| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.129576 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.122053 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.112136 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.101714 |
| KRT17 | keratin 17, type I | 0.089816 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0792615 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0754247 |
| MT2A | metallothionein 2A | 0.0745225 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0720128 |
| TXNIP | thioredoxin interacting protein | 0.0665473 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0656151 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0656061 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.061712 |
| RPS19 | ribosomal protein S19 | 0.0594131 |
| LMO7 | LIM domain 7 | 0.0582615 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.057285 |
| MXD1 | MAX dimerization protein 1 | 0.0569867 |
| RPS12 | ribosomal protein S12 | 0.056564 |
| LAMB3 | laminin, beta 3 | 0.0562702 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0540984 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0540531 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0525291 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0519062 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.051404 |
| TOP1 | topoisomerase (DNA) I | 0.0506226 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0504097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0489517 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0484672 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.048253 |
| PCBP3 | poly(rC) binding protein 3 | 0.0480805 |
| MUC16 | mucin 16, cell surface associated | 0.0476042 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0475704 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.047278 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0469136 |
| RPL26 | ribosomal protein L26 | 0.0464281 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0456545 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.044644 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0445829 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0440762 |
| FLNB | filamin B, beta | 0.0436632 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0434855 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0433798 |
| RPL5 | ribosomal protein L5 | 0.0430001 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0427225 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0424106 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0421162 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.041285 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0410557 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0384417 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | 0.0383649 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0381 |
| DSPP | dentin sialophosphoprotein | 0.0376779 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.037294 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0371625 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0369776 |
| RPS27A | ribosomal protein S27a | 0.0366866 |
| COLEC11 | collectin sub-family member 11 | 0.0365715 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0364525 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0361594 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0361419 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.035651 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0355455 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.035366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0352818 |
| RPS3 | ribosomal protein S3 | 0.0352085 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0350925 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0349156 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0347489 |
| SMAD3 | SMAD family member 3 | 0.0346939 |
| RPS20 | ribosomal protein S20 | 0.0346104 |
| SNX25 | sorting nexin 25 | 0.034567 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0342573 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.034241 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.034077 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033948 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0339342 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.033151 |
| RPS17 | ribosomal protein S17 | 0.0329392 |
| KLF6 | Kruppel-like factor 6 | 0.0328484 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0324675 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0321145 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0315579 |
| ARRDC3 | arrestin domain containing 3 | 0.0315573 |
| ANXA1 | annexin A1 | 0.0314261 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0313077 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0311763 |
| FAT1 | FAT atypical cadherin 1 | 0.0311468 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0310389 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0305172 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0304146 |
| TPI1 | triosephosphate isomerase 1 | 0.0298647 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0298476 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.0298066 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0297153 |
| IRS2 | insulin receptor substrate 2 | 0.0295351 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0294636 |
| TFG | TRK-fused gene | 0.0294164 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0293817 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.029234 |
| EZR | ezrin | 0.0291977 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192587 |
| TXNRD1 | thioredoxin reductase 1 | -0.124864 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.107597 |
| ANXA2 | annexin A2 | -0.0946315 |
| GPC6 | glypican 6 | -0.0851087 |
| SMYD3 | SET and MYND domain containing 3 | -0.0842841 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0837433 |
| FN1 | fibronectin 1 | -0.0763592 |
| POTEF | POTE ankyrin domain family, member F | -0.0737484 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.069708 |
| LSAMP | limbic system-associated membrane protein | -0.0653534 |
| GSK3B | glycogen synthase kinase 3 beta | -0.064158 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0606583 |
| ASPH | aspartate beta-hydroxylase | -0.0596065 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.05809 |
| NF1 | neurofibromin 1 | -0.0572261 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0560394 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0554674 |
| DST | dystonin | -0.055275 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.054086 |
| TNPO1 | transportin 1 | -0.0518086 |
| OSMR | oncostatin M receptor | -0.0503762 |
| PTMA | prothymosin, alpha | -0.0483862 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0474508 |
| AK1 | adenylate kinase 1 | -0.0467546 |
| TMEM165 | transmembrane protein 165 | -0.0453895 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0436923 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0436131 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0435726 |
| MED13 | mediator complex subunit 13 | -0.0434044 |
| FTL | ferritin, light polypeptide | -0.0431369 |
| RTN4 | reticulon 4 | -0.0430431 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0429771 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0426291 |
| EGR1 | early growth response 1 | -0.0422013 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0420007 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0415849 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0413325 |
| RAD51B | RAD51 paralog B | -0.0412256 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0410888 |
| ENO1 | enolase 1, (alpha) | -0.0405292 |
| CUX1 | cut-like homeobox 1 | -0.0403861 |
| PRELID2 | PRELI domain containing 2 | -0.0397115 |
| NRG1 | neuregulin 1 | -0.0395873 |
| CCNI | cyclin I | -0.0395049 |
| JMJD1C | jumonji domain containing 1C | -0.0394226 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0393719 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0393008 |
| S100A10 | S100 calcium binding protein A10 | -0.0388984 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0381157 |
| RNF145 | ring finger protein 145 | -0.037985 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0379022 |
| RNF213 | ring finger protein 213 | -0.0377505 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0375076 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0373078 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0369543 |
| DTNA | dystrobrevin, alpha | -0.0368994 |
| KLHL24 | kelch-like family member 24 | -0.0368388 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0367219 |
| MYO1E | myosin IE | -0.0366537 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0364408 |
| MED13L | mediator complex subunit 13-like | -0.0360331 |
| SBF2 | SET binding factor 2 | -0.0356469 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0355983 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0353738 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0352442 |
| MSN | moesin | -0.0352037 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0349825 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0348344 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347624 |
| RAI14 | retinoic acid induced 14 | -0.0345742 |
| ZNF217 | zinc finger protein 217 | -0.0343967 |
| TPM4 | tropomyosin 4 | -0.0338251 |
| PDZD8 | PDZ domain containing 8 | -0.0337953 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0337059 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0335037 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0334544 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.033377 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0333127 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0327648 |
| EMP1 | epithelial membrane protein 1 | -0.0327159 |
| GRAMD1B | GRAM domain containing 1B | -0.0324947 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0324004 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0321346 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0321056 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0320235 |
| SH3D19 | SH3 domain containing 19 | -0.0316875 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0316463 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0315373 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0314779 |
| ZXDC | ZXD family zinc finger C | -0.0313401 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0311373 |
| BBX | bobby sox homolog (Drosophila) | -0.0310008 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0309615 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0308941 |
| ERBIN | erbb2 interacting protein | -0.0307841 |
| SPAG9 | sperm associated antigen 9 | -0.0304299 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0304052 |
| MORF4L2 | mortality factor 4 like 2 | -0.0302652 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.03013 |
