| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine (maleate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.301196 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.177535 |
| CD44 | CD44 molecule (Indian blood group) | 0.177502 |
| MT2A | metallothionein 2A | 0.147928 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.142016 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.127072 |
| TMSB10 | thymosin beta 10 | 0.11234 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.11158 |
| ENO1 | enolase 1, (alpha) | 0.0926998 |
| MAP1B | microtubule-associated protein 1B | 0.0801715 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0778938 |
| LDHA | lactate dehydrogenase A | 0.0737149 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0697614 |
| RPL12 | ribosomal protein L12 | 0.0682099 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0678493 |
| NDRG1 | N-myc downstream regulated 1 | 0.0666376 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0635403 |
| TPI1 | triosephosphate isomerase 1 | 0.0632595 |
| STC1 | stanniocalcin 1 | 0.0551286 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0519218 |
| AXL | AXL receptor tyrosine kinase | 0.0513116 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0499917 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0486638 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0482081 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0469153 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0431268 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0416822 |
| CENPF | centromere protein F, 350/400kDa | 0.0412616 |
| PGK1 | phosphoglycerate kinase 1 | 0.040709 |
| VEGFA | vascular endothelial growth factor A | 0.0371384 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0369794 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0366607 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0364632 |
| FAM13A | family with sequence similarity 13, member A | 0.0357267 |
| YBX1 | Y box binding protein 1 | 0.0355388 |
| RACK1 | receptor for activated C kinase 1 | 0.0349797 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345947 |
| RPS4X | ribosomal protein S4, X-linked | 0.0336894 |
| ANGPTL4 | angiopoietin-like 4 | 0.0335895 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0333035 |
| RPS2 | ribosomal protein S2 | 0.033003 |
| MSN | moesin | 0.032184 |
| RPS12 | ribosomal protein S12 | 0.0310161 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0308259 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0307734 |
| B2M | beta-2-microglobulin | 0.0302863 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296886 |
| G0S2 | G0/G1 switch 2 | 0.0295688 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0293083 |
| PCBP2 | poly(rC) binding protein 2 | 0.0290794 |
| MT1X | metallothionein 1X | 0.0289247 |
| RPS19 | ribosomal protein S19 | 0.0285794 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0285 |
| TXNIP | thioredoxin interacting protein | 0.0280304 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279876 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0274709 |
| PLEC | plectin | 0.0268023 |
| RRM2 | ribonucleotide reductase M2 | 0.0265029 |
| TPM3 | tropomyosin 3 | 0.026425 |
| RPS3 | ribosomal protein S3 | 0.0262258 |
| SFTPA2 | surfactant protein A2 | 0.0257436 |
| PKM | pyruvate kinase, muscle | 0.025619 |
| RPL23 | ribosomal protein L23 | 0.0254146 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0252404 |
| LAMB3 | laminin, beta 3 | 0.0248624 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0248617 |
| VIM | vimentin | 0.0248157 |
| TMSB4X | thymosin beta 4, X-linked | 0.0246829 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0245297 |
| DUSP6 | dual specificity phosphatase 6 | 0.0244992 |
| RPS17 | ribosomal protein S17 | 0.0243576 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0239145 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0238616 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0232394 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0229506 |
| RPL3 | ribosomal protein L3 | 0.0229349 |
| RPS7 | ribosomal protein S7 | 0.0225454 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0218919 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0218426 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0214985 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0213471 |
| SON | SON DNA binding protein | 0.0210063 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0209833 |
| IRS2 | insulin receptor substrate 2 | 0.0209213 |
| GRAMD1B | GRAM domain containing 1B | 0.0207583 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0206791 |
| CDCP1 | CUB domain containing protein 1 | 0.0206157 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0204666 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0202122 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0199854 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0199226 |
| RPS14 | ribosomal protein S14 | 0.0198973 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0198156 |
| CLIC1 | chloride intracellular channel 1 | 0.0198148 |
| DSPP | dentin sialophosphoprotein | 0.0193771 |
| AHNAK | AHNAK nucleoprotein | 0.0193751 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.01936 |
| RPL7 | ribosomal protein L7 | 0.0193049 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0190957 |
| MKI67 | marker of proliferation Ki-67 | 0.0189486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.152836 |
