| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.07262 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0689797 |
| TPM3 | tropomyosin 3 | 0.0655899 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0616985 |
| GOLGA4 | golgin A4 | 0.052388 |
| RPS12 | ribosomal protein S12 | 0.0519639 |
| PCBP2 | poly(rC) binding protein 2 | 0.0501315 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0471975 |
| RPS3 | ribosomal protein S3 | 0.0436832 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0435914 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0427498 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0392794 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0390598 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0370162 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0358552 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0354359 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0343135 |
| TPI1 | triosephosphate isomerase 1 | 0.0340919 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333268 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0322287 |
| ATF4 | activating transcription factor 4 | 0.0321457 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0316415 |
| RBM39 | RNA binding motif protein 39 | 0.0313223 |
| MIDN | midnolin | 0.0311159 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0309062 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0305281 |
| SCFD1 | sec1 family domain containing 1 | 0.0300537 |
| TJP1 | tight junction protein 1 | 0.0298425 |
| TPR | translocated promoter region, nuclear basket protein | 0.0296455 |
| VMP1 | vacuole membrane protein 1 | 0.0284038 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0283997 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0277394 |
| TMF1 | TATA element modulatory factor 1 | 0.0274235 |
| SON | SON DNA binding protein | 0.0273328 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0271324 |
| RBM25 | RNA binding motif protein 25 | 0.0271247 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0269064 |
| ZFP36 | ZFP36 ring finger protein | 0.0258483 |
| HDAC8 | histone deacetylase 8 | 0.0258343 |
| COG6 | component of oligomeric golgi complex 6 | 0.0257169 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0255835 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0255278 |
| SET | SET nuclear proto-oncogene | 0.0254676 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0250798 |
| RPS2 | ribosomal protein S2 | 0.0247792 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242675 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0242088 |
| MT2A | metallothionein 2A | 0.024113 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0237693 |
| FLNA | filamin A, alpha | 0.0236323 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0236034 |
| ZNF638 | zinc finger protein 638 | 0.0235992 |
| B2M | beta-2-microglobulin | 0.0235477 |
| GPX4 | glutathione peroxidase 4 | 0.0234364 |
| YTHDC1 | YTH domain containing 1 | 0.0234021 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0232603 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | 0.022917 |
| RPS7 | ribosomal protein S7 | 0.0228849 |
| CCNL1 | cyclin L1 | 0.022826 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0226406 |
| KIF1B | kinesin family member 1B | 0.0224034 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0223877 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0223102 |
| ARRDC3 | arrestin domain containing 3 | 0.0222377 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.022189 |
| GOLGB1 | golgin B1 | 0.0221675 |
| TXNIP | thioredoxin interacting protein | 0.0216245 |
| RPL3 | ribosomal protein L3 | 0.0215893 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0215718 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0215036 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.021369 |
| SECISBP2L | SECIS binding protein 2-like | 0.0213519 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0213352 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0213171 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0212335 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0212295 |
| MLEC | malectin | 0.0211112 |
| RPS4X | ribosomal protein S4, X-linked | 0.021013 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0208285 |
| JMJD1C | jumonji domain containing 1C | 0.0207424 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0207237 |
| RACK1 | receptor for activated C kinase 1 | 0.02055 |
| RPL26 | ribosomal protein L26 | 0.0205305 |
| CDK19 | cyclin-dependent kinase 19 | 0.0205246 |
| SERINC1 | serine incorporator 1 | 0.0202905 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0202304 |
| TLN1 | talin 1 | 0.020155 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0201544 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0201537 |
| TMSB10 | thymosin beta 10 | 0.0199564 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0198584 |
| ANGPTL4 | angiopoietin-like 4 | 0.0197899 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0197429 |
| CWC15 | CWC15 spliceosome-associated protein | 0.0197319 |
| VEGFA | vascular endothelial growth factor A | 0.019699 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0194823 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0194821 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0194763 |
