| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.210926 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.135296 |
| NLGN1 | neuroligin 1 | 0.108536 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.10823 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.105203 |
| ASPH | aspartate beta-hydroxylase | 0.104063 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0957022 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0950288 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0928718 |
| GPC6 | glypican 6 | 0.0910754 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0897376 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0803365 |
| ENO1 | enolase 1, (alpha) | 0.0769944 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.072805 |
| SFTPA2 | surfactant protein A2 | 0.0696936 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0624347 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0609974 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0606064 |
| SETBP1 | SET binding protein 1 | 0.0568689 |
| CTTNBP2 | cortactin binding protein 2 | 0.0547091 |
| CALU | calumenin | 0.0532126 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0519163 |
| PRELID2 | PRELI domain containing 2 | 0.049624 |
| FMNL2 | formin-like 2 | 0.0487204 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0473694 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0462765 |
| VGF | VGF nerve growth factor inducible | 0.0442262 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0438294 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.042855 |
| VIM | vimentin | 0.0418553 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0413508 |
| ATXN1 | ataxin 1 | 0.0412289 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0409156 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0407493 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0399182 |
| PCDH7 | protocadherin 7 | 0.0394391 |
| CALR | calreticulin | 0.0377482 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0377132 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0376162 |
| ZNF638 | zinc finger protein 638 | 0.036952 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0366341 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0357042 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0348475 |
| PARVB | parvin, beta | 0.0346993 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0337683 |
| RRBP1 | ribosome binding protein 1 | 0.0336633 |
| CENPF | centromere protein F, 350/400kDa | 0.0333967 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330391 |
| VEGFA | vascular endothelial growth factor A | 0.0324783 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0317901 |
| PLIN2 | perilipin 2 | 0.031738 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309435 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0307648 |
| CANX | calnexin | 0.0303482 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.030221 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0301441 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.03013 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0296021 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0295231 |
| MSN | moesin | 0.0293526 |
| CTBP2 | C-terminal binding protein 2 | 0.029216 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0291575 |
| ZNF704 | zinc finger protein 704 | 0.0288569 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0286177 |
| ADM | adrenomedullin | 0.0285733 |
| BRD2 | bromodomain containing 2 | 0.028136 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0270123 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0269862 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0265435 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0263955 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0263849 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0262901 |
| B2M | beta-2-microglobulin | 0.0260418 |
| ACTN1 | actinin, alpha 1 | 0.0260304 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0258686 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255891 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0255454 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0252064 |
| PTMS | parathymosin | 0.0250987 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0250658 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0248965 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0247983 |
| MT2A | metallothionein 2A | 0.0247389 |
| ZYX | zyxin | 0.0246008 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0245671 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.024348 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0243407 |
| CD109 | CD109 molecule | 0.0242807 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0241017 |
| RAD51B | RAD51 paralog B | 0.0240324 |
| TPR | translocated promoter region, nuclear basket protein | 0.0237169 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0236858 |
| FLNA | filamin A, alpha | 0.0233432 |
| NAV1 | neuron navigator 1 | 0.0232297 |
| PCBP2 | poly(rC) binding protein 2 | 0.0228481 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226062 |
| MEF2A | myocyte enhancer factor 2A | 0.0224279 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0223178 |
| COPA | coatomer protein complex, subunit alpha | 0.0223173 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0223027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.453247 |
| FN1 | fibronectin 1 | -0.185525 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0839374 |
| CDC73 | cell division cycle 73 | -0.0718384 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0700947 |
| FMN1 | formin 1 | -0.0693576 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0606412 |
| HMCN1 | hemicentin 1 | -0.0553371 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.053296 |
| SRPK2 | SRSF protein kinase 2 | -0.0532367 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0532189 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0524354 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0495852 |
| TMEM123 | transmembrane protein 123 | -0.0493114 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0461402 |
| RNF145 | ring finger protein 145 | -0.0452789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0448165 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0434817 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.04248 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0423268 |
| A2M | alpha-2-macroglobulin | -0.0410833 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0401506 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.040148 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0394003 |
| DCT | dopachrome tautomerase | -0.0389964 |
| ACTG1 | actin gamma 1 | -0.0369871 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0367221 |
| GDF15 | growth differentiation factor 15 | -0.035946 |
| IER3 | immediate early response 3 | -0.0352753 |
| RHEB | Ras homolog enriched in brain | -0.0341388 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0340865 |
| TNNC1 | troponin C type 1 (slow) | -0.0337913 |
| COG5 | component of oligomeric golgi complex 5 | -0.0322871 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0320057 |
| SBF2 | SET binding factor 2 | -0.0317405 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0308474 |
| RBM33 | RNA binding motif protein 33 | -0.0307169 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0305097 |
| TPD52 | tumor protein D52 | -0.0301402 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0293004 |
| FOXJ3 | forkhead box J3 | -0.0287428 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0282817 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0278349 |
| WDR45B | WD repeat domain 45B | -0.0278314 |
| PTCHD4 | patched domain containing 4 | -0.0276246 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0270496 |
| NHSL1 | NHS-like 1 | -0.0265253 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0262458 |
| RLF | rearranged L-myc fusion | -0.0261815 |
| ZNF292 | zinc finger protein 292 | -0.0260071 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0257578 |
| NEK7 | NIMA-related kinase 7 | -0.0246631 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.024564 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0244804 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0239087 |
| HELZ | helicase with zinc finger | -0.0238742 |
| HBP1 | HMG-box transcription factor 1 | -0.0238558 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.023792 |
| USP3 | ubiquitin specific peptidase 3 | -0.0228007 |
| RPLP0 | ribosomal protein, large, P0 | -0.0227999 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0223866 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0223208 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0220113 |
| GNAS | GNAS complex locus | -0.0216719 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0216299 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0214167 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0211283 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0207961 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0207426 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0206842 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0205821 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0203924 |
| RTN4 | reticulon 4 | -0.0200573 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0200527 |
| MRTFA | myocardin related transcription factor A | -0.0195369 |
| SEC24B | SEC24 family member B | -0.0193958 |
| FRMD5 | FERM domain containing 5 | -0.0193316 |
| DMD | dystrophin | -0.0193217 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0193061 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0192794 |
| MITF | microphthalmia-associated transcription factor | -0.0192539 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0191809 |
| SYPL1 | synaptophysin-like 1 | -0.0191069 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0188742 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0186186 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0183277 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.018248 |
| NDRG1 | N-myc downstream regulated 1 | -0.0181907 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0181689 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0179424 |
| PI15 | peptidase inhibitor 15 | -0.0175539 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0175299 |
| KLHDC10 | kelch domain containing 10 | -0.0174656 |
| TNPO3 | transportin 3 | -0.0173472 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0173258 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0173178 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0173079 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0173066 |
| EHBP1 | EH domain binding protein 1 | -0.0172048 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0168483 |
