| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.1672 |
| MT2A | metallothionein 2A | 0.112721 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0977377 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.077634 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0666443 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0658517 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0645271 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0593459 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0555187 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0552132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0528111 |
| FLNB | filamin B, beta | 0.0491601 |
| FMNL2 | formin-like 2 | 0.0470052 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0462434 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0440246 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0438011 |
| BRD2 | bromodomain containing 2 | 0.0436523 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0418653 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0415039 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0384062 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0381078 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0379416 |
| TOP1 | topoisomerase (DNA) I | 0.0377748 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0377304 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0373986 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0373985 |
| RPL37A | ribosomal protein L37a | 0.036766 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0367511 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0364448 |
| RPS3 | ribosomal protein S3 | 0.0363031 |
| COPA | coatomer protein complex, subunit alpha | 0.0353258 |
| TJP1 | tight junction protein 1 | 0.0348731 |
| RPS17 | ribosomal protein S17 | 0.0347095 |
| ACTN1 | actinin, alpha 1 | 0.0346818 |
| CTBP2 | C-terminal binding protein 2 | 0.0345335 |
| SFTPA2 | surfactant protein A2 | 0.0343643 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0342944 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0342071 |
| USP36 | ubiquitin specific peptidase 36 | 0.0336684 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331386 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0330903 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0330531 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0330187 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0330156 |
| FLNA | filamin A, alpha | 0.0326695 |
| NDRG1 | N-myc downstream regulated 1 | 0.0320969 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0319918 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0308827 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306777 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0302237 |
| SON | SON DNA binding protein | 0.0292409 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0289716 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284417 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0283623 |
| PCBP2 | poly(rC) binding protein 2 | 0.0283553 |
| FAM107B | family with sequence similarity 107, member B | 0.0283151 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0281503 |
| AATF | apoptosis antagonizing transcription factor | 0.0278666 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0272748 |
| ATP11A | ATPase, class VI, type 11A | 0.0270104 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0269343 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0267961 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0267536 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0265935 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0265238 |
| ATF4 | activating transcription factor 4 | 0.0263034 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.025931 |
| GOLGA4 | golgin A4 | 0.0259184 |
| RPS12 | ribosomal protein S12 | 0.0258342 |
| RCOR1 | REST corepressor 1 | 0.0256651 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0254534 |
| KIF5B | kinesin family member 5B | 0.0253411 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0251508 |
| TPI1 | triosephosphate isomerase 1 | 0.0250902 |
| MYO1E | myosin IE | 0.0247963 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0246862 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0245923 |
| GOLGB1 | golgin B1 | 0.0245803 |
| MSN | moesin | 0.0244162 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0242386 |
| BMP6 | bone morphogenetic protein 6 | 0.0241411 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0239778 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0239737 |
| WWOX | WW domain containing oxidoreductase | 0.0239653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0237792 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0236477 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0234778 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0230583 |
| CCNY | cyclin Y | 0.0230554 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0230205 |
| INTS6 | integrator complex subunit 6 | 0.0229151 |
| RPL31 | ribosomal protein L31 | 0.0226771 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0225061 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0223549 |
| MED13 | mediator complex subunit 13 | 0.0222779 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0222599 |
| MCL1 | myeloid cell leukemia 1 | 0.0219 |
| HLA-A | major histocompatibility complex, class I, A | 0.0218188 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0215745 |
| NLK | nemo-like kinase | 0.021503 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.433866 |
| TXNRD1 | thioredoxin reductase 1 | -0.161967 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.132501 |
| IGF2 | insulin-like growth factor 2 | -0.110076 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105131 |
| GRAMD1B | GRAM domain containing 1B | -0.1004 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0910359 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0900441 |
| ACTG1 | actin gamma 1 | -0.0897058 |
| FTL | ferritin, light polypeptide | -0.0864445 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0864083 |
| IER3 | immediate early response 3 | -0.0673456 |
| VIM | vimentin | -0.0557494 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0520039 |
| S100A10 | S100 calcium binding protein A10 | -0.0518551 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0514246 |
| POTEF | POTE ankyrin domain family, member F | -0.04915 |
| RPL19 | ribosomal protein L19 | -0.0451572 |
| TMEM123 | transmembrane protein 123 | -0.0448807 |
| CAVIN1 | caveolae associated protein 1 | -0.0442938 |
| RTN4 | reticulon 4 | -0.0432499 |
| PTMA | prothymosin, alpha | -0.042214 |
| HDAC9 | histone deacetylase 9 | -0.0412407 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0411753 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0410681 |
| S100A6 | S100 calcium binding protein A6 | -0.040966 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0403872 |
| PKM | pyruvate kinase, muscle | -0.0403869 |
| TPM4 | tropomyosin 4 | -0.0393658 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0388494 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0382346 |
| RAD21 | RAD21 homolog (S. pombe) | -0.037801 |
| SRGN | serglycin | -0.0372961 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0372947 |
| USP3 | ubiquitin specific peptidase 3 | -0.0367415 |
| AK1 | adenylate kinase 1 | -0.0346903 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0342172 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0336376 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0331716 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0330274 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0328782 |
| RPLP0 | ribosomal protein, large, P0 | -0.0328074 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0327506 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0326115 |
| RHOA | ras homolog family member A | -0.0325175 |
| BICC1 | BicC family RNA binding protein 1 | -0.0322606 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0322454 |
| RPL8 | ribosomal protein L8 | -0.0319046 |
| TUBB | tubulin, beta class I | -0.0315116 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0312912 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0309724 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0309186 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0307843 |
| CD99 | CD99 molecule | -0.030536 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0304766 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.030421 |
| RPL4 | ribosomal protein L4 | -0.0294645 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0294161 |
| GNAS | GNAS complex locus | -0.0293189 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0290971 |
| DEK | DEK proto-oncogene | -0.0290672 |
| PFDN2 | prefoldin subunit 2 | -0.0289636 |
| LOC112694756 | uncharaterized LOC112694756 | -0.028799 |
| THBS1 | thrombospondin 1 | -0.0286522 |
| RHEB | Ras homolog enriched in brain | -0.0285259 |
| PYGL | phosphorylase, glycogen, liver | -0.0282652 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0280838 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0279447 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0276099 |
| FGB | fibrinogen beta chain | -0.0275499 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.027366 |
| ANLN | anillin, actin binding protein | -0.0273647 |
| MORF4L1 | mortality factor 4 like 1 | -0.0273133 |
| ECT2 | epithelial cell transforming 2 | -0.0272943 |
| ANXA2 | annexin A2 | -0.0270349 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266859 |
| RPS5 | ribosomal protein S5 | -0.0266755 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0265361 |
| AHR | aryl hydrocarbon receptor | -0.0262185 |
| NEGR1 | neuronal growth regulator 1 | -0.0261285 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0261064 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0260534 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0260094 |
| CHN1 | chimerin 1 | -0.0259201 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0258229 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0257403 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0254403 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0254345 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0252466 |
| DST | dystonin | -0.0251271 |
| TAGLN2 | transgelin 2 | -0.0250383 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0249384 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0247592 |
| RPS21 | ribosomal protein S21 | -0.02469 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.0245688 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0244341 |
| UPP1 | uridine phosphorylase 1 | -0.0243907 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0243418 |
| FGG | fibrinogen gamma chain | -0.0241488 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0236926 |
