| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117732 |
| VEGFA | vascular endothelial growth factor A | 0.0929329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0890933 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0749428 |
| RPS2 | ribosomal protein S2 | 0.063454 |
| TMSB4X | thymosin beta 4, X-linked | 0.0617514 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0606472 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0605591 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0531442 |
| BCOR | BCL6 corepressor | 0.0506547 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0471456 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0453367 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0451503 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0446324 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0424463 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0389328 |
| RPL3 | ribosomal protein L3 | 0.037347 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0368764 |
| RPS12 | ribosomal protein S12 | 0.0343021 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0332221 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331301 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0327049 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0323456 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0322138 |
| PDE10A | phosphodiesterase 10A | 0.0316098 |
| SET | SET nuclear proto-oncogene | 0.0315534 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0315449 |
| MYOF | myoferlin | 0.0307834 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0290299 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0284738 |
| ANO6 | anoctamin 6 | 0.0273814 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0270777 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0270462 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0269554 |
| RPS3 | ribosomal protein S3 | 0.0268914 |
| RAD51B | RAD51 paralog B | 0.0268495 |
| ZNF608 | zinc finger protein 608 | 0.0263036 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262947 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0260919 |
| BRD2 | bromodomain containing 2 | 0.0256921 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0255467 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0251923 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0251249 |
| RPS18 | ribosomal protein S18 | 0.0250008 |
| SFTPA2 | surfactant protein A2 | 0.0249287 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0245605 |
| AATF | apoptosis antagonizing transcription factor | 0.0242177 |
| EGFR | epidermal growth factor receptor | 0.0239769 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0233617 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0230715 |
| VIM | vimentin | 0.0228218 |
| TPM3 | tropomyosin 3 | 0.0224855 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0222031 |
| RACK1 | receptor for activated C kinase 1 | 0.0221448 |
| IGF2 | insulin-like growth factor 2 | 0.0219406 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0218679 |
| CNN3 | calponin 3, acidic | 0.0212961 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0212799 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0212221 |
| ADM | adrenomedullin | 0.0212062 |
| RPL26 | ribosomal protein L26 | 0.0210641 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.02083 |
| FRMD6 | FERM domain containing 6 | 0.0205853 |
| ATF4 | activating transcription factor 4 | 0.0204808 |
| RPS3A | ribosomal protein S3A | 0.020395 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0202754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0202311 |
| RPS7 | ribosomal protein S7 | 0.020167 |
| SLK | STE20-like kinase | 0.0201617 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0199502 |
| TLN1 | talin 1 | 0.0199304 |
| ZNF146 | zinc finger protein 146 | 0.0193183 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0191569 |
| H4C15 | H4 clustered histone 15 | 0.0190885 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0187515 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0185855 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0185685 |
| SIK3 | SIK family kinase 3 | 0.0184937 |
| YBX1 | Y box binding protein 1 | 0.018445 |
| MED13L | mediator complex subunit 13-like | 0.018417 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0181419 |
| EZR | ezrin | 0.0180701 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0179992 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0178439 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0177727 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0174655 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0173168 |
| BCORL1 | BCL6 corepressor-like 1 | 0.0172108 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0171506 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0171027 |
| AOPEP | aminopeptidase O (putative) | 0.0170863 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0169429 |
| DENR | density-regulated protein | 0.0169296 |
| MATR3 | matrin 3 | 0.0168203 |
| HOXA3 | homeobox A3 | 0.0166391 |
| H1-4 | H1.4 linker histone, cluster member | 0.0165477 |
| ATP11A | ATPase, class VI, type 11A | 0.0164316 |
