| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.104504 |
| LMO7 | LIM domain 7 | 0.0971408 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0842552 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0818363 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0791597 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0789732 |
| TMSB10 | thymosin beta 10 | 0.0683833 |
| LAMC2 | laminin, gamma 2 | 0.0645696 |
| STC1 | stanniocalcin 1 | 0.0637704 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0621623 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0585792 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0582734 |
| MCL1 | myeloid cell leukemia 1 | 0.0570409 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0486795 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0474197 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0473233 |
| AREG | amphiregulin | 0.0469433 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0466082 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0461788 |
| GRAMD1B | GRAM domain containing 1B | 0.0456432 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0443503 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0422729 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0417218 |
| MT2A | metallothionein 2A | 0.0415308 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0411602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0405659 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0402017 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0385841 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0383582 |
| PTMA | prothymosin, alpha | 0.038307 |
| BMP6 | bone morphogenetic protein 6 | 0.0380751 |
| INTS6 | integrator complex subunit 6 | 0.0379894 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0374911 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0359344 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0351513 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0349535 |
| LAMA4 | laminin, alpha 4 | 0.0344702 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0337219 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0334928 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0330871 |
| RPL35A | ribosomal protein L35a | 0.0314468 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310849 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0309902 |
| EGR1 | early growth response 1 | 0.0301481 |
| RPS3 | ribosomal protein S3 | 0.0299017 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0295468 |
| LAMB3 | laminin, beta 3 | 0.0294625 |
| TOP1 | topoisomerase (DNA) I | 0.0288153 |
| RPL37A | ribosomal protein L37a | 0.0276972 |
| CST3 | cystatin C | 0.0275328 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0271425 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0270243 |
| SEC61G | Sec61 gamma subunit | 0.0266436 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0258565 |
| MYO1E | myosin IE | 0.025836 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0257818 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0250691 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0242986 |
| CPE | carboxypeptidase E | 0.0240422 |
| HOMER1 | homer scaffolding protein 1 | 0.0240084 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0226089 |
| S100A10 | S100 calcium binding protein A10 | 0.0221988 |
| DIAPH1 | diaphanous-related formin 1 | 0.0220608 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0217743 |
| S100P | S100 calcium binding protein P | 0.0216732 |
| SVIL | supervillin | 0.0214905 |
| DSPP | dentin sialophosphoprotein | 0.0214586 |
| RPS12 | ribosomal protein S12 | 0.0214558 |
| RNF149 | ring finger protein 149 | 0.0213626 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0209448 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0209107 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0208435 |
| ANXA1 | annexin A1 | 0.0205547 |
| IRS2 | insulin receptor substrate 2 | 0.0204182 |
| CD163L1 | CD163 molecule-like 1 | 0.0202449 |
| TJP1 | tight junction protein 1 | 0.0198251 |
| EZR | ezrin | 0.0195823 |
| CTSL | cathepsin L | 0.0193498 |
| TPM4 | tropomyosin 4 | 0.0192841 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0192606 |
| SPAG9 | sperm associated antigen 9 | 0.0192334 |
| SIK3 | SIK family kinase 3 | 0.0190005 |
| NTN4 | netrin 4 | 0.0186824 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0183292 |
| RPS17 | ribosomal protein S17 | 0.0181447 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0180899 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0180336 |
| B2M | beta-2-microglobulin | 0.0179776 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0179577 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0178344 |
| RPL31 | ribosomal protein L31 | 0.0178178 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0178047 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0173772 |
| OXSR1 | oxidative stress responsive 1 | 0.0173435 |
| DUSP16 | dual specificity phosphatase 16 | 0.0172515 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0172126 |
| DUSP5 | dual specificity phosphatase 5 | 0.0171867 |
| S100A11 | S100 calcium binding protein A11 | 0.0170205 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0169871 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0167387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.277531 |
| TXNRD1 | thioredoxin reductase 1 | -0.198053 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.184905 |
| ASPH | aspartate beta-hydroxylase | -0.141723 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0842724 |
| NDRG1 | N-myc downstream regulated 1 | -0.0780737 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0690896 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0685073 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0629827 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0620358 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0614991 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0575249 |
| MKI67 | marker of proliferation Ki-67 | -0.0566231 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0565913 |
| PKM | pyruvate kinase, muscle | -0.0560304 |
| CES1 | carboxylesterase 1 | -0.0549578 |
| EGFR | epidermal growth factor receptor | -0.0490343 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0488951 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0481691 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0467023 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0451539 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0438245 |
| TMEM165 | transmembrane protein 165 | -0.0437821 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0437384 |
| HDLBP | high density lipoprotein binding protein | -0.0434923 |
| NGLY1 | N-glycanase 1 | -0.0414387 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0410976 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0407154 |
| TPD52 | tumor protein D52 | -0.0394067 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0369727 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0369242 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0337969 |
| WASF2 | WAS protein family, member 2 | -0.0333575 |
| BBX | bobby sox homolog (Drosophila) | -0.0333351 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0331777 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0328787 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0322283 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320722 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0319792 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0317227 |
| CDCP1 | CUB domain containing protein 1 | -0.0311415 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0311113 |
| RUNX1 | runt-related transcription factor 1 | -0.0310088 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0302314 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0299882 |
| WDR45B | WD repeat domain 45B | -0.029767 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0296197 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0295354 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.029453 |
| TLK1 | tousled-like kinase 1 | -0.0286864 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0283845 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0283374 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0282477 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0281301 |
| SLMAP | sarcolemma associated protein | -0.0278615 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.027585 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0273962 |
| PAPOLA | poly(A) polymerase alpha | -0.0271002 |
| RPL4 | ribosomal protein L4 | -0.0270594 |
| FAM13A | family with sequence similarity 13, member A | -0.0267669 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0266394 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0259273 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0257379 |
| ECT2 | epithelial cell transforming 2 | -0.0257306 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.025595 |
| SMAD3 | SMAD family member 3 | -0.0254515 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0252853 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0250489 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0250127 |
| H1-0 | H1.0 linker histone | -0.0247678 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.024684 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0245391 |
| UBAC2 | UBA domain containing 2 | -0.0244526 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0237035 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0235971 |
| NABP1 | nucleic acid binding protein 1 | -0.023481 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0233938 |
| UVRAG | UV radiation resistance associated | -0.0233229 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0232523 |
| TKT | transketolase | -0.0231661 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0229723 |
| MYO1B | myosin IB | -0.0228201 |
| RLF | rearranged L-myc fusion | -0.0225862 |
| AHNAK | AHNAK nucleoprotein | -0.0225762 |
| ZNF292 | zinc finger protein 292 | -0.0225639 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0223595 |
| ACTG1 | actin gamma 1 | -0.0223201 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0223099 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0222554 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0219169 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0214696 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0212752 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0212675 |
| UBC | ubiquitin C | -0.0210328 |
| CDC73 | cell division cycle 73 | -0.0210091 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0208978 |
| NUP58 | nucleoporin 58 | -0.0208677 |
| GM2A | GM2 ganglioside activator | -0.0207932 |
| GPC6 | glypican 6 | -0.0206822 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0206203 |
