| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.156943 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.096434 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0944479 |
| LMO7 | LIM domain 7 | 0.0873858 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0825694 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0764104 |
| FAT1 | FAT atypical cadherin 1 | 0.0667594 |
| ONECUT3 | one cut homeobox 3 | 0.0586887 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0558283 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0553913 |
| MT2A | metallothionein 2A | 0.0499248 |
| RPS12 | ribosomal protein S12 | 0.0493604 |
| RPL26 | ribosomal protein L26 | 0.0476374 |
| CD44 | CD44 molecule (Indian blood group) | 0.0422966 |
| H1-0 | H1.0 linker histone | 0.0416209 |
| ASPH | aspartate beta-hydroxylase | 0.0414099 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0403046 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0395444 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.039225 |
| PRELID2 | PRELI domain containing 2 | 0.0382238 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0373797 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0371944 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0360029 |
| PDZD8 | PDZ domain containing 8 | 0.0358741 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0349476 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.034714 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0346131 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0344501 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0335044 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0324304 |
| RPS3 | ribosomal protein S3 | 0.031292 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0303652 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0293766 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0289596 |
| AHNAK | AHNAK nucleoprotein | 0.028857 |
| B2M | beta-2-microglobulin | 0.0283642 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0283393 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.028287 |
| NEBL | nebulette | 0.0281767 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.027685 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0276099 |
| RPS2 | ribosomal protein S2 | 0.0275439 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0272932 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0267292 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0266528 |
| PTMA | prothymosin, alpha | 0.0266393 |
| SON | SON DNA binding protein | 0.0264888 |
| RRBP1 | ribosome binding protein 1 | 0.0260536 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0260291 |
| DSPP | dentin sialophosphoprotein | 0.0259388 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0258864 |
| FHIT | fragile histidine triad | 0.0256507 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0252144 |
| DUSP16 | dual specificity phosphatase 16 | 0.0252102 |
| POF1B | premature ovarian failure, 1B | 0.0251308 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0250448 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0248723 |
| AFDN | afadin, adherens junction formation factor | 0.0247348 |
| RPL12 | ribosomal protein L12 | 0.0245938 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.024331 |
| FOXP1 | forkhead box P1 | 0.0242185 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0240538 |
| EGFR | epidermal growth factor receptor | 0.0237677 |
| RPS19 | ribosomal protein S19 | 0.0236142 |
| GOLGB1 | golgin B1 | 0.0235918 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0235002 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0234582 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0232797 |
| MUC13 | mucin 13, cell surface associated | 0.0230805 |
| PDE10A | phosphodiesterase 10A | 0.0229342 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0228826 |
| SMAD2 | SMAD family member 2 | 0.0223313 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0221469 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.021995 |
| APP | amyloid beta (A4) precursor protein | 0.0215934 |
| CLIC1 | chloride intracellular channel 1 | 0.0214163 |
| MYO1E | myosin IE | 0.0206366 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0203834 |
| CCNL2 | cyclin L2 | 0.0202944 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0200668 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0199677 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0198804 |
| INTS6 | integrator complex subunit 6 | 0.0197172 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0196429 |
| SFTPA2 | surfactant protein A2 | 0.0196112 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0195049 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0194252 |
| RPL18 | ribosomal protein L18 | 0.0194086 |
| CTBP2 | C-terminal binding protein 2 | 0.0193077 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0191585 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0190694 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0190241 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0189506 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.018919 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0188367 |
| H1-4 | H1.4 linker histone, cluster member | 0.0187679 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0186118 |
