| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine (maleate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.118285 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0774906 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0766045 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0747009 |
| NAV2 | neuron navigator 2 | 0.072726 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0674714 |
| B2M | beta-2-microglobulin | 0.0671023 |
| SFTPA2 | surfactant protein A2 | 0.060599 |
| INTS6 | integrator complex subunit 6 | 0.058437 |
| IFI44L | interferon-induced protein 44-like | 0.0582064 |
| CTBP2 | C-terminal binding protein 2 | 0.0541708 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0536844 |
| MSN | moesin | 0.0526968 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0523278 |
| KYNU | kynureninase | 0.0521258 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0500554 |
| VEGFA | vascular endothelial growth factor A | 0.0486945 |
| PAX8 | paired box 8 | 0.0461046 |
| NDRG1 | N-myc downstream regulated 1 | 0.0451684 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0447348 |
| TPM3 | tropomyosin 3 | 0.0432534 |
| RNF213 | ring finger protein 213 | 0.0431952 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0423929 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0418611 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0416721 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.041652 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0401696 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0400888 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0396785 |
| PCBP2 | poly(rC) binding protein 2 | 0.039385 |
| HDAC9 | histone deacetylase 9 | 0.037979 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0370367 |
| MT2A | metallothionein 2A | 0.0355688 |
| FRMD4A | FERM domain containing 4A | 0.0355154 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0354965 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347987 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0347611 |
| SON | SON DNA binding protein | 0.034693 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0346591 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344319 |
| MX1 | MX dynamin-like GTPase 1 | 0.0336645 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0332891 |
| LYST | lysosomal trafficking regulator | 0.0331513 |
| FMNL2 | formin-like 2 | 0.0329733 |
| EGFR | epidermal growth factor receptor | 0.0317185 |
| TLE4 | transducin-like enhancer of split 4 | 0.0300343 |
| TLN1 | talin 1 | 0.0296608 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0293717 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0292825 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0292722 |
| TUT7 | terminal uridylyl transferase 7 | 0.0290458 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0286933 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0285747 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.027993 |
| GOLGB1 | golgin B1 | 0.0275593 |
| RPS17 | ribosomal protein S17 | 0.0270224 |
| GPC5 | glypican 5 | 0.0268521 |
| PLEC | plectin | 0.026745 |
| USP47 | ubiquitin specific peptidase 47 | 0.0265864 |
| SP100 | SP100 nuclear antigen | 0.0263887 |
| RPL3 | ribosomal protein L3 | 0.026361 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0263447 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0263169 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0262578 |
| UBAP2 | ubiquitin associated protein 2 | 0.0253383 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0253293 |
| FTL | ferritin, light polypeptide | 0.0252169 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0251273 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0250034 |
| BRD4 | bromodomain containing 4 | 0.0248573 |
| ATF4 | activating transcription factor 4 | 0.0246958 |
| MYOF | myoferlin | 0.0245562 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0243848 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0243741 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0237959 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0237895 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0235997 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0235649 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0235365 |
| HDGF | hepatoma-derived growth factor | 0.0235148 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0231079 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.023068 |
| COG6 | component of oligomeric golgi complex 6 | 0.023005 |
| NUP98 | nucleoporin 98kDa | 0.0228903 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0228675 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226934 |
| TGM2 | transglutaminase 2 | 0.0224868 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0224403 |
| MCL1 | myeloid cell leukemia 1 | 0.0222139 |
| SEPTIN9 | septin 9 | 0.0221898 |
| RPS19 | ribosomal protein S19 | 0.0221894 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0221714 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0221425 |
| ZNF638 | zinc finger protein 638 | 0.0219759 |
| CHMP5 | charged multivesicular body protein 5 | 0.0218119 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0216111 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0215553 |
| MNT | MAX network transcriptional repressor | 0.0213916 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0213547 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0209603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.183079 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165372 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140396 |
| ASPH | aspartate beta-hydroxylase | -0.119229 |
| VIM | vimentin | -0.111308 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109012 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0774955 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0774211 |
| CP | ceruloplasmin (ferroxidase) | -0.0743007 |
| RAI14 | retinoic acid induced 14 | -0.0728352 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0719564 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0639644 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0614474 |
| STK17A | serine/threonine kinase 17a | -0.0612219 |
| CAVIN1 | caveolae associated protein 1 | -0.0592769 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0575058 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0572118 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0565296 |
| SDCBP | syndecan binding protein (syntenin) | -0.0547924 |
| GLIS3 | GLIS family zinc finger 3 | -0.0543813 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0512745 |
| TPM4 | tropomyosin 4 | -0.0511358 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0503922 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0503723 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0500566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0500375 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0493714 |
| GPC6 | glypican 6 | -0.0492398 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0486036 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0478394 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0469395 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.046698 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0464016 |
| ANXA2 | annexin A2 | -0.0449174 |
| RHEB | Ras homolog enriched in brain | -0.0445042 |
| RPS24 | ribosomal protein S24 | -0.0444886 |
| GNAS | GNAS complex locus | -0.0443682 |
| TMEM263 | transmembrane protein 263 | -0.0443651 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0442004 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0440586 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0430819 |
| ARF1 | ADP-ribosylation factor 1 | -0.0429778 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0422459 |
| ACTG1 | actin gamma 1 | -0.0415204 |
| PTMA | prothymosin, alpha | -0.040439 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0401904 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0400038 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0399736 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0397207 |
| POTEF | POTE ankyrin domain family, member F | -0.0395703 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0385069 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0383142 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0376594 |
| HLA-B | major histocompatibility complex, class I, B | -0.0366804 |
| G0S2 | G0/G1 switch 2 | -0.036623 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0357606 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0357371 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0356701 |
| CD70 | CD70 molecule | -0.0355674 |
| RTN4 | reticulon 4 | -0.0352827 |
| MAP1B | microtubule-associated protein 1B | -0.0347201 |
| SP3 | Sp3 transcription factor | -0.034638 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0341451 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0340976 |
| TMEM123 | transmembrane protein 123 | -0.0337488 |
| ANXA4 | annexin A4 | -0.0335979 |
| DENND2B | DENN domain containing 2B | -0.0335646 |
| TRAM1 | translocation associated membrane protein 1 | -0.0332847 |
| FN1 | fibronectin 1 | -0.0330454 |
| CA12 | carbonic anhydrase XII | -0.0328835 |
| UBC | ubiquitin C | -0.0326635 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0326235 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0324986 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0321401 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0318348 |
| NRP1 | neuropilin 1 | -0.0312495 |
| TNS3 | tensin 3 | -0.0310616 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0310482 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0309664 |
| PXDN | peroxidasin | -0.0309513 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0307453 |
| FAT1 | FAT atypical cadherin 1 | -0.0307424 |
| GDF15 | growth differentiation factor 15 | -0.0305361 |
| VCL | vinculin | -0.0305191 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0304674 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0304268 |
| CALU | calumenin | -0.0303389 |
| PTGR1 | prostaglandin reductase 1 | -0.0300463 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.029954 |
| TRIM56 | tripartite motif containing 56 | -0.0297126 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0292818 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0291997 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0290927 |
| GLG1 | golgi glycoprotein 1 | -0.0290633 |
| RPLP0 | ribosomal protein, large, P0 | -0.0290278 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0290258 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0290224 |
| RPL34 | ribosomal protein L34 | -0.0285091 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0284479 |
| TPM1 | tropomyosin 1 (alpha) | -0.0282082 |
