| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fluvoxamine (maleate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.239229 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0873903 |
| JMJD1C | jumonji domain containing 1C | 0.0766009 |
| TMSB10 | thymosin beta 10 | 0.0681885 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0645615 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0638993 |
| TJP1 | tight junction protein 1 | 0.0614866 |
| PCBP2 | poly(rC) binding protein 2 | 0.0574895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0564559 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0550829 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0496496 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0494621 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0484442 |
| XPO1 | exportin 1 | 0.0472519 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0467961 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0464587 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0462274 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.045974 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0445134 |
| MED13L | mediator complex subunit 13-like | 0.0441783 |
| COL5A2 | collagen, type V, alpha 2 | 0.0434328 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0433831 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0426134 |
| ENO1 | enolase 1, (alpha) | 0.0424573 |
| CALR | calreticulin | 0.0424325 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0400034 |
| RREB1 | ras responsive element binding protein 1 | 0.0382841 |
| ANK2 | ankyrin 2, neuronal | 0.0373677 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0359882 |
| SKIL | SKI-like proto-oncogene | 0.0356115 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0355922 |
| DENND4A | DENN/MADD domain containing 4A | 0.0349967 |
| SET | SET nuclear proto-oncogene | 0.0349821 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0349597 |
| PCDH18 | protocadherin 18 | 0.0349418 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0343072 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0337119 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0336974 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0328668 |
| ERBIN | erbb2 interacting protein | 0.03208 |
| RPL23 | ribosomal protein L23 | 0.031938 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0315184 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0313843 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.031092 |
| BRD2 | bromodomain containing 2 | 0.030822 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0307984 |
| CTBP2 | C-terminal binding protein 2 | 0.0303274 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0303216 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0301646 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0297162 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0296191 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0296077 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0295724 |
| BCOR | BCL6 corepressor | 0.0294678 |
| FGF13 | fibroblast growth factor 13 | 0.029393 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0292666 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292586 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0292529 |
| APP | amyloid beta (A4) precursor protein | 0.0291845 |
| KLHL24 | kelch-like family member 24 | 0.0291385 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.029135 |
| RPS27A | ribosomal protein S27a | 0.0285269 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.028385 |
| USP25 | ubiquitin specific peptidase 25 | 0.0283419 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274053 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0273303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0272718 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0268595 |
| SERTAD2 | SERTA domain containing 2 | 0.0267632 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0266809 |
| FOXP2 | forkhead box P2 | 0.0266203 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0261761 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0260708 |
| RPL3 | ribosomal protein L3 | 0.0259231 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0259204 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0258828 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0258152 |
| RCOR1 | REST corepressor 1 | 0.0258093 |
| RACK1 | receptor for activated C kinase 1 | 0.02555 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0252447 |
| GPHN | gephyrin | 0.0251115 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0250837 |
| CDH19 | cadherin 19, type 2 | 0.0249208 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.0249207 |
| MCL1 | myeloid cell leukemia 1 | 0.0247575 |
| SYT1 | synaptotagmin I | 0.0246945 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0245466 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.024326 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.024263 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0242476 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0241957 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0241751 |
| ZNF638 | zinc finger protein 638 | 0.024151 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0239913 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0239095 |
| REST | RE1-silencing transcription factor | 0.023827 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0237137 |
| CTSB | cathepsin B | 0.0236371 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0235779 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0234296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.112614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109914 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0898697 |
| VIM | vimentin | -0.087406 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0864855 |
| NTM | neurotrimin | -0.0839308 |
| GPC3 | glypican 3 | -0.0751043 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0705629 |
| CENPF | centromere protein F, 350/400kDa | -0.0690298 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0672596 |
| EMP1 | epithelial membrane protein 1 | -0.0630459 |
| RFPL4B | ret finger protein-like 4B | -0.0630422 |
| PEG10 | paternally expressed 10 | -0.0623819 |
| POTEF | POTE ankyrin domain family, member F | -0.0620243 |
| NOP58 | NOP58 ribonucleoprotein | -0.060909 |
| ACTG1 | actin gamma 1 | -0.0594132 |
| GNAS | GNAS complex locus | -0.05847 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0569415 |
| RPS16 | ribosomal protein S16 | -0.0568267 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0567256 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0543382 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0532755 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0528892 |
| SNX6 | sorting nexin 6 | -0.0520366 |
| RPS6 | ribosomal protein S6 | -0.0511968 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509106 |
| UPP1 | uridine phosphorylase 1 | -0.0507024 |
| MAP4 | microtubule-associated protein 4 | -0.0502773 |
| CLTC | clathrin, heavy chain (Hc) | -0.0497534 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0490696 |
| PLPP1 | phospholipid phosphatase 1 | -0.0488954 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0485851 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0479833 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0470188 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0469663 |
| RAI1 | retinoic acid induced 1 | -0.0469631 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0438307 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0429514 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0422526 |
| SPAG9 | sperm associated antigen 9 | -0.0422441 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0414606 |
| QKI | QKI, KH domain containing, RNA binding | -0.0413062 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0405404 |
| RPL6 | ribosomal protein L6 | -0.0402492 |
| LYST | lysosomal trafficking regulator | -0.03973 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0394773 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0393506 |
| ANXA2 | annexin A2 | -0.0393432 |
| THOC2 | THO complex 2 | -0.0388266 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0387847 |
| RPL34 | ribosomal protein L34 | -0.0382963 |
| DEK | DEK proto-oncogene | -0.0381021 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0376909 |
| ZNF292 | zinc finger protein 292 | -0.0367432 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0362284 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0361892 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0359427 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0354609 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0350734 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0350109 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0346591 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0345183 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0343119 |
| HDAC2 | histone deacetylase 2 | -0.0337731 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0336033 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0334117 |
| TUBA1B | tubulin, alpha 1b | -0.0333598 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0329863 |
| RPL11 | ribosomal protein L11 | -0.0328212 |
| TMEM123 | transmembrane protein 123 | -0.0327637 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0327253 |
| LYPLA1 | lysophospholipase I | -0.0322921 |
| UBQLN1 | ubiquilin 1 | -0.0318493 |
| HMGB1 | high mobility group box 1 | -0.0315445 |
| ZNF385D | zinc finger protein 385D | -0.0314361 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0312775 |
| EAPP | E2F-associated phosphoprotein | -0.0310895 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0307232 |
| TXNRD1 | thioredoxin reductase 1 | -0.0307161 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0306628 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0305981 |
| MEIS2 | Meis homeobox 2 | -0.0305758 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0302553 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.030161 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0296769 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0295682 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0292632 |
| ANXA5 | annexin A5 | -0.0291018 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0290841 |
| COG5 | component of oligomeric golgi complex 5 | -0.0289788 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0286887 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0284926 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0283149 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0282473 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0281975 |
| ACTN4 | actinin, alpha 4 | -0.0278968 |
| NEMF | nuclear export mediator factor | -0.0278375 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.02763 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0273039 |
| METAP2 | methionyl aminopeptidase 2 | -0.0272212 |
