 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0235963 |
| RPS7 | ribosomal protein S7 | 0.0232861 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0231256 |
| ATP11A | ATPase, class VI, type 11A | 0.0230025 |
| CCDC200 | coiled-coil domain containing 200 | 0.0228906 |
| EZR | ezrin | 0.0228848 |
| SFTPA2 | surfactant protein A2 | 0.0227524 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.022533 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0224861 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0223406 |
| CEP192 | centrosomal protein 192kDa | 0.0223206 |
| ENO1 | enolase 1, (alpha) | 0.0221246 |
| RPLP2 | ribosomal protein, large, P2 | 0.0221091 |
| AXIN2 | axin 2 | 0.0220066 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0219503 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.021564 |
| YBX1 | Y box binding protein 1 | 0.021433 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0213709 |
| USP47 | ubiquitin specific peptidase 47 | 0.0210985 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0209671 |
| ZNF638 | zinc finger protein 638 | 0.0208136 |
| ITSN2 | intersectin 2 | 0.020534 |
| TPR | translocated promoter region, nuclear basket protein | 0.0203522 |
| YTHDC1 | YTH domain containing 1 | 0.0203251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.306761 |
| NLGN1 | neuroligin 1 | -0.258436 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.185153 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.11734 |
| ACTG1 | actin gamma 1 | -0.10718 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0769694 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0692013 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0656887 |
| NHSL1 | NHS-like 1 | -0.0646592 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0618157 |
| MMP12 | matrix metallopeptidase 12 | -0.0616096 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0592445 |
| HMGA1 | high mobility group AT-hook 1 | -0.0591872 |
| PCDH7 | protocadherin 7 | -0.0576047 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0562978 |
| POTEF | POTE ankyrin domain family, member F | -0.0557891 |
| EHBP1 | EH domain binding protein 1 | -0.0555543 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0540975 |
| TMEM123 | transmembrane protein 123 | -0.0529345 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0524301 |
| TUBA1B | tubulin, alpha 1b | -0.0519855 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0506502 |
| EGR1 | early growth response 1 | -0.0495073 |
| TENM3 | teneurin transmembrane protein 3 | -0.0484763 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0482303 |
| BCHE | butyrylcholinesterase | -0.0480051 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0472024 |
| ZNF804A | zinc finger protein 804A | -0.0446759 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043949 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0435004 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0419455 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0407655 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0407436 |
| RASAL2 | RAS protein activator like 2 | -0.0404579 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0399928 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0372778 |
| TUBB | tubulin, beta class I | -0.0370857 |
| CLDN1 | claudin 1 | -0.0364939 |
| MGAT4C | MGAT4 family, member C | -0.0355677 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0352244 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0347626 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0340966 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0334499 |
| SYT1 | synaptotagmin I | -0.0328387 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.032384 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0317191 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0314942 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.031421 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0312971 |
| DST | dystonin | -0.0311603 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0303184 |
| NF1 | neurofibromin 1 | -0.0297153 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0295915 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0293829 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0292776 |
| KSR2 | kinase suppressor of ras 2 | -0.0292133 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0291262 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0291128 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0287428 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0282091 |
| ZNF207 | zinc finger protein 207 | -0.0278048 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.027356 |
| NABP1 | nucleic acid binding protein 1 | -0.0272609 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0266902 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0261438 |
| EXOC4 | exocyst complex component 4 | -0.0255036 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.025369 |
| TUBA1C | tubulin, alpha 1c | -0.0253168 |
| CCN2 | cellular communication network factor 2 | -0.025092 |
| TMEM108 | transmembrane protein 108 | -0.024948 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0244779 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0242858 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0242672 |
| TGM2 | transglutaminase 2 | -0.0239424 |
| TAPBP | TAP binding protein (tapasin) | -0.0239156 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0238268 |
| DIAPH2 | diaphanous-related formin 2 | -0.023767 |
| DTNA | dystrobrevin, alpha | -0.0234496 |
| CUX1 | cut-like homeobox 1 | -0.0233549 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.023333 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0232063 |
| FSTL5 | follistatin-like 5 | -0.0228951 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0227644 |
| CCND1 | cyclin D1 | -0.0225549 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0225278 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0222592 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0220475 |
| FASN | fatty acid synthase | -0.0218444 |
| GPHN | gephyrin | -0.0217995 |
| LDHB | lactate dehydrogenase B | -0.021388 |
| SRPK2 | SRSF protein kinase 2 | -0.0213576 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0213012 |
| AK1 | adenylate kinase 1 | -0.0212252 |
| PRR16 | proline rich 16 | -0.0211684 |
| HMGA2 | high mobility group AT-hook 2 | -0.0210702 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0210235 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.020943 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0208119 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0207419 |
| RANBP17 | RAN binding protein 17 | -0.0204867 |
