| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.260576 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.154863 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.114763 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.101524 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0977975 |
| LCN2 | lipocalin 2 | 0.0944782 |
| SMAD3 | SMAD family member 3 | 0.0938644 |
| B2M | beta-2-microglobulin | 0.0918855 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0733193 |
| MYO1E | myosin IE | 0.0637885 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0631698 |
| EFNB2 | ephrin-B2 | 0.0626192 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0544852 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.05106 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0491684 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0470814 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0412565 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0410406 |
| YAP1 | Yes-associated protein 1 | 0.0407897 |
| DST | dystonin | 0.0407458 |
| RUNX1 | runt-related transcription factor 1 | 0.0395839 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0395837 |
| DUSP16 | dual specificity phosphatase 16 | 0.0395261 |
| ITGA6 | integrin, alpha 6 | 0.039299 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0387969 |
| KYNU | kynureninase | 0.0385494 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0367338 |
| ETV6 | ets variant 6 | 0.0361122 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0354168 |
| DSPP | dentin sialophosphoprotein | 0.0353366 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0352401 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0352159 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0351397 |
| PRSS22 | protease, serine, 22 | 0.0348524 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0334238 |
| PDZD8 | PDZ domain containing 8 | 0.0331777 |
| RBM47 | RNA binding motif protein 47 | 0.0323513 |
| SFTPA2 | surfactant protein A2 | 0.0317693 |
| TOX3 | TOX high mobility group box family member 3 | 0.0315897 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0314073 |
| LIMA1 | LIM domain and actin binding 1 | 0.0300702 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0298471 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0297764 |
| VEGFA | vascular endothelial growth factor A | 0.0296859 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0296179 |
| MYO5B | myosin VB | 0.0292398 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0291684 |
| MLPH | melanophilin | 0.0291134 |
| SLK | STE20-like kinase | 0.0285551 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0280694 |
| ATP10B | ATPase, class V, type 10B | 0.0279739 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0271035 |
| FAT1 | FAT atypical cadherin 1 | 0.026851 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0264763 |
| XDH | xanthine dehydrogenase | 0.0263892 |
| CLDN4 | claudin 4 | 0.026204 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0261283 |
| DIAPH1 | diaphanous-related formin 1 | 0.025694 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0256658 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0254663 |
| RNF43 | ring finger protein 43 | 0.0249748 |
| MT2A | metallothionein 2A | 0.0247961 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0245827 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242007 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0240257 |
| KIAA1217 | KIAA1217 | 0.0237399 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0228634 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0228358 |
| CD58 | CD58 molecule | 0.0220055 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0220032 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0219389 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0218689 |
| BCL2L1 | BCL2-like 1 | 0.0218165 |
| TRIM2 | tripartite motif containing 2 | 0.0217411 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0215973 |
| HKDC1 | hexokinase domain containing 1 | 0.0214206 |
| ZFP36 | ZFP36 ring finger protein | 0.0210996 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0208342 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0206046 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0205829 |
| RPS12 | ribosomal protein S12 | 0.0205143 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.020282 |
| CTBP2 | C-terminal binding protein 2 | 0.0201042 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0200697 |
| FNIP2 | folliculin interacting protein 2 | 0.0200486 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0198471 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0197722 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0196307 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0194764 |
| TPI1 | triosephosphate isomerase 1 | 0.0193449 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0192879 |
| CCNL1 | cyclin L1 | 0.019286 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0191876 |
| ATF4 | activating transcription factor 4 | 0.0190815 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190467 |
| CDHR2 | cadherin-related family member 2 | 0.019041 |
| TMEM51 | transmembrane protein 51 | 0.0190051 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0187994 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0186669 |
| PCDH1 | protocadherin 1 | 0.0186457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.130682 |
| LYZ | lysozyme | -0.123911 |
| INTS6 | integrator complex subunit 6 | -0.118693 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.117857 |
| XAF1 | XIAP associated factor 1 | -0.11056 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.105593 |
| PHF3 | PHD finger protein 3 | -0.0966621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0930374 |
| NPSR1 | neuropeptide S receptor 1 | -0.0926004 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0854823 |
| PLSCR2 | phospholipid scramblase 2 | -0.0832425 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0825317 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0776044 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0734785 |
| RIGI | RNA sensor RIG-I | -0.0726468 |
| EGR1 | early growth response 1 | -0.0713172 |
| MUC20 | mucin 20, cell surface associated | -0.0651501 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0636006 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0631163 |
| HLA-B | major histocompatibility complex, class I, B | -0.0613997 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0595362 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0582149 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0581426 |
| VCL | vinculin | -0.0573601 |
| SP100 | SP100 nuclear antigen | -0.0562903 |
| PLSCR1 | phospholipid scramblase 1 | -0.0554248 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0518072 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.050785 |
| NCKAP5 | NCK-associated protein 5 | -0.0493108 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0486356 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0477213 |
| GOLGB1 | golgin B1 | -0.0477105 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0473141 |
| HLA-E | major histocompatibility complex, class I, E | -0.047153 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0471458 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0466746 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0457539 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0450204 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0450016 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0441487 |
| SQSTM1 | sequestosome 1 | -0.043174 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0431601 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0429346 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0428757 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0424533 |
| NF1 | neurofibromin 1 | -0.0417388 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0415863 |
| TNS4 | tensin 4 | -0.0411709 |
| PTMA | prothymosin, alpha | -0.0408274 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0407936 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405493 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0395384 |
| NCOA7 | nuclear receptor coactivator 7 | -0.039173 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0390298 |
| TFRC | transferrin receptor | -0.0385638 |
| MORF4L2 | mortality factor 4 like 2 | -0.0384637 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0383632 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0383309 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0380321 |
| ACTG1 | actin gamma 1 | -0.037846 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0378358 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0375044 |
| POU2F2 | POU class 2 homeobox 2 | -0.0374418 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0371805 |
| ARF1 | ADP-ribosylation factor 1 | -0.0369055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0368163 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0367795 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0367434 |
| PMP22 | peripheral myelin protein 22 | -0.0358466 |
| RAD51B | RAD51 paralog B | -0.0357899 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0354616 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.034778 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0347378 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0347359 |
| UBC | ubiquitin C | -0.0340818 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0340361 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0335824 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0335709 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0333182 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0332848 |
| TUFT1 | tuftelin 1 | -0.0332715 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0330936 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0328981 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0327481 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0326709 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0326388 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0323484 |
| PRKCA | protein kinase C, alpha | -0.0321398 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0321351 |
| MAP7 | microtubule-associated protein 7 | -0.0320744 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0320628 |
| RPS24 | ribosomal protein S24 | -0.0319575 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0318543 |
| COG6 | component of oligomeric golgi complex 6 | -0.0318179 |
| AHI1 | Abelson helper integration site 1 | -0.0316355 |
| ZNF609 | zinc finger protein 609 | -0.0315784 |
| RPL34 | ribosomal protein L34 | -0.0310646 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0309598 |
| GNAS | GNAS complex locus | -0.030889 |
| UBAP2 | ubiquitin associated protein 2 | -0.0305352 |
