| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.109559 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0939082 |
| SMAD3 | SMAD family member 3 | 0.089656 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.086183 |
| PCBP2 | poly(rC) binding protein 2 | 0.0842047 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0556345 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0500841 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0499591 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0471065 |
| NAV2 | neuron navigator 2 | 0.044304 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0386032 |
| CD44 | CD44 molecule (Indian blood group) | 0.0383485 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0378888 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0368934 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0359794 |
| ZNF638 | zinc finger protein 638 | 0.0353214 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0351021 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0347062 |
| KYNU | kynureninase | 0.0346138 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0330433 |
| NTN4 | netrin 4 | 0.0323639 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0321769 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0303782 |
| SFTPA2 | surfactant protein A2 | 0.0296742 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0296512 |
| IL1R1 | interleukin 1 receptor, type I | 0.0294315 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0291902 |
| GOLGA4 | golgin A4 | 0.0285513 |
| KSR1 | kinase suppressor of ras 1 | 0.0281757 |
| TGM2 | transglutaminase 2 | 0.0281389 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0280053 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0270621 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0266542 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0264379 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0263678 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0262404 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0253572 |
| RHCG | Rh family, C glycoprotein | 0.0252441 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0237707 |
| ECE1 | endothelin converting enzyme 1 | 0.0235047 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.023444 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0234175 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0228003 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0227096 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0225689 |
| EZR | ezrin | 0.0221952 |
| USP47 | ubiquitin specific peptidase 47 | 0.021462 |
| ADD3 | adducin 3 (gamma) | 0.0212115 |
| ANGPTL4 | angiopoietin-like 4 | 0.0208691 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0208346 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0207747 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.020487 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0204167 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0202959 |
| IFI44L | interferon-induced protein 44-like | 0.0200956 |
| LAMA4 | laminin, alpha 4 | 0.0199035 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0196348 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0196058 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0193176 |
| RNF24 | ring finger protein 24 | 0.0191646 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0190704 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0189003 |
| VEGFA | vascular endothelial growth factor A | 0.0188928 |
| DUSP16 | dual specificity phosphatase 16 | 0.018544 |
| RARB | retinoic acid receptor, beta | 0.0185269 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0184039 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0182547 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0181651 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0181056 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0180596 |
| SYAP1 | synapse associated protein 1 | 0.0179303 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0178239 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.017542 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0174863 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0174529 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0171195 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0171112 |
| TPR | translocated promoter region, nuclear basket protein | 0.0169565 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0167494 |
| PALLD | palladin, cytoskeletal associated protein | 0.0161855 |
| CEP250 | centrosomal protein 250kDa | 0.0161698 |
| DUSP10 | dual specificity phosphatase 10 | 0.0159698 |
| OTUD7B | OTU deubiquitinase 7B | 0.0159582 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0157198 |
| UTRN | utrophin | 0.0157107 |
| PAPOLA | poly(A) polymerase alpha | 0.0155474 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0155198 |
| FBXO32 | F-box protein 32 | 0.0154873 |
| KIAA1217 | KIAA1217 | 0.0153202 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0152915 |
| ARRDC3 | arrestin domain containing 3 | 0.0152327 |
| APP | amyloid beta (A4) precursor protein | 0.0150008 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0149784 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0149445 |
| STK38L | serine/threonine kinase 38 like | 0.014927 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0149184 |
| YTHDC1 | YTH domain containing 1 | 0.0148487 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.014839 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0147824 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.216018 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.185136 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.154367 |
| CDH13 | cadherin 13 | -0.128357 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127899 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.116222 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.107753 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.107309 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.102518 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.102459 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0955323 |
| HMGA2 | high mobility group AT-hook 2 | -0.0928517 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0847981 |
| LOX | lysyl oxidase | -0.0841894 |
| MTSS1 | metastasis suppressor 1 | -0.0781775 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0766186 |
| TMSB10 | thymosin beta 10 | -0.0729993 |
| NRG1 | neuregulin 1 | -0.0726637 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0654615 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0646151 |
| MECOM | MDS1 and EVI1 complex locus | -0.0589942 |
| GPC6 | glypican 6 | -0.0574811 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0569378 |
| EFNA5 | ephrin-A5 | -0.0563568 |
| CDK14 | cyclin-dependent kinase 14 | -0.0545644 |
| OXR1 | oxidation resistance 1 | -0.0498395 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0494028 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0491831 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0489288 |
| MEF2A | myocyte enhancer factor 2A | -0.0489102 |
| DIAPH2 | diaphanous-related formin 2 | -0.0482587 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0471966 |
| ZNF804A | zinc finger protein 804A | -0.0466472 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0463573 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0417072 |
| STC1 | stanniocalcin 1 | -0.0413984 |
| DST | dystonin | -0.0410249 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.040788 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0406214 |
| USP34 | ubiquitin specific peptidase 34 | -0.0390827 |
| POTEF | POTE ankyrin domain family, member F | -0.0388194 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0384844 |
| RAI14 | retinoic acid induced 14 | -0.0381614 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.038158 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0375339 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0375233 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0374936 |
| EGR1 | early growth response 1 | -0.0371865 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0370499 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0368325 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0354286 |
| FAM20C | family with sequence similarity 20, member C | -0.0352009 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0343302 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0342135 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0336527 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0334783 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0333172 |
| CFAP20DC | CFAP20 domain containing | -0.0325963 |
| HDAC4 | histone deacetylase 4 | -0.0325528 |
| ATXN1 | ataxin 1 | -0.031788 |
| S100A6 | S100 calcium binding protein A6 | -0.0306974 |
| CUX1 | cut-like homeobox 1 | -0.0306031 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0305064 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0303014 |
| FBN1 | fibrillin 1 | -0.0302907 |
| CLMP | CXADR-like membrane protein | -0.0302793 |
| DNER | delta/notch-like EGF repeat containing | -0.0302532 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0293771 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0292465 |
| NAV3 | neuron navigator 3 | -0.0290666 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0290098 |
| ATG7 | autophagy related 7 | -0.0289492 |
| PRR16 | proline rich 16 | -0.0289189 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0288924 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0287312 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0285471 |
| NAV1 | neuron navigator 1 | -0.0284563 |
| VCL | vinculin | -0.0281975 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0281263 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0279831 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.027822 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0278178 |
| RAD51B | RAD51 paralog B | -0.0277248 |
| PRRX1 | paired related homeobox 1 | -0.0275772 |
| OSMR | oncostatin M receptor | -0.0268715 |
| TMEM165 | transmembrane protein 165 | -0.0267385 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265309 |
| NLK | nemo-like kinase | -0.0264984 |
| FTL | ferritin, light polypeptide | -0.0260407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0259149 |
| DTNA | dystrobrevin, alpha | -0.0255735 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0253107 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.025158 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0249329 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0246318 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0245993 |
| ENOSF1 | enolase superfamily member 1 | -0.0245231 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0242542 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0241629 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.024051 |
