| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.124975 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0993808 |
| EFNA5 | ephrin-A5 | 0.065517 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0583516 |
| FMNL2 | formin-like 2 | 0.052995 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0519119 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0509021 |
| FLNB | filamin B, beta | 0.0487267 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.045597 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0454383 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.045406 |
| BMP6 | bone morphogenetic protein 6 | 0.0447775 |
| TGM2 | transglutaminase 2 | 0.0429499 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0417751 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0389376 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0377262 |
| MSN | moesin | 0.0364297 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0360363 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0355058 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0346376 |
| TLN1 | talin 1 | 0.0339328 |
| EGFR | epidermal growth factor receptor | 0.0330316 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0321353 |
| PLEC | plectin | 0.0320205 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0311382 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0306233 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0305599 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0302752 |
| FLNA | filamin A, alpha | 0.0289654 |
| PMM2 | phosphomannomutase 2 | 0.0279465 |
| CD44 | CD44 molecule (Indian blood group) | 0.0275877 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0273081 |
| MT2A | metallothionein 2A | 0.0261263 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0254397 |
| DSPP | dentin sialophosphoprotein | 0.0252711 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0246405 |
| INTS6 | integrator complex subunit 6 | 0.0246392 |
| EFNB2 | ephrin-B2 | 0.0242958 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0229318 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.022795 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0227803 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0221737 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022084 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0215468 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0214929 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0214345 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0213615 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0213543 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0212374 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0205301 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0204208 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0199192 |
| MYO5B | myosin VB | 0.0197614 |
| TPM3 | tropomyosin 3 | 0.0195118 |
| MCL1 | myeloid cell leukemia 1 | 0.0193456 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0191713 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0189642 |
| HMGA2 | high mobility group AT-hook 2 | 0.018865 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0187982 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0178804 |
| ZNF638 | zinc finger protein 638 | 0.0174706 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0173946 |
| RAI14 | retinoic acid induced 14 | 0.017108 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0169474 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0168897 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0167672 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0167618 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0166754 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0164932 |
| ACTN1 | actinin, alpha 1 | 0.016453 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0163021 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0160349 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0159653 |
| KLC1 | kinesin light chain 1 | 0.0158702 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0156668 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0156347 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0155645 |
| GRAMD2B | GRAM domain containing 2B | 0.0155394 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0153965 |
| SON | SON DNA binding protein | 0.0153155 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0153141 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.015272 |
| RUNX1 | runt-related transcription factor 1 | 0.0150864 |
| VEGFA | vascular endothelial growth factor A | 0.0149419 |
| CAPRIN2 | caprin family member 2 | 0.0148652 |
| STRIP2 | striatin interacting protein 2 | 0.014863 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0148369 |
| LAMB3 | laminin, beta 3 | 0.0147918 |
| ATP13A3 | ATPase type 13A3 | 0.0147555 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0146504 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0139592 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0138767 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0138549 |
| CTBP2 | C-terminal binding protein 2 | 0.0137097 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.013587 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0134247 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0134105 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0133488 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0133457 |
| RASA3 | RAS p21 protein activator 3 | 0.0132859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.141401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141162 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.135066 |
| MUC17 | mucin 17, cell surface associated | -0.121937 |
| LMO7 | LIM domain 7 | -0.120867 |
| POTEF | POTE ankyrin domain family, member F | -0.116402 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.115175 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.11226 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.109343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105959 |
| HMGA1 | high mobility group AT-hook 1 | -0.103398 |
| PTMA | prothymosin, alpha | -0.0955712 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0898756 |
| TMSB10 | thymosin beta 10 | -0.0879534 |
| KLK10 | kallikrein-related peptidase 10 | -0.0851597 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0819329 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0801414 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0774193 |
| S100A10 | S100 calcium binding protein A10 | -0.076449 |
| VIM | vimentin | -0.0709752 |
| ACTG1 | actin gamma 1 | -0.0701884 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0699851 |
| DSG2 | desmoglein 2 | -0.0697871 |
| VCAN | versican | -0.0695717 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.069122 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.06737 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0646992 |
| PERP | PERP, TP53 apoptosis effector | -0.064555 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0628009 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0622193 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0620909 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0616222 |
| EMP1 | epithelial membrane protein 1 | -0.0593968 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0588755 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0585424 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0581225 |
| S100A4 | S100 calcium binding protein A4 | -0.0580787 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0577063 |
| SQSTM1 | sequestosome 1 | -0.0566255 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0550671 |
| VCL | vinculin | -0.0550069 |
| CD2AP | CD2-associated protein | -0.0549651 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0542848 |
| LAMA4 | laminin, alpha 4 | -0.0541291 |
| TXNRD1 | thioredoxin reductase 1 | -0.05378 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0533465 |
| UBC | ubiquitin C | -0.0524783 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0518797 |
| S100A6 | S100 calcium binding protein A6 | -0.0511972 |
| EGR1 | early growth response 1 | -0.0509032 |
| GNAS | GNAS complex locus | -0.0504616 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0501175 |
| WASF2 | WAS protein family, member 2 | -0.0485261 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0475037 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0471853 |
| EZR | ezrin | -0.0470719 |
| LDHA | lactate dehydrogenase A | -0.0470422 |
| SPAG9 | sperm associated antigen 9 | -0.0454856 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0453742 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0450201 |
| MYOF | myoferlin | -0.0449598 |
| RPL34 | ribosomal protein L34 | -0.0446505 |
| NPSR1 | neuropeptide S receptor 1 | -0.0441166 |
| KRT8 | keratin 8, type II | -0.0441022 |
| B2M | beta-2-microglobulin | -0.043458 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0434374 |
| FNDC3B | fibronectin type III domain containing 3B | -0.042852 |
| RTN4 | reticulon 4 | -0.0421252 |
| FOSL1 | FOS-like antigen 1 | -0.0418411 |
| PRSS3 | protease, serine, 3 | -0.0415855 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0414329 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0405278 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0404313 |
| RAD21 | RAD21 homolog (S. pombe) | -0.040314 |
| ACTN4 | actinin, alpha 4 | -0.0402876 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0397104 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0393058 |
| SLMAP | sarcolemma associated protein | -0.0390157 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0386233 |
| RIOK3 | RIO kinase 3 | -0.038475 |
| KRT18 | keratin 18, type I | -0.0383751 |
| ANXA2 | annexin A2 | -0.0371416 |
| ITGB4 | integrin, beta 4 | -0.0370648 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0368694 |
| CD59 | CD59 molecule, complement regulatory protein | -0.036716 |
| PGK1 | phosphoglycerate kinase 1 | -0.0364114 |
| JMJD1C | jumonji domain containing 1C | -0.0358605 |
| RPL8 | ribosomal protein L8 | -0.035548 |
| TPM4 | tropomyosin 4 | -0.0355138 |
| DIAPH2 | diaphanous-related formin 2 | -0.0352386 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0350252 |
| NEK7 | NIMA-related kinase 7 | -0.0349391 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0342855 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0342836 |
| ITGA6 | integrin, alpha 6 | -0.0341975 |
| KRT19 | keratin 19, type I | -0.033982 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0339681 |
| TMEM263 | transmembrane protein 263 | -0.0332779 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0332058 |
| SBF2 | SET binding factor 2 | -0.033203 |
