| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.133647 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0786332 |
| FLNA | filamin A, alpha | 0.0767824 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0702835 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0694066 |
| GOLGB1 | golgin B1 | 0.0565693 |
| PCBP2 | poly(rC) binding protein 2 | 0.0534292 |
| ZNF638 | zinc finger protein 638 | 0.0527553 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0505298 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.048729 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0475304 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0474702 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0454872 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0449831 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0430786 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0419899 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0416689 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0412125 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0408412 |
| INTS6 | integrator complex subunit 6 | 0.0408079 |
| PRRC2C | proline-rich coiled-coil 2C | 0.040646 |
| PTMA | prothymosin, alpha | 0.0394587 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0392775 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0386183 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.036933 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0368696 |
| PLEC | plectin | 0.0343491 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328603 |
| RNF213 | ring finger protein 213 | 0.0327789 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0322942 |
| LAMB3 | laminin, beta 3 | 0.032109 |
| SMAD3 | SMAD family member 3 | 0.0318398 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0315814 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0314883 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0310624 |
| CTBP2 | C-terminal binding protein 2 | 0.0310623 |
| DIAPH1 | diaphanous-related formin 1 | 0.030942 |
| TJP1 | tight junction protein 1 | 0.0309357 |
| HELZ | helicase with zinc finger | 0.0307549 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.030309 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0302737 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0301625 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296065 |
| VIM | vimentin | 0.0295099 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0295033 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0284047 |
| TMF1 | TATA element modulatory factor 1 | 0.0280526 |
| ATXN1 | ataxin 1 | 0.0280426 |
| EZR | ezrin | 0.0280229 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0274825 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0272001 |
| RCOR1 | REST corepressor 1 | 0.0271293 |
| PAX8 | paired box 8 | 0.026596 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0259772 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259327 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.025891 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.025829 |
| VEGFA | vascular endothelial growth factor A | 0.025575 |
| SFTPA2 | surfactant protein A2 | 0.0252792 |
| RUNX1 | runt-related transcription factor 1 | 0.0252214 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0252089 |
| NDRG1 | N-myc downstream regulated 1 | 0.0251927 |
| WWOX | WW domain containing oxidoreductase | 0.0251891 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0249681 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0248572 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0247119 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0246551 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0240708 |
| MED13 | mediator complex subunit 13 | 0.0239786 |
| RBM39 | RNA binding motif protein 39 | 0.0239658 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0238986 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0236951 |
| MT2A | metallothionein 2A | 0.023676 |
| ANXA11 | annexin A11 | 0.0234947 |
| RBM5 | RNA binding motif protein 5 | 0.0234788 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0233788 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0229923 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0229884 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0229411 |
| PGM3 | phosphoglucomutase 3 | 0.0225462 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0225417 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0224077 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0223104 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0222217 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0221756 |
| COPA | coatomer protein complex, subunit alpha | 0.0220696 |
| COG6 | component of oligomeric golgi complex 6 | 0.0219372 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0218666 |
| KIF5B | kinesin family member 5B | 0.0218394 |
| MYEOV | myeloma overexpressed | 0.0215188 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0214122 |
| RPL37A | ribosomal protein L37a | 0.0213879 |
| EFNA5 | ephrin-A5 | 0.0213875 |
| PCM1 | pericentriolar material 1 | 0.0212636 |
| RPS29 | ribosomal protein S29 | 0.0211938 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0210915 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0210295 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0210203 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0209258 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0207576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.194133 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.131192 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0701313 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0680805 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0589247 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0572399 |
| RPLP0 | ribosomal protein, large, P0 | -0.0569455 |
| ACTG1 | actin gamma 1 | -0.0562593 |
| LDHA | lactate dehydrogenase A | -0.055196 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0543606 |
| AHNAK | AHNAK nucleoprotein | -0.0466083 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0455212 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0418225 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0417379 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0397941 |
| KRT7 | keratin 7, type II | -0.0397939 |
| TPM4 | tropomyosin 4 | -0.0393518 |
| GNAS | GNAS complex locus | -0.0382988 |
| ANXA2 | annexin A2 | -0.0377664 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0372412 |
| VCAN | versican | -0.0371614 |
| VCL | vinculin | -0.0370182 |
| RPL32 | ribosomal protein L32 | -0.0362997 |
| HMGA2 | high mobility group AT-hook 2 | -0.0357885 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0352237 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.034481 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329129 |
| RPL19 | ribosomal protein L19 | -0.0327058 |
| TMSB10 | thymosin beta 10 | -0.0326224 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0323939 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0322981 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310927 |
| TUBB | tubulin, beta class I | -0.0310867 |
| KRT19 | keratin 19, type I | -0.0304218 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0292822 |
| S100A6 | S100 calcium binding protein A6 | -0.0292748 |
| CD44 | CD44 molecule (Indian blood group) | -0.0290354 |
| PCED1B | PC-esterase domain containing 1B | -0.0285695 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0284314 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0282416 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0282311 |
| EREG | epiregulin | -0.0282051 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0281692 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0280948 |
| FTL | ferritin, light polypeptide | -0.0280844 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0280747 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0278874 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.027844 |
| TUBA1B | tubulin, alpha 1b | -0.0276919 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0271264 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0259291 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0257694 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0257163 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0255241 |
| RPS5 | ribosomal protein S5 | -0.0254529 |
| ZNF292 | zinc finger protein 292 | -0.0250777 |
| DPP4 | dipeptidyl-peptidase 4 | -0.0245964 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245946 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0244159 |
| FIGN | fidgetin | -0.0235217 |
| S100A10 | S100 calcium binding protein A10 | -0.0230115 |
| PFN1 | profilin 1 | -0.0228719 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0228671 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0228535 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0224819 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0224701 |
| DSG2 | desmoglein 2 | -0.0222545 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.02215 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0220124 |
| LAMC2 | laminin, gamma 2 | -0.0218832 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0217904 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0217824 |
| S100A4 | S100 calcium binding protein A4 | -0.0216478 |
| CAPNS1 | calpain, small subunit 1 | -0.0215717 |
| NF1 | neurofibromin 1 | -0.0214712 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0214099 |
| PARD3 | par-3 family cell polarity regulator | -0.0213376 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0212376 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0210381 |
| MAP4 | microtubule-associated protein 4 | -0.0209802 |
| SEPTIN10 | septin 10 | -0.0208639 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0207603 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0205904 |
| EMP1 | epithelial membrane protein 1 | -0.0202827 |
| RPL34 | ribosomal protein L34 | -0.0201333 |
| CCND1 | cyclin D1 | -0.0201313 |
| ARF1 | ADP-ribosylation factor 1 | -0.0199854 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0199628 |
| SBF2 | SET binding factor 2 | -0.0198393 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0195735 |
| ATG7 | autophagy related 7 | -0.019571 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0193632 |
| CLDN1 | claudin 1 | -0.0192494 |
| CDCP1 | CUB domain containing protein 1 | -0.0191516 |
| WDR45B | WD repeat domain 45B | -0.0190969 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0190021 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0187159 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0184428 |
| KRT18 | keratin 18, type I | -0.0182381 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0182327 |