| RBM26 | RNA binding motif protein 26 | 0.0194113 |
| TMEM59 | transmembrane protein 59 | 0.0192849 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.276269 |
| PTMA | prothymosin, alpha | -0.168391 |
| AHNAK | AHNAK nucleoprotein | -0.153934 |
| FAT1 | FAT atypical cadherin 1 | -0.150219 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11111 |
| ACTG1 | actin gamma 1 | -0.0972963 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.083596 |
| RPS24 | ribosomal protein S24 | -0.063871 |
| TPM4 | tropomyosin 4 | -0.0635494 |
| KRT8 | keratin 8, type II | -0.0608231 |
| TUBA1B | tubulin, alpha 1b | -0.0607905 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0592041 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0590783 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0589283 |
| MKI67 | marker of proliferation Ki-67 | -0.0577498 |
| S100A10 | S100 calcium binding protein A10 | -0.056896 |
| HMGB1 | high mobility group box 1 | -0.0538275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0535337 |
| RPS8 | ribosomal protein S8 | -0.0522749 |
| SERINC5 | serine incorporator 5 | -0.0509806 |
| CCND1 | cyclin D1 | -0.0492603 |
| NDRG1 | N-myc downstream regulated 1 | -0.0490522 |
| SMC4 | structural maintenance of chromosomes 4 | -0.048073 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0473122 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0469625 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0462899 |
| FHIT | fragile histidine triad | -0.0461151 |
| HMGA2 | high mobility group AT-hook 2 | -0.0446814 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0443523 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0442191 |
| TUBB | tubulin, beta class I | -0.0433874 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0425819 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0421291 |
| RPL7A | ribosomal protein L7a | -0.0409181 |
| PTK2 | protein tyrosine kinase 2 | -0.0409086 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0398745 |
| RPS11 | ribosomal protein S11 | -0.0398232 |
| RPL8 | ribosomal protein L8 | -0.0384522 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0382118 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0381131 |
| TAOK1 | TAO kinase 1 | -0.0377948 |
| S100A6 | S100 calcium binding protein A6 | -0.0375832 |
| HDLBP | high density lipoprotein binding protein | -0.0372533 |
| LOC112694756 | uncharaterized LOC112694756 | -0.036967 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0369272 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0368445 |
| RPL34 | ribosomal protein L34 | -0.0366094 |
| ENO1 | enolase 1, (alpha) | -0.0364856 |
| PKM | pyruvate kinase, muscle | -0.0364638 |
| ANLN | anillin, actin binding protein | -0.036301 |
| RPL38 | ribosomal protein L38 | -0.0361364 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0361341 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0355877 |
| LMNA | lamin A/C | -0.0355588 |
| DIAPH3 | diaphanous-related formin 3 | -0.0349157 |
| TMEM123 | transmembrane protein 123 | -0.034514 |
| RPS25 | ribosomal protein S25 | -0.0344224 |
| WWOX | WW domain containing oxidoreductase | -0.034402 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0343356 |
| CADPS | Ca++-dependent secretion activator | -0.0340284 |
| RPS23 | ribosomal protein S23 | -0.0337917 |
| CD2AP | CD2-associated protein | -0.0334627 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327781 |
| FUS | FUS RNA binding protein | -0.0327147 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0325176 |
| RPS6 | ribosomal protein S6 | -0.0321895 |
| CENPF | centromere protein F, 350/400kDa | -0.0320277 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0315962 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.031379 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0313347 |
| MCL1 | myeloid cell leukemia 1 | -0.0313318 |
| RPL32 | ribosomal protein L32 | -0.0312642 |
| RPL6 | ribosomal protein L6 | -0.0311762 |
| DSG2 | desmoglein 2 | -0.0299597 |
| SEPTIN10 | septin 10 | -0.0299524 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0297024 |
| XPO1 | exportin 1 | -0.0293339 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.02933 |
| RPS21 | ribosomal protein S21 | -0.0292107 |
| RAD51B | RAD51 paralog B | -0.0290885 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0290119 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0288506 |
| MYOF | myoferlin | -0.0288275 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288016 |
| NF1 | neurofibromin 1 | -0.0287262 |
| GNAS | GNAS complex locus | -0.0287007 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0286739 |
| SMYD3 | SET and MYND domain containing 3 | -0.0285482 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284751 |
| ZNRF3 | zinc and ring finger 3 | -0.0282112 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0281357 |
| EXPH5 | exophilin 5 | -0.0280423 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0280182 |
| MYO9A | myosin IXA | -0.0278622 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.027604 |
| RPS29 | ribosomal protein S29 | -0.027446 |
| DEK | DEK proto-oncogene | -0.0271748 |
| MSI2 | musashi RNA-binding protein 2 | -0.0271541 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0267232 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.026619 |