| SDF4 | stromal cell derived factor 4 | 0.016321 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0161471 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.016065 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.265768 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.128436 |
| PEG10 | paternally expressed 10 | -0.120395 |
| MGP | matrix Gla protein | -0.101935 |
| ACTG1 | actin gamma 1 | -0.082378 |
| CENPF | centromere protein F, 350/400kDa | -0.0756561 |
| RPS24 | ribosomal protein S24 | -0.0712205 |
| CADM2 | cell adhesion molecule 2 | -0.067393 |
| IER3 | immediate early response 3 | -0.06653 |
| TUBB | tubulin, beta class I | -0.0652525 |
| RPLP0 | ribosomal protein, large, P0 | -0.0634831 |
| PTMA | prothymosin, alpha | -0.0633174 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0610706 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0579687 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0568246 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0560542 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0558072 |
| MEOX2 | mesenchyme homeobox 2 | -0.0532637 |
| CENPE | centromere protein E, 312kDa | -0.0530717 |
| DEK | DEK proto-oncogene | -0.0530343 |
| SBF2 | SET binding factor 2 | -0.0497105 |
| NFIB | nuclear factor I/B | -0.0489586 |
| RPL34 | ribosomal protein L34 | -0.0454098 |
| RPS6 | ribosomal protein S6 | -0.0443228 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0434991 |
| RPS11 | ribosomal protein S11 | -0.0425064 |
| RPS23 | ribosomal protein S23 | -0.0418729 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.041139 |
| COL1A2 | collagen, type I, alpha 2 | -0.0403134 |
| MKI67 | marker of proliferation Ki-67 | -0.0402196 |
| RPS19 | ribosomal protein S19 | -0.0394626 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0392659 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0390588 |
| TMSB10 | thymosin beta 10 | -0.0390127 |
| PTK2 | protein tyrosine kinase 2 | -0.0387299 |
| SRPK2 | SRSF protein kinase 2 | -0.0384452 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.038324 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0381037 |
| HMGA2 | high mobility group AT-hook 2 | -0.0377681 |
| RPLP1 | ribosomal protein, large, P1 | -0.0372857 |
| FOXC1 | forkhead box C1 | -0.0370991 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.036037 |
| CCNI | cyclin I | -0.0354179 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.035187 |
| TUBA1B | tubulin, alpha 1b | -0.0351852 |
| TPX2 | TPX2, microtubule-associated | -0.0349705 |
| RPS25 | ribosomal protein S25 | -0.0348867 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0335931 |
| RPS10 | ribosomal protein S10 | -0.0329813 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324197 |
| RPL27A | ribosomal protein L27a | -0.0322137 |
| RPS13 | ribosomal protein S13 | -0.0321655 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0317318 |
| TPM4 | tropomyosin 4 | -0.0312141 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0304599 |
| WASF2 | WAS protein family, member 2 | -0.0302599 |
| NFIA | nuclear factor I/A | -0.0302004 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0300524 |
| FBXO11 | F-box protein 11 | -0.030003 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0297574 |
| RPL8 | ribosomal protein L8 | -0.0294464 |
| S100A9 | S100 calcium binding protein A9 | -0.0292196 |
| RANBP17 | RAN binding protein 17 | -0.0291746 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0283605 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0283192 |
| FTL | ferritin, light polypeptide | -0.0283018 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0278715 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0277014 |
| KLHL24 | kelch-like family member 24 | -0.0274354 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.0272815 |
| AK1 | adenylate kinase 1 | -0.0272416 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.027174 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0270187 |
| RPS15 | ribosomal protein S15 | -0.0268414 |
| ECT2 | epithelial cell transforming 2 | -0.0267127 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0266832 |
| USP3 | ubiquitin specific peptidase 3 | -0.0266222 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0265863 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.026241 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0260069 |
| RPS21 | ribosomal protein S21 | -0.0259759 |
| RPL35A | ribosomal protein L35a | -0.0258923 |
| HDLBP | high density lipoprotein binding protein | -0.0258593 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0256692 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0256334 |
| NEK7 | NIMA-related kinase 7 | -0.0252494 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0251674 |
| R3HDM1 | R3H domain containing 1 | -0.0250376 |
| KIF13A | kinesin family member 13A | -0.0250219 |
| RPL32 | ribosomal protein L32 | -0.0248787 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0248479 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0248105 |
| RPL28 | ribosomal protein L28 | -0.0246812 |
| GNAS | GNAS complex locus | -0.0246152 |
| TUT4 | terminal uridylyl transferase 4 | -0.0245263 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0243765 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0243151 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0242249 |
| RPS5 | ribosomal protein S5 | -0.024129 |
| DIAPH3 | diaphanous-related formin 3 | -0.0241261 |
