| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217196 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.173343 |
| YBX3 | Y box binding protein 3 | 0.101271 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0962013 |
| MCL1 | myeloid cell leukemia 1 | 0.0802073 |
| PCBP2 | poly(rC) binding protein 2 | 0.0645892 |
| TPI1 | triosephosphate isomerase 1 | 0.0608671 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0608294 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0583897 |
| TPM3 | tropomyosin 3 | 0.0546917 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0546543 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0532823 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0510612 |
| BRD2 | bromodomain containing 2 | 0.0492722 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0457696 |
| GRAMD1B | GRAM domain containing 1B | 0.0457493 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0453242 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0449765 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0431439 |
| HOMER1 | homer scaffolding protein 1 | 0.0425934 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0409463 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0405362 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.039737 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0397122 |
| INTS6 | integrator complex subunit 6 | 0.0396687 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0396043 |
| VCL | vinculin | 0.0385359 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0383769 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.038084 |
| CCDC200 | coiled-coil domain containing 200 | 0.0380347 |
| CCNL1 | cyclin L1 | 0.0380077 |
| JMJD1C | jumonji domain containing 1C | 0.037771 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0361451 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0361112 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0356036 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0347359 |
| PRELID2 | PRELI domain containing 2 | 0.0345068 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0337177 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0334369 |
| RPS3 | ribosomal protein S3 | 0.0324148 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0323554 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0314479 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0313217 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0300749 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0300709 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293852 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0293656 |
| TLN1 | talin 1 | 0.0284799 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284616 |
| SFTPA2 | surfactant protein A2 | 0.0283688 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0272254 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0263877 |
| MT2A | metallothionein 2A | 0.0261691 |
| KRT18 | keratin 18, type I | 0.0257501 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0248893 |
| MSN | moesin | 0.0248144 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0246076 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0245421 |
| TCIM | transcriptional and immune response regulator | 0.0243181 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0242901 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.023197 |
| PTMS | parathymosin | 0.0231163 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0230597 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0230495 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0229654 |
| YAP1 | Yes-associated protein 1 | 0.0229122 |
| RRM2 | ribonucleotide reductase M2 | 0.0229096 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0228837 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0228452 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0228383 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0228371 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0224109 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0220271 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0219893 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0219253 |
| CPNE1 | copine I | 0.0219092 |
| FERMT2 | fermitin family member 2 | 0.0218789 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0218028 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0212385 |
| RCOR1 | REST corepressor 1 | 0.0211838 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.021131 |
| RPL3 | ribosomal protein L3 | 0.0210879 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0209151 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0209143 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0207595 |
| CALD1 | caldesmon 1 | 0.0206114 |
| NEK10 | NIMA-related kinase 10 | 0.0204539 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0204488 |
| IPO7 | importin 7 | 0.0204148 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0203188 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0203144 |
| RPS7 | ribosomal protein S7 | 0.020138 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0200099 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0197386 |
| RPS18 | ribosomal protein S18 | 0.0196711 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0195922 |
| RBM39 | RNA binding motif protein 39 | 0.0194337 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0192737 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0191913 |
| PTMA | prothymosin, alpha | 0.0191616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.298455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.093688 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0681898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0518054 |
| RAD51B | RAD51 paralog B | -0.0487949 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.047621 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0474875 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0437191 |
| GNAS | GNAS complex locus | -0.040013 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0388191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0381858 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0379868 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0375795 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0369597 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0355116 |
| RNF213 | ring finger protein 213 | -0.0349704 |
| IER3 | immediate early response 3 | -0.0346595 |
| HMGA2 | high mobility group AT-hook 2 | -0.0342017 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0338833 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0337327 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0326249 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0325627 |
| BBX | bobby sox homolog (Drosophila) | -0.03172 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0314513 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0312113 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0311608 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309348 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0305577 |
| ZFR | zinc finger RNA binding protein | -0.0299804 |
| ACTG1 | actin gamma 1 | -0.0297567 |
| CAVIN1 | caveolae associated protein 1 | -0.0294314 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0287477 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0275157 |
| EGFR | epidermal growth factor receptor | -0.0268572 |
| PHF21A | PHD finger protein 21A | -0.0265985 |
| TLK1 | tousled-like kinase 1 | -0.0263214 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0259431 |
| CCND2 | cyclin D2 | -0.0254206 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0246556 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0245551 |
| SMAD3 | SMAD family member 3 | -0.0242778 |
| ZNF292 | zinc finger protein 292 | -0.0241593 |
| NF1 | neurofibromin 1 | -0.0241587 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0241299 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0241066 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0239973 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239727 |
| EHBP1 | EH domain binding protein 1 | -0.023964 |
| WASF2 | WAS protein family, member 2 | -0.0238202 |
| ENOSF1 | enolase superfamily member 1 | -0.0237715 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0236862 |
| MAP4 | microtubule-associated protein 4 | -0.0235416 |
| IGF2 | insulin-like growth factor 2 | -0.0233882 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0233324 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0229106 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0227164 |
| PTK2 | protein tyrosine kinase 2 | -0.0227159 |
| PHF20 | PHD finger protein 20 | -0.0227086 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0226578 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0225539 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0225324 |
| DENND5B | DENN/MADD domain containing 5B | -0.022448 |
| RPL6 | ribosomal protein L6 | -0.0223555 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0223028 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0222935 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0221483 |
| EPN2 | epsin 2 | -0.0218935 |
| TAOK1 | TAO kinase 1 | -0.0218007 |
| ATG7 | autophagy related 7 | -0.0217917 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0217315 |
| MMP12 | matrix metallopeptidase 12 | -0.0217308 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0213998 |
| RPL38 | ribosomal protein L38 | -0.0213777 |
| PARD3 | par-3 family cell polarity regulator | -0.0210828 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0210667 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0209166 |
| CCDC91 | coiled-coil domain containing 91 | -0.0207 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0206323 |
| RHBDD1 | rhomboid domain containing 1 | -0.0204774 |
| GOLT1B | golgi transport 1B | -0.0204507 |
| EXOC4 | exocyst complex component 4 | -0.0201442 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.020055 |
| USP34 | ubiquitin specific peptidase 34 | -0.0200098 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0199857 |
| FBXO11 | F-box protein 11 | -0.0199638 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0198921 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0194208 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0193959 |
| ANXA4 | annexin A4 | -0.0193818 |
| GLO1 | glyoxalase I | -0.0193693 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0190862 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0190674 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0190258 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0189432 |
| KIF13A | kinesin family member 13A | -0.0189427 |
| NUP155 | nucleoporin 155kDa | -0.0188713 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0186369 |
| TUT4 | terminal uridylyl transferase 4 | -0.0185453 |
| PGK1 | phosphoglycerate kinase 1 | -0.0184896 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.018468 |
