| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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131 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.146229 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.130699 |
| DST | dystonin | 0.129198 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.115665 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.114898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.111307 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.110988 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.101072 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0933505 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0911025 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0829191 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0814748 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.079205 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0785834 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.075772 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0684699 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0664368 |
| RBM39 | RNA binding motif protein 39 | 0.0660613 |
| ATXN1 | ataxin 1 | 0.0636568 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0635799 |
| RPS3 | ribosomal protein S3 | 0.0635665 |
| RORA | RAR-related orphan receptor A | 0.0628683 |
| NRG1 | neuregulin 1 | 0.0612804 |
| EZR | ezrin | 0.0604727 |
| HMGA2 | high mobility group AT-hook 2 | 0.0602023 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0600792 |
| ANXA2 | annexin A2 | 0.0494556 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0456949 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0450995 |
| RPL26 | ribosomal protein L26 | 0.0430393 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0421345 |
| FTL | ferritin, light polypeptide | 0.0378597 |
| ASPH | aspartate beta-hydroxylase | 0.0366286 |
| LMO7 | LIM domain 7 | 0.0361896 |
| RNF213 | ring finger protein 213 | 0.035676 |
| CDH13 | cadherin 13 | 0.0356757 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0346729 |
| CANX | calnexin | 0.034095 |
| SP100 | SP100 nuclear antigen | 0.0332367 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0326278 |
| CD2AP | CD2-associated protein | 0.0286017 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0259826 |
| VIM | vimentin | 0.0250603 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0226077 |
| RAB10 | RAB10, member RAS oncogene family | 0.0219959 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0196207 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0196041 |
| B2M | beta-2-microglobulin | 0.0192991 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0189487 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0185836 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0185286 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0148762 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0145778 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0131766 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0121056 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0116764 |
| EGFR | epidermal growth factor receptor | 0.0113087 |
| MYOF | myoferlin | 0.0107965 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00966549 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00885691 |
| TMSB10 | thymosin beta 10 | 0.00862356 |
| FLNB | filamin B, beta | 0.00719354 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00350009 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00282314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.148655 |
| PDE10A | phosphodiesterase 10A | -0.128436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.122617 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.118155 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.109768 |
| EXT1 | exostosin glycosyltransferase 1 | -0.103633 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.095517 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0848182 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0836682 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0804608 |
| FAM13A | family with sequence similarity 13, member A | -0.0790746 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0788586 |
| IGF2 | insulin-like growth factor 2 | -0.0778858 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0699046 |
| OGA | O-GlcNAcase | -0.0681224 |
| FMNL2 | formin-like 2 | -0.0666719 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0613826 |
| EFNA5 | ephrin-A5 | -0.057893 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0546977 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0532534 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0510869 |
| CCNI | cyclin I | -0.04894 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0472221 |
| SBF2 | SET binding factor 2 | -0.045672 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0445363 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0428245 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0414548 |
| SPAG9 | sperm associated antigen 9 | -0.0398282 |
| LAMA4 | laminin, alpha 4 | -0.0393515 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0380315 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0373334 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0362747 |
| TENM3 | teneurin transmembrane protein 3 | -0.0355362 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0340268 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0296602 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0293883 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0283744 |
| PTMA | prothymosin, alpha | -0.0283554 |
| SMYD3 | SET and MYND domain containing 3 | -0.0279663 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0266927 |
| FN1 | fibronectin 1 | -0.0263422 |
| ZNF292 | zinc finger protein 292 | -0.0250169 |
| INHBA | inhibin, beta A | -0.0244179 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.024104 |
| RPS6 | ribosomal protein S6 | -0.0231832 |
| GOLGA4 | golgin A4 | -0.0231414 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0228364 |
| RBM25 | RNA binding motif protein 25 | -0.0167196 |
| VCL | vinculin | -0.0164929 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0148439 |
| STC1 | stanniocalcin 1 | -0.0138338 |
| ANO6 | anoctamin 6 | -0.0128738 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0125806 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0109063 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0107612 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.010324 |
| MT2A | metallothionein 2A | -0.00903675 |
| NAV1 | neuron navigator 1 | -0.00867874 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00804206 |
| SLTM | SAFB-like, transcription modulator | -0.00655709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00623526 |
| RAD51B | RAD51 paralog B | -0.0048773 |
| NDRG1 | N-myc downstream regulated 1 | -0.00422272 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.00384919 |
| PRKCA | protein kinase C, alpha | -0.00357401 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00179009 |