| IGF2 | insulin-like growth factor 2 | -0.126374 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0985261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0961846 |
| ACTG1 | actin gamma 1 | -0.0878979 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0844773 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0759994 |
| ASPH | aspartate beta-hydroxylase | -0.075088 |
| HMGA2 | high mobility group AT-hook 2 | -0.0647996 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0598021 |
| COL1A1 | collagen, type I, alpha 1 | -0.058915 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0561454 |
| COL5A1 | collagen, type V, alpha 1 | -0.054142 |
| RAI14 | retinoic acid induced 14 | -0.0530208 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.052399 |
| FN1 | fibronectin 1 | -0.0512752 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0510744 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0488299 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0485516 |
| NAV1 | neuron navigator 1 | -0.0446566 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0444455 |
| CAVIN1 | caveolae associated protein 1 | -0.0419817 |
| CLMP | CXADR-like membrane protein | -0.0415999 |
| VCL | vinculin | -0.0413557 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0398825 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0366591 |
| FMN1 | formin 1 | -0.036656 |
| CUX1 | cut-like homeobox 1 | -0.0355568 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0350845 |
| PTK2 | protein tyrosine kinase 2 | -0.0341885 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0338193 |
| FRMD4A | FERM domain containing 4A | -0.0337957 |
| JMJD1C | jumonji domain containing 1C | -0.0335439 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.033278 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.032955 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0324535 |
| DIAPH2 | diaphanous-related formin 2 | -0.0315852 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0313551 |
| EGR1 | early growth response 1 | -0.0308936 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0308091 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0306447 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0299829 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0299072 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0298011 |
| IER3 | immediate early response 3 | -0.0295139 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0282847 |
| MAP4 | microtubule-associated protein 4 | -0.028233 |
| BPTF | bromodomain PHD finger transcription factor | -0.027593 |
| TUBB6 | tubulin, beta 6 class V | -0.0275629 |
| RPL38 | ribosomal protein L38 | -0.0274327 |
| GNAS | GNAS complex locus | -0.0271405 |
| PCBP3 | poly(rC) binding protein 3 | -0.0270463 |
| RPS24 | ribosomal protein S24 | -0.0268214 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0267421 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0264918 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0261335 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0261298 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0259853 |
| ATXN1 | ataxin 1 | -0.025634 |
| ATG7 | autophagy related 7 | -0.0255227 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0252823 |
| LOX | lysyl oxidase | -0.0250558 |
| TPM1 | tropomyosin 1 (alpha) | -0.0249254 |
| GLIS3 | GLIS family zinc finger 3 | -0.0248611 |
| GLG1 | golgi glycoprotein 1 | -0.0244479 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0239783 |
| TENM2 | teneurin transmembrane protein 2 | -0.0238892 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0236083 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0235431 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0235272 |
| RIN2 | Ras and Rab interactor 2 | -0.0234493 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0232211 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0231689 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.023158 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0230247 |
| MYO10 | myosin X | -0.022983 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.022769 |
| LRRC23 | leucine rich repeat containing 23 | -0.0227191 |
| NABP1 | nucleic acid binding protein 1 | -0.0226356 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0225413 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0224312 |
| HIP1 | huntingtin interacting protein 1 | -0.0224068 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0223634 |
| ZNF609 | zinc finger protein 609 | -0.0221931 |
| TMEM263 | transmembrane protein 263 | -0.0218135 |
| HM13 | histocompatibility (minor) 13 | -0.0217459 |
| HLA-B | major histocompatibility complex, class I, B | -0.0214261 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0214218 |
| COL7A1 | collagen, type VII, alpha 1 | -0.021397 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0213779 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0213005 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0212234 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0212154 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0210046 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0210028 |
| PCNX4 | pecanex 4 | -0.0209446 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.020815 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0207219 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0203152 |
