| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.156359 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0696819 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0690641 |
| KYNU | kynureninase | 0.0656219 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0463356 |
| STC1 | stanniocalcin 1 | 0.0425317 |
| ZNF638 | zinc finger protein 638 | 0.0406608 |
| MKI67 | marker of proliferation Ki-67 | 0.040545 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0367282 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.035252 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0335886 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0333016 |
| FAM13A | family with sequence similarity 13, member A | 0.0325645 |
| TXNRD1 | thioredoxin reductase 1 | 0.0325449 |
| NAV2 | neuron navigator 2 | 0.0315469 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0296282 |
| MYO10 | myosin X | 0.0289657 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0278163 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0275049 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0273444 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.026939 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0266441 |
| SQSTM1 | sequestosome 1 | 0.0257317 |
| GRAMD1B | GRAM domain containing 1B | 0.0255085 |
| SMAD3 | SMAD family member 3 | 0.0249678 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248522 |
| METTL15 | methyltransferase like 15 | 0.0244044 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0240724 |
| CTSB | cathepsin B | 0.0236929 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0235584 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0226976 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0226041 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0225356 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0218451 |
| PCBP2 | poly(rC) binding protein 2 | 0.0218023 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0217484 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0216248 |
| TLN1 | talin 1 | 0.0215526 |
| YTHDC1 | YTH domain containing 1 | 0.0215357 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0213323 |
| RNF216 | ring finger protein 216 | 0.0212812 |
| FLNA | filamin A, alpha | 0.0212597 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0212056 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0211224 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0209386 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0208649 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0206417 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0203339 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0196468 |
| CENPF | centromere protein F, 350/400kDa | 0.0195622 |
| HELZ | helicase with zinc finger | 0.0195207 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193576 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0191833 |
| VEGFC | vascular endothelial growth factor C | 0.0191158 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0190208 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0185096 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0184949 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0183997 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0180186 |
| JUN | jun proto-oncogene | 0.0179371 |
| KIAA1217 | KIAA1217 | 0.0169851 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.0169596 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0169398 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0169369 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0168932 |
| UBE3C | ubiquitin protein ligase E3C | 0.0165697 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0165561 |
| WDR26 | WD repeat domain 26 | 0.0165114 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0165109 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0165071 |
| AOPEP | aminopeptidase O (putative) | 0.0163455 |
| PCDHB16 | protocadherin beta 16 | 0.0162969 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | 0.0160899 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0160353 |
| PLEC | plectin | 0.0158751 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0157631 |
| RPL3 | ribosomal protein L3 | 0.0156691 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0156416 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0156016 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0155288 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0150809 |
| PCNT | pericentrin | 0.0150638 |
| DNMBP | dynamin binding protein | 0.0149993 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0148892 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0148627 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0147977 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0147878 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.014786 |
| CEP192 | centrosomal protein 192kDa | 0.0147857 |
| DUSP16 | dual specificity phosphatase 16 | 0.0147358 |
| NLGN1 | neuroligin 1 | 0.0143475 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | 0.0142851 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0142276 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0142136 |
| TXNIP | thioredoxin interacting protein | 0.0140876 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0140361 |
| FAM219A | family with sequence similarity 219, member A | 0.0140283 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0139974 |
| USP36 | ubiquitin specific peptidase 36 | 0.0139852 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0139372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.3471 |
| VIM | vimentin | -0.119766 |
| TMSB10 | thymosin beta 10 | -0.117517 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.107258 |
| FN1 | fibronectin 1 | -0.105369 |
| MT2A | metallothionein 2A | -0.0927303 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0871433 |
| NDRG1 | N-myc downstream regulated 1 | -0.0804737 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.080215 |
| FTL | ferritin, light polypeptide | -0.0782283 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0776214 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0749718 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0674929 |
| ASPH | aspartate beta-hydroxylase | -0.0586626 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0570626 |
| HLA-B | major histocompatibility complex, class I, B | -0.0537069 |
| POTEF | POTE ankyrin domain family, member F | -0.0522925 |
| VCL | vinculin | -0.0511881 |
| LOX | lysyl oxidase | -0.0509019 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0500854 |
| LDHA | lactate dehydrogenase A | -0.0497423 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0481893 |
| EGR1 | early growth response 1 | -0.0476081 |
| RTN4 | reticulon 4 | -0.0457039 |
| RPL35A | ribosomal protein L35a | -0.0452345 |
| DTNA | dystrobrevin, alpha | -0.0446543 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0435387 |
| TPM4 | tropomyosin 4 | -0.0425075 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0419171 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0414356 |
| IGF2 | insulin-like growth factor 2 | -0.0408938 |
| PTMA | prothymosin, alpha | -0.0406688 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0403845 |
| S100A10 | S100 calcium binding protein A10 | -0.0392313 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0386411 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0381397 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0363218 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0357502 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0351162 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0348388 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347168 |
| RPS24 | ribosomal protein S24 | -0.0345827 |
| PKM | pyruvate kinase, muscle | -0.034434 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0341927 |
| RPL9 | ribosomal protein L9 | -0.0339366 |
| GNAS | GNAS complex locus | -0.0335202 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0334544 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0330659 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0330215 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0329327 |
| S100A6 | S100 calcium binding protein A6 | -0.0321712 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.032153 |
| ZNF804A | zinc finger protein 804A | -0.0321191 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0319323 |
| RPS8 | ribosomal protein S8 | -0.0310546 |
| HMGA1 | high mobility group AT-hook 1 | -0.0305487 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0305358 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302353 |
| CALD1 | caldesmon 1 | -0.0300208 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0298926 |
| CALR | calreticulin | -0.0291539 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0289097 |
| OXR1 | oxidation resistance 1 | -0.0286535 |
| NAV1 | neuron navigator 1 | -0.0285466 |
| ENO1 | enolase 1, (alpha) | -0.0285235 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0281703 |
| EGFR | epidermal growth factor receptor | -0.027762 |
| ACTG1 | actin gamma 1 | -0.0275459 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0270516 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0268328 |
| TNS3 | tensin 3 | -0.0267443 |
| HLA-C | major histocompatibility complex, class I, C | -0.0264813 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0259921 |
| RPL37A | ribosomal protein L37a | -0.0257069 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0252769 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0251403 |
| PGK1 | phosphoglycerate kinase 1 | -0.025084 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0244873 |
| CAVIN1 | caveolae associated protein 1 | -0.0244669 |
| SDC4 | syndecan 4 | -0.0244239 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0243459 |
| RPL31 | ribosomal protein L31 | -0.0242821 |
| MMP12 | matrix metallopeptidase 12 | -0.0241837 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0240231 |
| RPL27A | ribosomal protein L27a | -0.0237187 |
| GPC6 | glypican 6 | -0.023672 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0235422 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0233422 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0227869 |
| WASF2 | WAS protein family, member 2 | -0.0227323 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0227061 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.02266 |
| DIAPH2 | diaphanous-related formin 2 | -0.0225552 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0225295 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0225048 |
| CLIC4 | chloride intracellular channel 4 | -0.0221785 |
| TAGLN2 | transgelin 2 | -0.0220846 |
| CD99 | CD99 molecule | -0.0220637 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0220438 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0216048 |
