| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.175415 |
| VEGFA | vascular endothelial growth factor A | 0.13757 |
| CDH13 | cadherin 13 | 0.105595 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.105046 |
| NDRG1 | N-myc downstream regulated 1 | 0.102781 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0934552 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0924 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0866015 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0787632 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0787248 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0749124 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0570569 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0549759 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0533622 |
| EGFR | epidermal growth factor receptor | 0.051486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0509415 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0487304 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0485976 |
| CADM1 | cell adhesion molecule 1 | 0.0479264 |
| COL5A1 | collagen, type V, alpha 1 | 0.0457804 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0429584 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0415802 |
| FMNL2 | formin-like 2 | 0.0394327 |
| GOLGB1 | golgin B1 | 0.0382687 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0370379 |
| NAV2 | neuron navigator 2 | 0.0369448 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0368434 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0350075 |
| ATF4 | activating transcription factor 4 | 0.0343662 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0338414 |
| PLEC | plectin | 0.0326725 |
| EFNA5 | ephrin-A5 | 0.031657 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.031618 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031187 |
| SFTPA2 | surfactant protein A2 | 0.0311595 |
| BRD2 | bromodomain containing 2 | 0.030453 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0299141 |
| RND3 | Rho family GTPase 3 | 0.0291456 |
| PGM3 | phosphoglucomutase 3 | 0.028738 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0286583 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0285471 |
| HDAC9 | histone deacetylase 9 | 0.0285392 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284969 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0278342 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0271263 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0254139 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0252012 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.024433 |
| FBN1 | fibrillin 1 | 0.0242451 |
| CALR | calreticulin | 0.0242261 |
| CTBP2 | C-terminal binding protein 2 | 0.0241345 |
| SFPQ | splicing factor proline/glutamine-rich | 0.024128 |
| SON | SON DNA binding protein | 0.0238692 |
| ATXN1 | ataxin 1 | 0.0234003 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231916 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0223015 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222643 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0222444 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0221385 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0220837 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0220537 |
| AHNAK | AHNAK nucleoprotein | 0.0215967 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0215732 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0215095 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0214832 |
| RPS3 | ribosomal protein S3 | 0.021321 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0212507 |
| RUNX1 | runt-related transcription factor 1 | 0.0212327 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0211445 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0210507 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0207118 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0205535 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203761 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0200798 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0199675 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0197451 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0196831 |
| FNIP1 | folliculin interacting protein 1 | 0.0196573 |
| SQSTM1 | sequestosome 1 | 0.0196556 |
| MYO10 | myosin X | 0.0196505 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0196475 |
| ZNF638 | zinc finger protein 638 | 0.0193907 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0193627 |
| INTS6 | integrator complex subunit 6 | 0.0193009 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0192265 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0190987 |
| HYOU1 | hypoxia up-regulated 1 | 0.0190049 |
| TNS1 | tensin 1 | 0.01897 |
| ASPH | aspartate beta-hydroxylase | 0.0188986 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.01887 |
| APP | amyloid beta (A4) precursor protein | 0.0188544 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0184107 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0184029 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0183632 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0181719 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0181402 |
| RPL37A | ribosomal protein L37a | 0.0180379 |
| JUN | jun proto-oncogene | 0.0180342 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0179384 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0177152 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.446726 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.249321 |
| COL1A1 | collagen, type I, alpha 1 | -0.210061 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118442 |
| COL1A2 | collagen, type I, alpha 2 | -0.11136 |
| TPM4 | tropomyosin 4 | -0.109636 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0979263 |
| VIM | vimentin | -0.0965004 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0924796 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0819537 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.073711 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0686569 |
| ATP13A3 | ATPase type 13A3 | -0.064704 |
| IER3 | immediate early response 3 | -0.0619741 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0587379 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0562717 |
| CD44 | CD44 molecule (Indian blood group) | -0.0562716 |
| POSTN | periostin, osteoblast specific factor | -0.0521172 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0442815 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0436899 |
| VCAN | versican | -0.0418022 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0414406 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0412862 |
| LOX | lysyl oxidase | -0.0406108 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0395476 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0395426 |
| LOXL2 | lysyl oxidase-like 2 | -0.0395011 |
| ACTG1 | actin gamma 1 | -0.0391868 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0387012 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0385845 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0381965 |
| CLIC4 | chloride intracellular channel 4 | -0.0379017 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0377786 |
| MAP1B | microtubule-associated protein 1B | -0.0376531 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0374584 |
| GNAS | GNAS complex locus | -0.0345871 |
| TAPBP | TAP binding protein (tapasin) | -0.0341239 |
| ZNF292 | zinc finger protein 292 | -0.0323529 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0323262 |
| IL6ST | interleukin 6 signal transducer | -0.0321135 |
| KPNB1 | karyopherin (importin) beta 1 | -0.032072 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0320576 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.031974 |
| CAVIN1 | caveolae associated protein 1 | -0.0316663 |
| PXDN | peroxidasin | -0.0315118 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0312585 |
| SRGN | serglycin | -0.0310756 |
| TRAM1 | translocation associated membrane protein 1 | -0.0309333 |
| SMAD3 | SMAD family member 3 | -0.0308571 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0302662 |
| EHD2 | EH-domain containing 2 | -0.0298176 |
| LDHA | lactate dehydrogenase A | -0.02969 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0295414 |
| SQLE | squalene epoxidase | -0.0288121 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0288112 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0287881 |
| CALD1 | caldesmon 1 | -0.0281359 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0280538 |
| HMGA2 | high mobility group AT-hook 2 | -0.0278551 |
| RPLP0 | ribosomal protein, large, P0 | -0.0274683 |
| ANXA2 | annexin A2 | -0.026706 |
| ECE1 | endothelin converting enzyme 1 | -0.0264324 |
| TUBB | tubulin, beta class I | -0.0261586 |
| CD99 | CD99 molecule | -0.0255109 |
| NRP1 | neuropilin 1 | -0.0253318 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0248521 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0248052 |
| TMEM123 | transmembrane protein 123 | -0.0245605 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0245369 |
| SBF2 | SET binding factor 2 | -0.0244123 |
| S100A6 | S100 calcium binding protein A6 | -0.0241133 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0240258 |
| PTMA | prothymosin, alpha | -0.023598 |
| NREP | neuronal regeneration related protein | -0.0232228 |
| RPL8 | ribosomal protein L8 | -0.0231307 |
| PALLD | palladin, cytoskeletal associated protein | -0.0230371 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0224893 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0223282 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0221932 |
| OSMR | oncostatin M receptor | -0.0218193 |
| ACTN4 | actinin, alpha 4 | -0.0216422 |
| SEPTIN7 | septin 7 | -0.0215227 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0213981 |
| WASF2 | WAS protein family, member 2 | -0.0213243 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.021269 |
| TPM2 | tropomyosin 2 (beta) | -0.021159 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.020996 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0209953 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.020968 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0209218 |
| KLF6 | Kruppel-like factor 6 | -0.0208986 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0208655 |
| PKM | pyruvate kinase, muscle | -0.0208378 |
| HLA-B | major histocompatibility complex, class I, B | -0.0206891 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0205292 |
| THY1 | Thy-1 cell surface antigen | -0.0203676 |
| FRMD4A | FERM domain containing 4A | -0.020365 |
| RTN4 | reticulon 4 | -0.0200558 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0197341 |
| HMGA1 | high mobility group AT-hook 1 | -0.0194645 |
