| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.240195 |
| COL5A2 | collagen, type V, alpha 2 | 0.185953 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0941908 |
| ZNF608 | zinc finger protein 608 | 0.0897512 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0890536 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0829877 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0748377 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0740927 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0724709 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0690899 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0577632 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0569254 |
| MKI67 | marker of proliferation Ki-67 | 0.0539598 |
| JMJD1C | jumonji domain containing 1C | 0.0508286 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0503366 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0503008 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.05025 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0442826 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0439376 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0437823 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0436401 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0435575 |
| RPS4X | ribosomal protein S4, X-linked | 0.0424508 |
| KIF5B | kinesin family member 5B | 0.0424495 |
| DST | dystonin | 0.0422537 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0419959 |
| OGA | O-GlcNAcase | 0.0407366 |
| TOX | thymocyte selection-associated high mobility group box | 0.0404618 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0404243 |
| RPS3 | ribosomal protein S3 | 0.0398713 |
| CENPF | centromere protein F, 350/400kDa | 0.0398101 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0395627 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0394038 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0391622 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0379324 |
| XPO1 | exportin 1 | 0.0377044 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0369828 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0364995 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0364593 |
| PCBP2 | poly(rC) binding protein 2 | 0.0364316 |
| TPR | translocated promoter region, nuclear basket protein | 0.036409 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0363496 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.036174 |
| RPS2 | ribosomal protein S2 | 0.0358915 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0357623 |
| PTMA | prothymosin, alpha | 0.035758 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0354237 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0348257 |
| RPS12 | ribosomal protein S12 | 0.0347278 |
| YBX1 | Y box binding protein 1 | 0.0346189 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0341999 |
| CCDC88A | coiled-coil domain containing 88A | 0.0340883 |
| TPI1 | triosephosphate isomerase 1 | 0.0338385 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0336517 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0334626 |
| ZNF638 | zinc finger protein 638 | 0.0333968 |
| ZNF292 | zinc finger protein 292 | 0.0331211 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0324823 |
| ADAR | adenosine deaminase, RNA-specific | 0.0322787 |
| PNN | pinin, desmosome associated protein | 0.0317839 |
| VCL | vinculin | 0.0316273 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0316106 |
| WLS | wntless Wnt ligand secretion mediator | 0.0311775 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0309557 |
| RPL12 | ribosomal protein L12 | 0.0309526 |
| BNC2 | basonuclin 2 | 0.0302913 |
| MATR3 | matrin 3 | 0.0292615 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0292446 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0292368 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0290842 |
| SON | SON DNA binding protein | 0.0290782 |
| NFIA | nuclear factor I/A | 0.0289619 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0285688 |
| HOMER1 | homer scaffolding protein 1 | 0.0285315 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0284584 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0282666 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0281238 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0277709 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0276997 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0275772 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0273153 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0272973 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0269831 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267358 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0266623 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0266555 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0266077 |
| SHROOM3 | shroom family member 3 | 0.0265456 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.026473 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0264265 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0263314 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0262273 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0261971 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0261056 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0260402 |
| RACK1 | receptor for activated C kinase 1 | 0.0258658 |
| ENO1 | enolase 1, (alpha) | 0.0258261 |
| FAM162A | family with sequence similarity 162, member A | 0.0257071 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.025321 |
| PGK1 | phosphoglycerate kinase 1 | 0.0253088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.269015 |
| ACTG1 | actin gamma 1 | -0.111291 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.104646 |
| NPAS3 | neuronal PAS domain protein 3 | -0.097205 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0897798 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0843447 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0817467 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0792433 |
| TENM3 | teneurin transmembrane protein 3 | -0.0759566 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0636999 |
| RPS11 | ribosomal protein S11 | -0.0505043 |
| RCC1 | regulator of chromosome condensation 1 | -0.0503895 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.047399 |
| RPS25 | ribosomal protein S25 | -0.046489 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0435841 |
| RAD51B | RAD51 paralog B | -0.0433904 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0432691 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0420736 |
| RPL31 | ribosomal protein L31 | -0.0416139 |
| RPS29 | ribosomal protein S29 | -0.0407304 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.040699 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0393298 |
| DENND1A | DENN/MADD domain containing 1A | -0.03726 |
| SMYD3 | SET and MYND domain containing 3 | -0.0363072 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0357579 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0353023 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0351601 |
| RPS13 | ribosomal protein S13 | -0.034564 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0345091 |
| RPS24 | ribosomal protein S24 | -0.0340334 |
| HMGA1 | high mobility group AT-hook 1 | -0.033734 |
| RPS23 | ribosomal protein S23 | -0.0337257 |
| RPL38 | ribosomal protein L38 | -0.0334446 |
| ATP9A | ATPase, class II, type 9A | -0.033437 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0333463 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0322221 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0320689 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0315233 |
| MSH4 | mutS homolog 4 | -0.0315057 |
| RPL27A | ribosomal protein L27a | -0.030985 |
| FUS | FUS RNA binding protein | -0.0309293 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0306619 |
| RPL8 | ribosomal protein L8 | -0.0305491 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0302269 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0298678 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0290762 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0288829 |
| RPLP2 | ribosomal protein, large, P2 | -0.0288784 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284443 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.028301 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0280577 |
| CALU | calumenin | -0.02755 |
| PTK2 | protein tyrosine kinase 2 | -0.0273834 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0262095 |
| RPS15 | ribosomal protein S15 | -0.0256266 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0254516 |
| CADM2 | cell adhesion molecule 2 | -0.0253347 |
| FASN | fatty acid synthase | -0.0252203 |
| RPS10 | ribosomal protein S10 | -0.0249414 |
| METTL2B | methyltransferase like 2B | -0.024898 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0247768 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0247693 |
| PARD3 | par-3 family cell polarity regulator | -0.0245266 |
| DIAPH2 | diaphanous-related formin 2 | -0.0242825 |
| RPL7A | ribosomal protein L7a | -0.0242797 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0242468 |
| RPS6 | ribosomal protein S6 | -0.0241965 |
| VIM | vimentin | -0.023957 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239544 |
| RPL13A | ribosomal protein L13a | -0.0239296 |
| FBL | fibrillarin | -0.0236839 |
| TRAF3 | TNF receptor-associated factor 3 | -0.023563 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0235492 |
| TRAP1 | TNF receptor-associated protein 1 | -0.0234121 |
| CCDC138 | coiled-coil domain containing 138 | -0.0233914 |
| EMP1 | epithelial membrane protein 1 | -0.0230948 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0229976 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0229895 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0228024 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0227938 |
| GNAS | GNAS complex locus | -0.0226962 |
| NEBL | nebulette | -0.022578 |
| RPLP1 | ribosomal protein, large, P1 | -0.0224715 |
| HMGB1 | high mobility group box 1 | -0.0219605 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0216978 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.021561 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0214873 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0213673 |
| AEBP2 | AE binding protein 2 | -0.0212352 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0210766 |
| KIAA1671 | KIAA1671 | -0.0209831 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0208434 |
| TMEM178B | transmembrane protein 178B | -0.0205474 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0202477 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0201936 |
| RPS8 | ribosomal protein S8 | -0.0200885 |
| RPS20 | ribosomal protein S20 | -0.019937 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0199004 |
| FAM193A | family with sequence similarity 193, member A | -0.0198523 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0194731 |
