| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126036 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0870969 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0855006 |
| LAMB3 | laminin, beta 3 | 0.0816806 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0764427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0761068 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0716964 |
| VEGFA | vascular endothelial growth factor A | 0.0635114 |
| SMAD3 | SMAD family member 3 | 0.0632772 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0624919 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0565749 |
| INTS6 | integrator complex subunit 6 | 0.0556752 |
| PCBP2 | poly(rC) binding protein 2 | 0.0548561 |
| TXNIP | thioredoxin interacting protein | 0.0547335 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0532015 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0492974 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0467828 |
| BRD2 | bromodomain containing 2 | 0.0449129 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0447276 |
| DSPP | dentin sialophosphoprotein | 0.0437273 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0416782 |
| TJP1 | tight junction protein 1 | 0.040352 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0394146 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.037816 |
| ARRDC3 | arrestin domain containing 3 | 0.037496 |
| NAV2 | neuron navigator 2 | 0.0369085 |
| DUSP5 | dual specificity phosphatase 5 | 0.03323 |
| TGM2 | transglutaminase 2 | 0.0327707 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.031721 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0311739 |
| RPS12 | ribosomal protein S12 | 0.0302804 |
| RPS18 | ribosomal protein S18 | 0.0301948 |
| OXSR1 | oxidative stress responsive 1 | 0.0298842 |
| IRS2 | insulin receptor substrate 2 | 0.0292417 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0291933 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0290318 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0289194 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0281339 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0280159 |
| FLNA | filamin A, alpha | 0.0273425 |
| TPM3 | tropomyosin 3 | 0.0273106 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272865 |
| PLEC | plectin | 0.0270224 |
| SFTPA2 | surfactant protein A2 | 0.0269666 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0268489 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.026671 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0264823 |
| MYO5B | myosin VB | 0.0264818 |
| RACK1 | receptor for activated C kinase 1 | 0.0263519 |
| RPS3 | ribosomal protein S3 | 0.0257234 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0257115 |
| CCNL1 | cyclin L1 | 0.0256895 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0254566 |
| RPS2 | ribosomal protein S2 | 0.0251229 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.025031 |
| MYO1E | myosin IE | 0.0244526 |
| PCDH1 | protocadherin 1 | 0.02436 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0243395 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0242861 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0242857 |
| CTBP2 | C-terminal binding protein 2 | 0.0239716 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0238718 |
| RPL3 | ribosomal protein L3 | 0.0236711 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0235555 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0233361 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.023187 |
| CLDN4 | claudin 4 | 0.0231595 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0231313 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0224707 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0223838 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0221196 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0219308 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0216349 |
| B2M | beta-2-microglobulin | 0.0213757 |
| WWC1 | WW and C2 domain containing 1 | 0.0213476 |
| THBS1 | thrombospondin 1 | 0.0212868 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0211882 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0210044 |
| YBX1 | Y box binding protein 1 | 0.020958 |
| RPL21 | ribosomal protein L21 | 0.0209398 |
| VMP1 | vacuole membrane protein 1 | 0.0208363 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0207424 |
| ANO6 | anoctamin 6 | 0.0207045 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0206801 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0205977 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0205849 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0204674 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0203891 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0202327 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0202046 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.02003 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0200139 |
| H1-10 | H1.10 linker histone | 0.0199974 |
| SET | SET nuclear proto-oncogene | 0.0196809 |
| RPS17 | ribosomal protein S17 | 0.0196581 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0195287 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0192205 |
| EGFR | epidermal growth factor receptor | 0.0190427 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0187923 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0186402 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280719 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.138574 |
| PTMA | prothymosin, alpha | -0.133788 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.109713 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.108187 |
| DSG2 | desmoglein 2 | -0.100683 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0954536 |
| CD2AP | CD2-associated protein | -0.0855182 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0820056 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0796278 |
| TMSB10 | thymosin beta 10 | -0.0764243 |
| KRT19 | keratin 19, type I | -0.0741304 |
| TMEM123 | transmembrane protein 123 | -0.0730952 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0688268 |
| TPM4 | tropomyosin 4 | -0.0682187 |
| ACTG1 | actin gamma 1 | -0.0678682 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0662351 |
| MUC4 | mucin 4, cell surface associated | -0.0630095 |
| EMP1 | epithelial membrane protein 1 | -0.0621724 |
| HLA-B | major histocompatibility complex, class I, B | -0.0606843 |
| ANXA2 | annexin A2 | -0.0580346 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0574465 |
| ANLN | anillin, actin binding protein | -0.0555032 |
| ASPH | aspartate beta-hydroxylase | -0.0521651 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0516095 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0508873 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0502531 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0500683 |
| S100A6 | S100 calcium binding protein A6 | -0.0498444 |
| HMGA1 | high mobility group AT-hook 1 | -0.0460409 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0454617 |
| LAMA4 | laminin, alpha 4 | -0.0449445 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0446767 |
| GNAS | GNAS complex locus | -0.0438382 |
| SYT14 | synaptotagmin XIV | -0.0433679 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0430032 |
| RPS24 | ribosomal protein S24 | -0.0428403 |
| LMO7 | LIM domain 7 | -0.0403836 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0389951 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0387057 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0386224 |
| HLA-E | major histocompatibility complex, class I, E | -0.03848 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0382827 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0373915 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0367741 |
| AHNAK | AHNAK nucleoprotein | -0.0367604 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0359064 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0357728 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0355226 |
| VCL | vinculin | -0.0353926 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0350682 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0349963 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0349197 |
| MEF2A | myocyte enhancer factor 2A | -0.0346213 |
| SULF2 | sulfatase 2 | -0.0338764 |
| RPL34 | ribosomal protein L34 | -0.0338624 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0337176 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0333633 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0331104 |
| PGK1 | phosphoglycerate kinase 1 | -0.0326267 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0320722 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0318852 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0317815 |
| RLF | rearranged L-myc fusion | -0.0317618 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.031653 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0309553 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0302194 |
| RIGI | RNA sensor RIG-I | -0.0300602 |
| DEK | DEK proto-oncogene | -0.0300419 |
| PLAT | plasminogen activator, tissue | -0.0298712 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0298564 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0296969 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0294318 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0289198 |
| ACTN4 | actinin, alpha 4 | -0.0288001 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0284691 |
| S100A10 | S100 calcium binding protein A10 | -0.02834 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0279417 |
| FN1 | fibronectin 1 | -0.0277726 |
| MUC20 | mucin 20, cell surface associated | -0.0276838 |
| RUNX1 | runt-related transcription factor 1 | -0.0275034 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0274938 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0267536 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.026662 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0265539 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0262513 |
| DAPK1 | death-associated protein kinase 1 | -0.0261093 |
| ITGB6 | integrin, beta 6 | -0.0260608 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.025971 |
| NRP1 | neuropilin 1 | -0.0258683 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.025812 |
| HLA-C | major histocompatibility complex, class I, C | -0.0257029 |
| WDR45B | WD repeat domain 45B | -0.0253256 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0251943 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0251496 |
| OGA | O-GlcNAcase | -0.0250438 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0249675 |
| TUBB | tubulin, beta class I | -0.024953 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0247996 |
| ARF1 | ADP-ribosylation factor 1 | -0.0247264 |
