| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.0864316 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.08169 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0582829 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0580883 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0572577 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0496315 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0469315 |
| ASPH | aspartate beta-hydroxylase | 0.0468617 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0428744 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0417599 |
| EGFR | epidermal growth factor receptor | 0.0403209 |
| FRMD5 | FERM domain containing 5 | 0.0396347 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | 0.0396256 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0393597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.038706 |
| RPS3 | ribosomal protein S3 | 0.0362639 |
| LRRC23 | leucine rich repeat containing 23 | 0.0338174 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0329843 |
| WWOX | WW domain containing oxidoreductase | 0.0322455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0319302 |
| PRELID2 | PRELI domain containing 2 | 0.0313515 |
| PDZD8 | PDZ domain containing 8 | 0.0306864 |
| RPS12 | ribosomal protein S12 | 0.0306755 |
| CTBP2 | C-terminal binding protein 2 | 0.0305401 |
| NABP1 | nucleic acid binding protein 1 | 0.0296273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0290847 |
| IFRD1 | interferon-related developmental regulator 1 | 0.029071 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0287995 |
| SKP1 | S-phase kinase-associated protein 1 | 0.028723 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0282165 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0277392 |
| AHNAK | AHNAK nucleoprotein | 0.0273188 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0273013 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0268457 |
| PGK1 | phosphoglycerate kinase 1 | 0.0264916 |
| FUS | FUS RNA binding protein | 0.0262885 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0259125 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0255089 |
| NPTN | neuroplastin | 0.0250521 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.024797 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0247896 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0246534 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0243396 |
| TPI1 | triosephosphate isomerase 1 | 0.0240677 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0234472 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0228523 |
| RPL18 | ribosomal protein L18 | 0.0226729 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0226253 |
| ZNF638 | zinc finger protein 638 | 0.0224804 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0224782 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0223342 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.022274 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0222342 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0220351 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.0217306 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0212904 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0212398 |
| RCC1 | regulator of chromosome condensation 1 | 0.0210123 |
| HDLBP | high density lipoprotein binding protein | 0.02073 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0205404 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0204581 |
| AEBP2 | AE binding protein 2 | 0.0204338 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0204306 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0204095 |
| MSH4 | mutS homolog 4 | 0.0195973 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0194306 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0190187 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0188576 |
| SETX | senataxin | 0.0186236 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0185758 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.018531 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0184607 |
| HOMER1 | homer scaffolding protein 1 | 0.018386 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0183752 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0183114 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0182129 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0179884 |
| RPS19 | ribosomal protein S19 | 0.017937 |
| APP | amyloid beta (A4) precursor protein | 0.0178834 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0178353 |
| MT2A | metallothionein 2A | 0.0177682 |
| MACROD2 | MACRO domain containing 2 | 0.017738 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0176873 |
| SLC38A2 | solute carrier family 38, member 2 | 0.017595 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0173818 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0172875 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0171339 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0170591 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0169973 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0168573 |
| SERINC5 | serine incorporator 5 | 0.0167907 |
| MORF4L2 | mortality factor 4 like 2 | 0.0166601 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0166133 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0164104 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0163212 |
| DST | dystonin | 0.0159218 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0159045 |
| RACK1 | receptor for activated C kinase 1 | 0.0158786 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0158729 |
| DAPK1 | death-associated protein kinase 1 | 0.0158499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.147227 |
| RPS6 | ribosomal protein S6 | -0.142465 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.138644 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12162 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.119732 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0960097 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0896019 |
| VCL | vinculin | -0.0810708 |
| PRSS3 | protease, serine, 3 | -0.0805852 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0757329 |
| CALB1 | calbindin 1, 28kDa | -0.072197 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0696029 |
| TXNRD1 | thioredoxin reductase 1 | -0.0693578 |
| TJP1 | tight junction protein 1 | -0.0648055 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0647445 |
| DSG3 | desmoglein 3 | -0.0640242 |
| RPLP1 | ribosomal protein, large, P1 | -0.0597556 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0595157 |
| ITGA6 | integrin, alpha 6 | -0.0592757 |
| PKP2 | plakophilin 2 | -0.0591546 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0573333 |
| TRIM2 | tripartite motif containing 2 | -0.0561819 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.054315 |
| LAMA4 | laminin, alpha 4 | -0.0534835 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0531378 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0528983 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0518885 |
| GOLGA4 | golgin A4 | -0.0514429 |
| RPLP0 | ribosomal protein, large, P0 | -0.0507368 |
| ETNK1 | ethanolamine kinase 1 | -0.0499649 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0498227 |
| WWC1 | WW and C2 domain containing 1 | -0.0491404 |
| ACTG1 | actin gamma 1 | -0.0482112 |
| SHROOM3 | shroom family member 3 | -0.0479575 |
| SNX9 | sorting nexin 9 | -0.0470663 |
| MYOF | myoferlin | -0.0467523 |
| RPS25 | ribosomal protein S25 | -0.0467213 |
| ANXA11 | annexin A11 | -0.0463781 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0452854 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0451092 |
| FOXO1 | forkhead box O1 | -0.0449122 |
| HLA-B | major histocompatibility complex, class I, B | -0.0446334 |
| RIGI | RNA sensor RIG-I | -0.0438683 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0436831 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0436735 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0420274 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0409072 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0406711 |
| DIAPH1 | diaphanous-related formin 1 | -0.0404182 |
| ACTN4 | actinin, alpha 4 | -0.0402321 |
| CLDN4 | claudin 4 | -0.0401851 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0391194 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0390097 |
| PLAC8 | placenta-specific 8 | -0.0388247 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0386436 |
| RPL34 | ribosomal protein L34 | -0.0385862 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0378697 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0378207 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0371308 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0370029 |
| POTEF | POTE ankyrin domain family, member F | -0.0368138 |
| RPS23 | ribosomal protein S23 | -0.0367024 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0365797 |
| ANXA2 | annexin A2 | -0.0360782 |
| PCDHB16 | protocadherin beta 16 | -0.0360335 |
| MX2 | MX dynamin-like GTPase 2 | -0.035814 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0351908 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0351536 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0350139 |
| FERMT1 | fermitin family member 1 | -0.034725 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.034125 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0340589 |
| RTN4 | reticulon 4 | -0.0340185 |
| NOSTRIN | nitric oxide synthase trafficking | -0.0336047 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0332156 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0327621 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0320891 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0317377 |
| LAMC2 | laminin, gamma 2 | -0.0317318 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0317072 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.031655 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0315811 |
| EGR1 | early growth response 1 | -0.0314452 |
| EREG | epiregulin | -0.0311598 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0299362 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.029767 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0297273 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0297223 |
| TMEM45B | transmembrane protein 45B | -0.0295552 |
| USP15 | ubiquitin specific peptidase 15 | -0.0292269 |
| PTEN | phosphatase and tensin homolog | -0.0290318 |
| RPL13A | ribosomal protein L13a | -0.0286879 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284782 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0282915 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.028263 |
| RPS8 | ribosomal protein S8 | -0.0281845 |
| EPHA2 | EPH receptor A2 | -0.0281795 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0280045 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.028002 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0277561 |
