| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.340034 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.251198 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.228176 |
| MT2A | metallothionein 2A | 0.175659 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.169662 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.125003 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.107992 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0976654 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0974793 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0503432 |
| CD44 | CD44 molecule (Indian blood group) | 0.050308 |
| ZNF841 | zinc finger protein 841 | 0.0502947 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.047716 |
| TMSB4X | thymosin beta 4, X-linked | 0.0449975 |
| ENO1 | enolase 1, (alpha) | 0.0445875 |
| FLNB | filamin B, beta | 0.0430312 |
| FLNA | filamin A, alpha | 0.0422447 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0396599 |
| PCBP2 | poly(rC) binding protein 2 | 0.0394813 |
| MT1X | metallothionein 1X | 0.0391925 |
| YBX1 | Y box binding protein 1 | 0.0382199 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0381026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0380164 |
| JUN | jun proto-oncogene | 0.0373396 |
| TPM3 | tropomyosin 3 | 0.037276 |
| ADM | adrenomedullin | 0.0363398 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0357989 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0342573 |
| SET | SET nuclear proto-oncogene | 0.0336501 |
| RPL23 | ribosomal protein L23 | 0.0333351 |
| LDHA | lactate dehydrogenase A | 0.0333003 |
| VEGFA | vascular endothelial growth factor A | 0.0330668 |
| AHNAK | AHNAK nucleoprotein | 0.0322389 |
| SMC1A | structural maintenance of chromosomes 1A | 0.031161 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0308884 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0308371 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0303886 |
| EGFR | epidermal growth factor receptor | 0.0302134 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0301105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.029989 |
| ANXA1 | annexin A1 | 0.0298484 |
| RPL12 | ribosomal protein L12 | 0.0294977 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0286897 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0286489 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0283024 |
| ACTN1 | actinin, alpha 1 | 0.0281981 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0281226 |
| RPS3 | ribosomal protein S3 | 0.0281165 |
| CANX | calnexin | 0.0279949 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0279001 |
| SFTPA2 | surfactant protein A2 | 0.02788 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0278622 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0278247 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.027655 |
| NAV2 | neuron navigator 2 | 0.0272741 |
| MSN | moesin | 0.0270007 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262616 |
| RACK1 | receptor for activated C kinase 1 | 0.0254023 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.025118 |
| TPI1 | triosephosphate isomerase 1 | 0.0250585 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0243435 |
| DTNA | dystrobrevin, alpha | 0.0241188 |
| PODXL | podocalyxin-like | 0.0240841 |
| RPL35A | ribosomal protein L35a | 0.0240715 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0233397 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.022961 |
| TLN1 | talin 1 | 0.0224932 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0213122 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0208555 |
| RPL26 | ribosomal protein L26 | 0.02083 |
| STC2 | stanniocalcin 2 | 0.0207245 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0205844 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0203975 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0202763 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.020197 |
| ARRDC3 | arrestin domain containing 3 | 0.0198739 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0193804 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.019369 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193374 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.019238 |
| RUNX1 | runt-related transcription factor 1 | 0.0191185 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0190379 |
| CLIC1 | chloride intracellular channel 1 | 0.0187637 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0185027 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0181294 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0181212 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0181106 |
| RAI1 | retinoic acid induced 1 | 0.0178122 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0177493 |
| ANXA2 | annexin A2 | 0.0177415 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0177151 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0177073 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0176586 |
| EFNA5 | ephrin-A5 | 0.0174221 |
| RPS12 | ribosomal protein S12 | 0.0171632 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0167535 |
| RPL3 | ribosomal protein L3 | 0.016637 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0165324 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0164749 |
| RPS2 | ribosomal protein S2 | 0.0164121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.208527 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.194692 |
| FN1 | fibronectin 1 | -0.179798 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.138756 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.123937 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0838011 |
| EXT1 | exostosin glycosyltransferase 1 | -0.078815 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0645445 |
| PLCB4 | phospholipase C, beta 4 | -0.0632229 |
| FTL | ferritin, light polypeptide | -0.0592655 |
| DEK | DEK proto-oncogene | -0.0535352 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0474028 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.047311 |
| DIAPH3 | diaphanous-related formin 3 | -0.047305 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.046292 |
| CTSD | cathepsin D | -0.0433947 |
| ACTG1 | actin gamma 1 | -0.0429643 |
| POSTN | periostin, osteoblast specific factor | -0.0428322 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0416243 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0400856 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0396418 |
| TGFB2 | transforming growth factor, beta 2 | -0.039326 |
| ZNF804A | zinc finger protein 804A | -0.0383076 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0377941 |
| POTEF | POTE ankyrin domain family, member F | -0.0374434 |
| TXNRD1 | thioredoxin reductase 1 | -0.0366024 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0355066 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0348539 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0346482 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.034195 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0337462 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0328209 |
| TUBB | tubulin, beta class I | -0.0317136 |
| GOLT1B | golgi transport 1B | -0.0311293 |
| GLIS3 | GLIS family zinc finger 3 | -0.0307076 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0304447 |
| CLTC | clathrin, heavy chain (Hc) | -0.0296939 |
| IL6ST | interleukin 6 signal transducer | -0.029529 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0291511 |
| FSTL1 | follistatin-like 1 | -0.0284934 |
| TRAM1 | translocation associated membrane protein 1 | -0.0276163 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0275657 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0272698 |
| MAP4 | microtubule-associated protein 4 | -0.0271559 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0269968 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0268704 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0268507 |
| SBF2 | SET binding factor 2 | -0.0261515 |
| GNAS | GNAS complex locus | -0.0257618 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0255874 |
| SULF1 | sulfatase 1 | -0.0249856 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0249121 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0247865 |
| HLA-A | major histocompatibility complex, class I, A | -0.0245501 |
| TUBA1B | tubulin, alpha 1b | -0.0245178 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0238897 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0237912 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0231877 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0231271 |
| ZXDC | ZXD family zinc finger C | -0.0230152 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0229971 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0229601 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0226945 |
| TNS3 | tensin 3 | -0.0226806 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0224786 |
| SQSTM1 | sequestosome 1 | -0.0220635 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0220174 |
| CD99 | CD99 molecule | -0.0219201 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0218289 |
| SETD5 | SET domain containing 5 | -0.0218056 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0217888 |
| RHEB | Ras homolog enriched in brain | -0.0216809 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0215305 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215159 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0213498 |
| NUP98 | nucleoporin 98kDa | -0.0210674 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0210463 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0210216 |
| RPL27A | ribosomal protein L27a | -0.0208891 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.020408 |
| TPX2 | TPX2, microtubule-associated | -0.0203065 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0202887 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0198613 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0198023 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0197252 |
| NKTR | natural killer cell triggering receptor | -0.0197168 |
| NUP153 | nucleoporin 153kDa | -0.0193214 |
| OSMR | oncostatin M receptor | -0.0193196 |
| PPME1 | protein phosphatase methylesterase 1 | -0.019282 |
| TENM3 | teneurin transmembrane protein 3 | -0.0192197 |
| FAM193A | family with sequence similarity 193, member A | -0.01906 |
| PTK2 | protein tyrosine kinase 2 | -0.0189695 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.018915 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0188474 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0188319 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0185972 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0185224 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0183967 |
| RPS23 | ribosomal protein S23 | -0.0182233 |
| VCL | vinculin | -0.0180774 |