| SQSTM1 | sequestosome 1 | 0.0184851 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0182236 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0180989 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.337671 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.232855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.12835 |
| NPSR1 | neuropeptide S receptor 1 | -0.124483 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.111348 |
| ANXA2 | annexin A2 | -0.110629 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.10317 |
| RPS6 | ribosomal protein S6 | -0.0802529 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0788775 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0716316 |
| FLNB | filamin B, beta | -0.0651487 |
| TPM4 | tropomyosin 4 | -0.0644216 |
| NDRG1 | N-myc downstream regulated 1 | -0.0622943 |
| POTEF | POTE ankyrin domain family, member F | -0.0618891 |
| MUC17 | mucin 17, cell surface associated | -0.0607545 |
| TNS4 | tensin 4 | -0.0580409 |
| PIGR | polymeric immunoglobulin receptor | -0.057702 |
| S100A6 | S100 calcium binding protein A6 | -0.057362 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0550932 |
| CALB1 | calbindin 1, 28kDa | -0.0521388 |
| PERP | PERP, TP53 apoptosis effector | -0.0517479 |
| ACTG1 | actin gamma 1 | -0.0505846 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0490243 |
| ITGB4 | integrin, beta 4 | -0.0477757 |
| FOSL1 | FOS-like antigen 1 | -0.0476165 |
| HMGA1 | high mobility group AT-hook 1 | -0.0441734 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0426437 |
| ACTN4 | actinin, alpha 4 | -0.042248 |
| EZR | ezrin | -0.0405949 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0396052 |
| RPLP0 | ribosomal protein, large, P0 | -0.0391488 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0386162 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0383356 |
| TXNIP | thioredoxin interacting protein | -0.0381601 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0375749 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0362302 |
| ZNF292 | zinc finger protein 292 | -0.0353704 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0350038 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0340966 |
| GDF15 | growth differentiation factor 15 | -0.0339807 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0339659 |
| FERMT1 | fermitin family member 1 | -0.0330377 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0328005 |
| S100A10 | S100 calcium binding protein A10 | -0.0327159 |
| GOLGA4 | golgin A4 | -0.0326296 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0321399 |
| USP3 | ubiquitin specific peptidase 3 | -0.0316655 |
| DEK | DEK proto-oncogene | -0.0314742 |
| SETD5 | SET domain containing 5 | -0.0313211 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0311707 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310204 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0307635 |
| UBC | ubiquitin C | -0.0303326 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0302067 |
| TMEM123 | transmembrane protein 123 | -0.0301414 |
| LDHA | lactate dehydrogenase A | -0.0299385 |
| CCNI | cyclin I | -0.0295805 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0295616 |
| WDR45B | WD repeat domain 45B | -0.0295408 |
| RPS25 | ribosomal protein S25 | -0.0293825 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0293255 |
| SBF2 | SET binding factor 2 | -0.029052 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0288749 |
| GNAS | GNAS complex locus | -0.0288702 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0285594 |
| FAM13A | family with sequence similarity 13, member A | -0.0284693 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0282015 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0281308 |
| ABHD2 | abhydrolase domain containing 2 | -0.0279813 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0276973 |
| WASF2 | WAS protein family, member 2 | -0.0276756 |
| INSIG1 | insulin induced gene 1 | -0.0274464 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0273463 |
| SRPK1 | SRSF protein kinase 1 | -0.0272155 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0267899 |
| EGR1 | early growth response 1 | -0.0267814 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0267782 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0267469 |
| VCL | vinculin | -0.0264318 |
| RIN2 | Ras and Rab interactor 2 | -0.0262886 |
| EMP1 | epithelial membrane protein 1 | -0.026224 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0261591 |
| EREG | epiregulin | -0.0261124 |
| TFG | TRK-fused gene | -0.0259717 |
| VMP1 | vacuole membrane protein 1 | -0.0259095 |
| KRT19 | keratin 19, type I | -0.0256366 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0255068 |
| RPS23 | ribosomal protein S23 | -0.0254579 |
| RTN4 | reticulon 4 | -0.0253704 |
| RPL34 | ribosomal protein L34 | -0.0252368 |
| CDCP1 | CUB domain containing protein 1 | -0.0251663 |
| FNBP1L | formin binding protein 1-like | -0.024884 |
| MLEC | malectin | -0.0248249 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0248197 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0247664 |
| EXOC1 | exocyst complex component 1 | -0.024675 |
| SNX9 | sorting nexin 9 | -0.0246628 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | -0.0245815 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0245579 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0245416 |
