| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.170523 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.135627 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0796195 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0790195 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0625883 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0616599 |
| STC1 | stanniocalcin 1 | 0.0572753 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0524289 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0519584 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0516364 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0506025 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0504002 |
| RPS2 | ribosomal protein S2 | 0.0503427 |
| RPS3 | ribosomal protein S3 | 0.0491738 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0491181 |
| RPS12 | ribosomal protein S12 | 0.0487098 |
| INTS6 | integrator complex subunit 6 | 0.0478418 |
| RPL37A | ribosomal protein L37a | 0.0472607 |
| MCL1 | myeloid cell leukemia 1 | 0.0472318 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0463854 |
| RPS17 | ribosomal protein S17 | 0.0397531 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0390679 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.037022 |
| RPS27A | ribosomal protein S27a | 0.0358281 |
| RPL26 | ribosomal protein L26 | 0.035775 |
| DUSP16 | dual specificity phosphatase 16 | 0.0333214 |
| BMP6 | bone morphogenetic protein 6 | 0.0333043 |
| FLNA | filamin A, alpha | 0.032806 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0319459 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0318975 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0313858 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0313725 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0310457 |
| EGFR | epidermal growth factor receptor | 0.0307747 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0307598 |
| RPL35A | ribosomal protein L35a | 0.0306742 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0305498 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0301101 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0300359 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0299875 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0299342 |
| FRMD6 | FERM domain containing 6 | 0.0296215 |
| FAT1 | FAT atypical cadherin 1 | 0.0294986 |
| FMNL2 | formin-like 2 | 0.0294217 |
| TNS1 | tensin 1 | 0.0292257 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0286133 |
| RPL31 | ribosomal protein L31 | 0.0285586 |
| ATF4 | activating transcription factor 4 | 0.0284877 |
| AADAC | arylacetamide deacetylase | 0.0284823 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0280653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0278513 |
| CTBP2 | C-terminal binding protein 2 | 0.0274573 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0271141 |
| GOLGB1 | golgin B1 | 0.0264344 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0260856 |
| RPL11 | ribosomal protein L11 | 0.0259078 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0258216 |
| RPS8 | ribosomal protein S8 | 0.025746 |
| ETNK1 | ethanolamine kinase 1 | 0.0256919 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256696 |
| MSN | moesin | 0.0252975 |
| PLEC | plectin | 0.0250789 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025068 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0249728 |
| TCIM | transcriptional and immune response regulator | 0.0248532 |
| SP100 | SP100 nuclear antigen | 0.0243438 |
| RPS7 | ribosomal protein S7 | 0.0243231 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0240554 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0240065 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235784 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0235739 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0232457 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0231552 |
| DUSP5 | dual specificity phosphatase 5 | 0.0229733 |
| ZFP36 | ZFP36 ring finger protein | 0.0228286 |
| BRD2 | bromodomain containing 2 | 0.0224926 |
| ZNF638 | zinc finger protein 638 | 0.0221976 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0221491 |
| RACK1 | receptor for activated C kinase 1 | 0.0217241 |
| RHCG | Rh family, C glycoprotein | 0.0216971 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0216941 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0215552 |
| ACTN1 | actinin, alpha 1 | 0.0213985 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0212327 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0210695 |
| RPS14 | ribosomal protein S14 | 0.0208845 |
| LMO7 | LIM domain 7 | 0.0205679 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0205265 |
| PRKCE | protein kinase C, epsilon | 0.0203455 |
| RPL9 | ribosomal protein L9 | 0.019991 |
| LAMC2 | laminin, gamma 2 | 0.019938 |
| USP47 | ubiquitin specific peptidase 47 | 0.019834 |
| WWOX | WW domain containing oxidoreductase | 0.0197115 |
| SMAD3 | SMAD family member 3 | 0.0196753 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0194828 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0194728 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0194706 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0192551 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0191354 |
| HMGA2 | high mobility group AT-hook 2 | 0.0185966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.257789 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.180085 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.142258 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.107686 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.103871 |
| TXNRD1 | thioredoxin reductase 1 | -0.0987417 |
| USP3 | ubiquitin specific peptidase 3 | -0.0942616 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0870403 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0840055 |
| CA12 | carbonic anhydrase XII | -0.0767868 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0765344 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0754207 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0749655 |
| FTL | ferritin, light polypeptide | -0.0724449 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0717626 |
| KRT81 | keratin 81, type II | -0.0656161 |
| EHBP1 | EH domain binding protein 1 | -0.0648794 |
| SBF2 | SET binding factor 2 | -0.0637495 |
| EFNA5 | ephrin-A5 | -0.0636911 |
| ACTG1 | actin gamma 1 | -0.0633677 |
| PGK1 | phosphoglycerate kinase 1 | -0.063075 |
| MT1X | metallothionein 1X | -0.0573672 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0554988 |
| MAP1B | microtubule-associated protein 1B | -0.0554835 |
| TMSB10 | thymosin beta 10 | -0.0531388 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0528666 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0525786 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0512442 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.050875 |
| TNS3 | tensin 3 | -0.0487432 |
| TKT | transketolase | -0.0484458 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0482847 |
| S100A10 | S100 calcium binding protein A10 | -0.0480096 |
| UBC | ubiquitin C | -0.0479614 |
| RIN2 | Ras and Rab interactor 2 | -0.0472863 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0467997 |
| HELZ | helicase with zinc finger | -0.0461209 |
| RTN4 | reticulon 4 | -0.044211 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.044168 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0438685 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0436278 |
| ANXA2 | annexin A2 | -0.0434931 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.043353 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0430066 |
| OSMR | oncostatin M receptor | -0.0429858 |
| DENND4C | DENN/MADD domain containing 4C | -0.0429714 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.04255 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0414111 |
| NRP1 | neuropilin 1 | -0.0413555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0408807 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0401631 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0396765 |
| SPAG9 | sperm associated antigen 9 | -0.0387384 |
| NCOR1 | nuclear receptor corepressor 1 | -0.038355 |
| PKM | pyruvate kinase, muscle | -0.0364675 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0364367 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0360773 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0355523 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0352618 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0350576 |
| RNF213 | ring finger protein 213 | -0.034912 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0346842 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034305 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0342387 |
| S100A6 | S100 calcium binding protein A6 | -0.0338943 |
| ASPH | aspartate beta-hydroxylase | -0.0335841 |
| RAI14 | retinoic acid induced 14 | -0.0335683 |
| PTK2 | protein tyrosine kinase 2 | -0.0334654 |
| ANLN | anillin, actin binding protein | -0.0332067 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0329422 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0329013 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0321982 |
| NDRG1 | N-myc downstream regulated 1 | -0.0321497 |
| TMEM123 | transmembrane protein 123 | -0.031897 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.031651 |
| POTEF | POTE ankyrin domain family, member F | -0.0315792 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0315107 |
| TPM4 | tropomyosin 4 | -0.0314849 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.031326 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0312684 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0312585 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0312456 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0312327 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0310121 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0309209 |
| WDR45B | WD repeat domain 45B | -0.0308094 |
| CD99 | CD99 molecule | -0.0306007 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304409 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0304309 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303378 |
| OLA1 | Obg-like ATPase 1 | -0.0302896 |
| TPM1 | tropomyosin 1 (alpha) | -0.0302256 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0301732 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.030099 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0298088 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0297315 |
| ZNF292 | zinc finger protein 292 | -0.0297169 |
| RPL32 | ribosomal protein L32 | -0.028698 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0286709 |
| AOPEP | aminopeptidase O (putative) | -0.0282951 |
