| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0827931 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0695716 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0648806 |
| SFTPA2 | surfactant protein A2 | 0.0567446 |
| VCL | vinculin | 0.0546084 |
| ZFP36 | ZFP36 ring finger protein | 0.0517441 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0512845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0473885 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.046844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0453876 |
| MT2A | metallothionein 2A | 0.0448084 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0440399 |
| RPS12 | ribosomal protein S12 | 0.0435793 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0424801 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0407937 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0400286 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0396761 |
| YBX1 | Y box binding protein 1 | 0.0392897 |
| INTS6 | integrator complex subunit 6 | 0.0387554 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0386591 |
| PCBP2 | poly(rC) binding protein 2 | 0.0385052 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0384345 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0370303 |
| RPL23 | ribosomal protein L23 | 0.0353076 |
| BRD2 | bromodomain containing 2 | 0.0350127 |
| RPS3 | ribosomal protein S3 | 0.0336012 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0332584 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0330283 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0327221 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0322472 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0315037 |
| ASPH | aspartate beta-hydroxylase | 0.0309494 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0304736 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0298952 |
| CENPF | centromere protein F, 350/400kDa | 0.0296927 |
| RPS17 | ribosomal protein S17 | 0.0289278 |
| RPL12 | ribosomal protein L12 | 0.0283847 |
| MSN | moesin | 0.0282292 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0273536 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0272151 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0270717 |
| FTL | ferritin, light polypeptide | 0.0269161 |
| RPS2 | ribosomal protein S2 | 0.0267021 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0263708 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0263125 |
| B2M | beta-2-microglobulin | 0.0256525 |
| RPL11 | ribosomal protein L11 | 0.0251894 |
| RACK1 | receptor for activated C kinase 1 | 0.0251502 |
| NUP98 | nucleoporin 98kDa | 0.0248575 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248217 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024506 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0239159 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0237866 |
| CCDC88A | coiled-coil domain containing 88A | 0.0237587 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0231274 |
| TMSB10 | thymosin beta 10 | 0.0226103 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0222404 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0221122 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0219555 |
| PFN1 | profilin 1 | 0.0219242 |
| SON | SON DNA binding protein | 0.0216626 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0215645 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0213712 |
| RPL35A | ribosomal protein L35a | 0.0213373 |
| RPLP2 | ribosomal protein, large, P2 | 0.0207693 |
| CUL3 | cullin 3 | 0.02068 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0204253 |
| ATF6 | activating transcription factor 6 | 0.0203382 |
| HDAC9 | histone deacetylase 9 | 0.0203236 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0201839 |
| RPL3 | ribosomal protein L3 | 0.0200926 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0200801 |
| VEGFA | vascular endothelial growth factor A | 0.0199474 |
| ZNF638 | zinc finger protein 638 | 0.019877 |
| ITGAV | integrin, alpha V | 0.0198277 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0195289 |
| SATB2 | SATB homeobox 2 | 0.0193869 |
| TPM3 | tropomyosin 3 | 0.018674 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0183943 |
| ARRDC3 | arrestin domain containing 3 | 0.0183395 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0182644 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0182118 |
| RPS19 | ribosomal protein S19 | 0.0181424 |
| RRM2 | ribonucleotide reductase M2 | 0.0180403 |
| SET | SET nuclear proto-oncogene | 0.0180121 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0179267 |
| CTBP2 | C-terminal binding protein 2 | 0.0177838 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0177336 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0176701 |
| TPI1 | triosephosphate isomerase 1 | 0.0176329 |
| RPS8 | ribosomal protein S8 | 0.0176242 |
| RPL9 | ribosomal protein L9 | 0.0174857 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0173776 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0173271 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0170304 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0169745 |
| RPS18 | ribosomal protein S18 | 0.016576 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0165533 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0165389 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0164519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.129169 |
| VIM | vimentin | -0.116702 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104121 |
| AHNAK | AHNAK nucleoprotein | -0.0989091 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.097557 |
| PTMA | prothymosin, alpha | -0.0899146 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0755816 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0709739 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0670438 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0616612 |
| TMEM123 | transmembrane protein 123 | -0.0546399 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0532013 |
| CD44 | CD44 molecule (Indian blood group) | -0.0507758 |
| FBL | fibrillarin | -0.0475379 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0440998 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0438507 |
| ACTN4 | actinin, alpha 4 | -0.0423447 |
| CAVIN1 | caveolae associated protein 1 | -0.0404358 |
| ACTG1 | actin gamma 1 | -0.0391325 |
| ANXA2 | annexin A2 | -0.0387394 |
| CTSD | cathepsin D | -0.0383897 |
| SBF2 | SET binding factor 2 | -0.0375501 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0375123 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0351479 |
| AFAP1 | actin filament associated protein 1 | -0.0342046 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0338153 |
| FBXO17 | F-box protein 17 | -0.0291403 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0289468 |
| ZNF780B | zinc finger protein 780B | -0.0276355 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0271888 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0270181 |
| DST | dystonin | -0.0268678 |
| TMEM41B | transmembrane protein 41B | -0.0266405 |
| S100A6 | S100 calcium binding protein A6 | -0.0262702 |
| MAP4 | microtubule-associated protein 4 | -0.0260591 |
| EGFR | epidermal growth factor receptor | -0.0255909 |
| WASF2 | WAS protein family, member 2 | -0.0254009 |
| CANX | calnexin | -0.0245188 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0243415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0237271 |
| FRMD5 | FERM domain containing 5 | -0.0236836 |
| ANLN | anillin, actin binding protein | -0.0234114 |
| CD109 | CD109 molecule | -0.0232598 |
| BMERB1 | bMERB domain containing 1 | -0.0226856 |
| WDR45B | WD repeat domain 45B | -0.0224812 |
| CDCP1 | CUB domain containing protein 1 | -0.0222094 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0222083 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.021974 |
| RTN4 | reticulon 4 | -0.0218264 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0217302 |
| CALR | calreticulin | -0.0217214 |
| ATG7 | autophagy related 7 | -0.0212953 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211507 |
| HLA-B | major histocompatibility complex, class I, B | -0.0210311 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0209018 |
| RIN2 | Ras and Rab interactor 2 | -0.0204352 |
| DIAPH2 | diaphanous-related formin 2 | -0.0199453 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0190859 |
| R3HDM1 | R3H domain containing 1 | -0.0187099 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0184326 |
| PGK1 | phosphoglycerate kinase 1 | -0.0181101 |
| EHBP1 | EH domain binding protein 1 | -0.0179151 |
| HM13 | histocompatibility (minor) 13 | -0.0178652 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0177426 |
| RPS24 | ribosomal protein S24 | -0.0175178 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0173346 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.0172174 |
| TMEM263 | transmembrane protein 263 | -0.0171687 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0171189 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0170923 |
| ABLIM1 | actin binding LIM protein 1 | -0.0170348 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.016929 |
| MEF2A | myocyte enhancer factor 2A | -0.0169094 |
| TUBB | tubulin, beta class I | -0.0166831 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0164228 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0163829 |
| H1-0 | H1.0 linker histone | -0.0163085 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0162414 |
| TCF12 | transcription factor 12 | -0.0160207 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0160161 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0160038 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0158411 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0158277 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0156875 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0156379 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0155766 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0155299 |
| RGS20 | regulator of G-protein signaling 20 | -0.0154528 |
| CD47 | CD47 molecule | -0.0154481 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.015278 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0151797 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.015036 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0149667 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0147196 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0147053 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0146757 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0146541 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0145363 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0145186 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0144371 |
