| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.13539 |
| INTS6 | integrator complex subunit 6 | 0.124954 |
| CTBP2 | C-terminal binding protein 2 | 0.080626 |
| SMAD3 | SMAD family member 3 | 0.0681386 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0662677 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0597938 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0577903 |
| LMO7 | LIM domain 7 | 0.0570337 |
| VEGFA | vascular endothelial growth factor A | 0.0471675 |
| PDLIM5 | PDZ and LIM domain 5 | 0.042938 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.040949 |
| EGFR | epidermal growth factor receptor | 0.040768 |
| NDRG1 | N-myc downstream regulated 1 | 0.0403543 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0381554 |
| NTN4 | netrin 4 | 0.0380696 |
| CCNYL1 | cyclin Y-like 1 | 0.0380508 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.03699 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0343583 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.034304 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.033676 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0324606 |
| FNDC3B | fibronectin type III domain containing 3B | 0.032399 |
| PRR5L | proline rich 5 like | 0.0313239 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0309194 |
| TLE4 | transducin-like enhancer of split 4 | 0.030468 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0304512 |
| WLS | wntless Wnt ligand secretion mediator | 0.0301928 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.029719 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0292614 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0292156 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289072 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0286335 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0269676 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0268354 |
| MYOF | myoferlin | 0.0268179 |
| PCBP2 | poly(rC) binding protein 2 | 0.0267488 |
| FAM13A | family with sequence similarity 13, member A | 0.0265062 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264967 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0250392 |
| AEBP2 | AE binding protein 2 | 0.0240137 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0237412 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0236833 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0236291 |
| ATXN1 | ataxin 1 | 0.0231068 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0224756 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0223531 |
| NEBL | nebulette | 0.0221644 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0220424 |
| ADM | adrenomedullin | 0.0220147 |
| ZNF638 | zinc finger protein 638 | 0.0219766 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0219426 |
| EPS8L1 | EPS8-like 1 | 0.0217624 |
| UTRN | utrophin | 0.0215655 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0214415 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0212812 |
| PDE10A | phosphodiesterase 10A | 0.0211914 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.021172 |
| FOXO3 | forkhead box O3 | 0.0210509 |
| DUSP16 | dual specificity phosphatase 16 | 0.0208529 |
| FMNL2 | formin-like 2 | 0.0208264 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0205181 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0204504 |
| HOMER1 | homer scaffolding protein 1 | 0.0203958 |
| SERTAD2 | SERTA domain containing 2 | 0.0201695 |
| MYEOV | myeloma overexpressed | 0.0197965 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0196486 |
| YAP1 | Yes-associated protein 1 | 0.0195349 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0192293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0191548 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0190739 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0189665 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0188152 |
| PLEC | plectin | 0.0188116 |
| CMIP | c-Maf inducing protein | 0.018638 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0186315 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0185687 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0181649 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0181394 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.018119 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0180097 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.017691 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0175276 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0174464 |
| FBXO32 | F-box protein 32 | 0.0173882 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0173709 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0170493 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0169091 |
| PLK2 | polo-like kinase 2 | 0.0168928 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.016877 |
| POF1B | premature ovarian failure, 1B | 0.0168212 |
| DNHD1 | dynein heavy chain domain 1 | 0.0167926 |
| RPL37A | ribosomal protein L37a | 0.0166677 |
| MED13L | mediator complex subunit 13-like | 0.0165527 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0164989 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0163292 |
| ATOSA | atos homolog A | 0.0161243 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.016098 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0160598 |
| FBXO11 | F-box protein 11 | 0.0159004 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0158151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.132743 |
| TXNRD1 | thioredoxin reductase 1 | -0.128237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.126749 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115678 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.100612 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0955711 |
| LYZ | lysozyme | -0.0829236 |
| ACTG1 | actin gamma 1 | -0.0820408 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.075443 |
| S100A6 | S100 calcium binding protein A6 | -0.0726921 |
| PTK2 | protein tyrosine kinase 2 | -0.0721 |
| RPLP1 | ribosomal protein, large, P1 | -0.0625007 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0603564 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.057703 |
| ANXA2 | annexin A2 | -0.055489 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0523514 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0520109 |
| RPLP0 | ribosomal protein, large, P0 | -0.0517903 |
| TMEM123 | transmembrane protein 123 | -0.0509667 |
| RPS24 | ribosomal protein S24 | -0.0502024 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0484888 |
| ACTN4 | actinin, alpha 4 | -0.0481961 |
| DIAPH2 | diaphanous-related formin 2 | -0.0477254 |
| RPL34 | ribosomal protein L34 | -0.0475715 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.047192 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0468683 |
| EGR1 | early growth response 1 | -0.0466193 |
| WWC1 | WW and C2 domain containing 1 | -0.0463376 |
| HDLBP | high density lipoprotein binding protein | -0.0460732 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0452271 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0444208 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0439825 |
| SDC4 | syndecan 4 | -0.0424536 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0419436 |
| WASF2 | WAS protein family, member 2 | -0.0414858 |
| RPL27A | ribosomal protein L27a | -0.0414715 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0413625 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0412436 |
| KRT18 | keratin 18, type I | -0.0408379 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0405455 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0405067 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0401209 |
| FRY | furry homolog (Drosophila) | -0.0399996 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0395963 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0393619 |
| MKI67 | marker of proliferation Ki-67 | -0.0390102 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0389572 |
| CD2AP | CD2-associated protein | -0.0388624 |
| FTL | ferritin, light polypeptide | -0.0388423 |
| RPL4 | ribosomal protein L4 | -0.0386975 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0378009 |
| LDHA | lactate dehydrogenase A | -0.0376065 |
| SQSTM1 | sequestosome 1 | -0.0368106 |
| NF1 | neurofibromin 1 | -0.0366709 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0362933 |
| TRAM1 | translocation associated membrane protein 1 | -0.0356967 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.035638 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0354624 |
| MMP7 | matrix metallopeptidase 7 | -0.0343808 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0338187 |
| ZNF292 | zinc finger protein 292 | -0.0336445 |
| RPL12 | ribosomal protein L12 | -0.0336007 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0332741 |
| TRIB1 | tribbles pseudokinase 1 | -0.0332033 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0328428 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0327391 |
| RNF213 | ring finger protein 213 | -0.0327223 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0327021 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0323899 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0323027 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0321352 |
| ASPH | aspartate beta-hydroxylase | -0.0318282 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0316862 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0314113 |
| S100A10 | S100 calcium binding protein A10 | -0.0312909 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0312455 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0310256 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.030788 |
| JMJD1C | jumonji domain containing 1C | -0.0307448 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0302348 |
| ABHD2 | abhydrolase domain containing 2 | -0.0295515 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0294863 |
| RPS21 | ribosomal protein S21 | -0.0292804 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0290608 |
| RPS16 | ribosomal protein S16 | -0.0287354 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0286222 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0286035 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0285755 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0284742 |
| DGKH | diacylglycerol kinase, eta | -0.0283937 |
| DEK | DEK proto-oncogene | -0.0283501 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0282789 |
| POTEF | POTE ankyrin domain family, member F | -0.0281996 |
| HMGA1 | high mobility group AT-hook 1 | -0.0280038 |
| ENO1 | enolase 1, (alpha) | -0.0275131 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0274199 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0271616 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0271584 |
| KIF5B | kinesin family member 5B | -0.0270929 |
| ETV6 | ets variant 6 | -0.0269514 |
