| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.179238 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.159595 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.157929 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.122205 |
| B2M | beta-2-microglobulin | 0.110403 |
| APOL1 | apolipoprotein L, 1 | 0.0790089 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0782104 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0754467 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0724606 |
| VEGFA | vascular endothelial growth factor A | 0.0700608 |
| LCN2 | lipocalin 2 | 0.0652474 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0596153 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0565244 |
| TGM2 | transglutaminase 2 | 0.0557743 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.055117 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537252 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0503989 |
| MX1 | MX dynamin-like GTPase 1 | 0.0485578 |
| LAMB3 | laminin, beta 3 | 0.0481553 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0468206 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0468107 |
| PCBP2 | poly(rC) binding protein 2 | 0.0436953 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0435165 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0427441 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0409822 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0398798 |
| SFTPA2 | surfactant protein A2 | 0.0377074 |
| MCL1 | myeloid cell leukemia 1 | 0.0371318 |
| RAD51B | RAD51 paralog B | 0.0371147 |
| TMC5 | transmembrane channel-like 5 | 0.0368568 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0368202 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0365924 |
| HLA-A | major histocompatibility complex, class I, A | 0.0363803 |
| EFNA5 | ephrin-A5 | 0.0362807 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0359612 |
| MT1E | metallothionein 1E | 0.0357227 |
| TXNIP | thioredoxin interacting protein | 0.0354049 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0347109 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0336139 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0319982 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0310061 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0309288 |
| SMAD3 | SMAD family member 3 | 0.0307685 |
| TMEM51 | transmembrane protein 51 | 0.0307072 |
| RPS17 | ribosomal protein S17 | 0.0301712 |
| RNF213 | ring finger protein 213 | 0.0298963 |
| CFB | complement factor B | 0.029307 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0292717 |
| OPTN | optineurin | 0.0292036 |
| C3 | complement component 3 | 0.0281881 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.028039 |
| DSPP | dentin sialophosphoprotein | 0.0279378 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274884 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0270316 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0266991 |
| BRD2 | bromodomain containing 2 | 0.0266081 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261408 |
| RPS12 | ribosomal protein S12 | 0.0260296 |
| ARRDC3 | arrestin domain containing 3 | 0.0258573 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0258288 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0256867 |
| DTNA | dystrobrevin, alpha | 0.0256559 |
| FAM107B | family with sequence similarity 107, member B | 0.0255719 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0253593 |
| RPS8 | ribosomal protein S8 | 0.0251276 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0249295 |
| RPL37A | ribosomal protein L37a | 0.0245627 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0243657 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0242814 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0242321 |
| CMIP | c-Maf inducing protein | 0.024024 |
| RPS3 | ribosomal protein S3 | 0.0239005 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0237293 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.023218 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0226928 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0225694 |
| MT1G | metallothionein 1G | 0.0224061 |
| BARX2 | BARX homeobox 2 | 0.0223824 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0223372 |
| SEPTIN9 | septin 9 | 0.0219995 |
| IFI44L | interferon-induced protein 44-like | 0.0217265 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0212786 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0211734 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0208137 |
| NAV2 | neuron navigator 2 | 0.0207884 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0206377 |
| KIAA1217 | KIAA1217 | 0.0206062 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0204771 |
| RPL27 | ribosomal protein L27 | 0.0202544 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0202147 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0202128 |
| RPS27 | ribosomal protein S27 | 0.0201354 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0200719 |
| RPL3 | ribosomal protein L3 | 0.0199463 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0199152 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0198826 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0197469 |
| RPS19 | ribosomal protein S19 | 0.01949 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0194685 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0194146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222156 |
| MMP7 | matrix metallopeptidase 7 | -0.141141 |
| ANXA2 | annexin A2 | -0.124576 |
| ACTG1 | actin gamma 1 | -0.116423 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.105923 |
| SPAG9 | sperm associated antigen 9 | -0.0935135 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0902091 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0883961 |
| ASPH | aspartate beta-hydroxylase | -0.0820036 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0819728 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0814269 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0806296 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0729958 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0728037 |
| RTN4 | reticulon 4 | -0.0699319 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0699258 |
| PGK1 | phosphoglycerate kinase 1 | -0.0655988 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0613366 |
| PLAU | plasminogen activator, urokinase | -0.0596998 |
| GNAS | GNAS complex locus | -0.0596105 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0595042 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0582217 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0557533 |
| RBM39 | RNA binding motif protein 39 | -0.0549452 |
| UBC | ubiquitin C | -0.0548423 |
| IER3 | immediate early response 3 | -0.0528111 |
| TMSB10 | thymosin beta 10 | -0.0527305 |
| TMEM123 | transmembrane protein 123 | -0.0526347 |
| CD2AP | CD2-associated protein | -0.0522944 |
| LAMC2 | laminin, gamma 2 | -0.0519068 |
| POTEF | POTE ankyrin domain family, member F | -0.051822 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0490037 |
| DSG2 | desmoglein 2 | -0.0472408 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0461593 |
| EREG | epiregulin | -0.0456537 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0448812 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0441689 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.043168 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0430376 |
| LDHA | lactate dehydrogenase A | -0.0425923 |
| KLF6 | Kruppel-like factor 6 | -0.042138 |
| S100A6 | S100 calcium binding protein A6 | -0.0421295 |
| TMEM263 | transmembrane protein 263 | -0.0415058 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0412791 |
| VCL | vinculin | -0.0409566 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0400575 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0397152 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0396987 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0396244 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0392767 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.038743 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0385511 |
| PTMA | prothymosin, alpha | -0.038122 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0380077 |
| FAM162A | family with sequence similarity 162, member A | -0.0375875 |
| LAMA4 | laminin, alpha 4 | -0.0373198 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0372681 |
| ACTN4 | actinin, alpha 4 | -0.0368206 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0367899 |
| RPLP0 | ribosomal protein, large, P0 | -0.0366932 |
| VIM | vimentin | -0.0360631 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0360247 |
| MEF2A | myocyte enhancer factor 2A | -0.03539 |
| RLF | rearranged L-myc fusion | -0.035251 |
| NDRG1 | N-myc downstream regulated 1 | -0.0346983 |
| ARF1 | ADP-ribosylation factor 1 | -0.0346551 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0342853 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0337653 |
| FLNB | filamin B, beta | -0.0337088 |
| LASP1 | LIM and SH3 protein 1 | -0.0334466 |
| ABI1 | abl-interactor 1 | -0.0331193 |
| CLINT1 | clathrin interactor 1 | -0.0330466 |
| SUCO | SUN domain containing ossification factor | -0.0328254 |
| CLTC | clathrin, heavy chain (Hc) | -0.0326973 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0324255 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0324249 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0322209 |
| TUBB | tubulin, beta class I | -0.0320161 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0316645 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0315285 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0312108 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0311289 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0309893 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0309397 |
| HDLBP | high density lipoprotein binding protein | -0.0302924 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0302516 |
| KRT8 | keratin 8, type II | -0.0300502 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.029581 |
| MAP1B | microtubule-associated protein 1B | -0.0294556 |
| YME1L1 | YME1-like 1 ATPase | -0.0293926 |
| BICC1 | BicC family RNA binding protein 1 | -0.0293803 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0293288 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0292885 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0288075 |
| USP3 | ubiquitin specific peptidase 3 | -0.0287233 |
| WDR45B | WD repeat domain 45B | -0.0282567 |
| SQSTM1 | sequestosome 1 | -0.0281018 |
| TXNRD1 | thioredoxin reductase 1 | -0.0280795 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0280154 |
| MUC4 | mucin 4, cell surface associated | -0.0278024 |
