| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.130694 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0990625 |
| RPL23 | ribosomal protein L23 | 0.0554293 |
| DUSP16 | dual specificity phosphatase 16 | 0.052979 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0466151 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0449574 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0415909 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0403173 |
| VMP1 | vacuole membrane protein 1 | 0.0399935 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0376099 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0333221 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0319107 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0303282 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0296939 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0274596 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0264477 |
| SET | SET nuclear proto-oncogene | 0.0262376 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0261394 |
| MT2A | metallothionein 2A | 0.0260441 |
| FGB | fibrinogen beta chain | 0.025644 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0255806 |
| RPS3 | ribosomal protein S3 | 0.0253086 |
| NTN4 | netrin 4 | 0.0247727 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.023349 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0232919 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0232824 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0225775 |
| RPL12 | ribosomal protein L12 | 0.0225463 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0224184 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0210137 |
| SMAD3 | SMAD family member 3 | 0.0204725 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0204189 |
| STOM | stomatin | 0.0200185 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.019792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0197384 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0196501 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0194442 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0192597 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.019185 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0191591 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.018977 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0186924 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.018482 |
| RPS2 | ribosomal protein S2 | 0.0184296 |
| AREG | amphiregulin | 0.018114 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0180757 |
| B2M | beta-2-microglobulin | 0.017841 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0175251 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0175116 |
| ABHD17C | abhydrolase domain containing 17C | 0.0173704 |
| KLF6 | Kruppel-like factor 6 | 0.0172014 |
| SGMS1 | sphingomyelin synthase 1 | 0.017177 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0171731 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0171304 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0170689 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169189 |
| AHR | aryl hydrocarbon receptor | 0.016855 |
| VEGFA | vascular endothelial growth factor A | 0.0165183 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.015994 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0159421 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0157794 |
| EPAS1 | endothelial PAS domain protein 1 | 0.015697 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0156894 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.01568 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0156749 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0156513 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.015308 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0152532 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0145168 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0143859 |
| PRKD1 | protein kinase D1 | 0.01433 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0142789 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0141941 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0139334 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 | 0.0138879 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.013883 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0138659 |
| PLK2 | polo-like kinase 2 | 0.0137457 |
| INSR | insulin receptor | 0.0136351 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.013615 |
| HSPA8 | heat shock 70kDa protein 8 | 0.013469 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.013466 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0134652 |
| S100P | S100 calcium binding protein P | 0.0134389 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0133537 |
| RPS19 | ribosomal protein S19 | 0.0132794 |
| ADM | adrenomedullin | 0.0132579 |
| PNN | pinin, desmosome associated protein | 0.0130759 |
| IRS2 | insulin receptor substrate 2 | 0.0130045 |
| RACK1 | receptor for activated C kinase 1 | 0.0129666 |
| RPL26 | ribosomal protein L26 | 0.0129623 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0129071 |
| MED13L | mediator complex subunit 13-like | 0.012902 |
| DSPP | dentin sialophosphoprotein | 0.0128785 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0124868 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0123186 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.012227 |
| PDE10A | phosphodiesterase 10A | 0.0121695 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0120729 |
| RPS17 | ribosomal protein S17 | 0.0119102 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.228229 |
| ACACA | acetyl-CoA carboxylase alpha | -0.126341 |
| LASP1 | LIM and SH3 protein 1 | -0.105179 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0770311 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0710671 |
| CDK12 | cyclin-dependent kinase 12 | -0.0679582 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.067085 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0647112 |
| ACTG1 | actin gamma 1 | -0.0645801 |
| CLTC | clathrin, heavy chain (Hc) | -0.0642701 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0628634 |
| CEP250 | centrosomal protein 250kDa | -0.0625328 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0624479 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0622821 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0618308 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0597175 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0586917 |
| TMEM123 | transmembrane protein 123 | -0.0580793 |
| DTNA | dystrobrevin, alpha | -0.0563193 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0500874 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0496565 |
| DENND1A | DENN/MADD domain containing 1A | -0.0489406 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0481493 |
| PARD3 | par-3 family cell polarity regulator | -0.0481292 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0474066 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0465242 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0464069 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0457445 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0450542 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0440753 |
| NDRG1 | N-myc downstream regulated 1 | -0.0431957 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0414944 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0411844 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.040061 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0398782 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0388164 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0382163 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0379292 |
| VCP | valosin containing protein | -0.0366737 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0362712 |
| MMP24OS | MMP24 opposite strand | -0.0361166 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0359256 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.035827 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0357535 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0356621 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.035317 |
| PTK2 | protein tyrosine kinase 2 | -0.0348627 |
| SBF2 | SET binding factor 2 | -0.0341489 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0336851 |
| FASN | fatty acid synthase | -0.0333306 |
| EXOC4 | exocyst complex component 4 | -0.0330778 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0324001 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.032194 |
| KIF16B | kinesin family member 16B | -0.0319084 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0317969 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0316723 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0313701 |
| INTS6 | integrator complex subunit 6 | -0.0308099 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0306602 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305174 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0304814 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0297892 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0295866 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0294587 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0293182 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0292161 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0289528 |
| PKM | pyruvate kinase, muscle | -0.0286462 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0283427 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0282168 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0281683 |
| PRELID2 | PRELI domain containing 2 | -0.0270835 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0266895 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0266591 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.026412 |
| LDHA | lactate dehydrogenase A | -0.0260923 |
| ARF1 | ADP-ribosylation factor 1 | -0.0259022 |
| MSI2 | musashi RNA-binding protein 2 | -0.0253241 |
| JMJD1C | jumonji domain containing 1C | -0.02532 |
| FADS2 | fatty acid desaturase 2 | -0.0252995 |
| SMYD3 | SET and MYND domain containing 3 | -0.0252971 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.025288 |
| PRKCA | protein kinase C, alpha | -0.025234 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0251834 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0250337 |
| MAP4 | microtubule-associated protein 4 | -0.0248727 |
| SRPK2 | SRSF protein kinase 2 | -0.0246439 |
| RAB7A | RAB7A, member RAS oncogene family | -0.024588 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0242747 |
| KRT19 | keratin 19, type I | -0.0240953 |
| ASPH | aspartate beta-hydroxylase | -0.0239037 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0238072 |
| KRT8 | keratin 8, type II | -0.0235302 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0232973 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0231754 |
| RAD51B | RAD51 paralog B | -0.0230766 |
| CUX1 | cut-like homeobox 1 | -0.0227823 |
| POTEF | POTE ankyrin domain family, member F | -0.0227594 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0226784 |
| ZNF124 | zinc finger protein 124 | -0.0226395 |
