| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.172437 |
| CD44 | CD44 molecule (Indian blood group) | 0.0738689 |
| AHNAK | AHNAK nucleoprotein | 0.0696227 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0669919 |
| COL5A3 | collagen, type V, alpha 3 | 0.0656771 |
| SMAD3 | SMAD family member 3 | 0.0652466 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0617013 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0590478 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0579199 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0548819 |
| ATP13A3 | ATPase type 13A3 | 0.0526631 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0491161 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0442924 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0437006 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0433997 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0423639 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0416605 |
| ANXA2 | annexin A2 | 0.0411247 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0410655 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0397746 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0394947 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0382262 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0365094 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0360167 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0337046 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0336958 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0333348 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0332781 |
| FMNL2 | formin-like 2 | 0.0331637 |
| KIAA1217 | KIAA1217 | 0.0321676 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0308962 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0305051 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0300867 |
| SVIL | supervillin | 0.0298182 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0294744 |
| ZNF638 | zinc finger protein 638 | 0.0291666 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.028511 |
| AFAP1 | actin filament associated protein 1 | 0.0278633 |
| CTSB | cathepsin B | 0.0274521 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0274306 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0272968 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.025895 |
| EMP1 | epithelial membrane protein 1 | 0.0258548 |
| TPM1 | tropomyosin 1 (alpha) | 0.025781 |
| FNDC3A | fibronectin type III domain containing 3A | 0.025721 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.025454 |
| TOP1 | topoisomerase (DNA) I | 0.0254474 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0251555 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0250647 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0250131 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0249374 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0248072 |
| COL1A1 | collagen, type I, alpha 1 | 0.0246875 |
| SMOX | spermine oxidase | 0.0246132 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0240267 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0238205 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0236271 |
| ITGAV | integrin, alpha V | 0.0233709 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0230708 |
| MLPH | melanophilin | 0.0230219 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0229895 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0227909 |
| PHF14 | PHD finger protein 14 | 0.0225956 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0224808 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0223912 |
| SYNJ2 | synaptojanin 2 | 0.0220567 |
| UTRN | utrophin | 0.0220256 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0215077 |
| ARRDC3 | arrestin domain containing 3 | 0.0214869 |
| AXL | AXL receptor tyrosine kinase | 0.021476 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0214233 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0212447 |
| MED13L | mediator complex subunit 13-like | 0.0212081 |
| TRIM56 | tripartite motif containing 56 | 0.0211823 |
| FHL2 | four and a half LIM domains 2 | 0.020943 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | 0.020921 |
| HLA-B | major histocompatibility complex, class I, B | 0.0208056 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0207948 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0206356 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0205861 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0204678 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0204217 |
| NF1 | neurofibromin 1 | 0.0203743 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0203584 |
| PDS5A | PDS5 cohesin associated factor A | 0.0202885 |
| RNF213 | ring finger protein 213 | 0.0201881 |
| ADAR | adenosine deaminase, RNA-specific | 0.0200463 |
| RANBP2 | RAN binding protein 2 | 0.0200014 |
| RBM5 | RNA binding motif protein 5 | 0.019976 |
| B2M | beta-2-microglobulin | 0.0198661 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0197253 |
| SERINC1 | serine incorporator 1 | 0.0196144 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0195733 |
| LYST | lysosomal trafficking regulator | 0.0191486 |
| CCNY | cyclin Y | 0.0191412 |
| IFI44 | interferon-induced protein 44 | 0.0191151 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0190946 |
| IFI44L | interferon-induced protein 44-like | 0.0189684 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0188583 |
| HLA-E | major histocompatibility complex, class I, E | 0.0188269 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.142301 |
| NDRG1 | N-myc downstream regulated 1 | -0.135084 |
| CDH13 | cadherin 13 | -0.127499 |
| VIM | vimentin | -0.0907351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0871811 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0850201 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0674854 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0616518 |
| EGR1 | early growth response 1 | -0.0596875 |
| TNS3 | tensin 3 | -0.0593096 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0582616 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.054167 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0511485 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.048283 |
| VEGFA | vascular endothelial growth factor A | -0.0476065 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0452535 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.042525 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0422373 |
| ATXN1 | ataxin 1 | -0.0409908 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0385542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0382373 |
| NAV1 | neuron navigator 1 | -0.0368756 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0366545 |
| SEC24A | SEC24 family member A | -0.0356392 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0353426 |
| COL5A1 | collagen, type V, alpha 1 | -0.0337617 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0333948 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0321535 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0321288 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.030936 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0306712 |
| LOX | lysyl oxidase | -0.0300143 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0299244 |
| PTK2 | protein tyrosine kinase 2 | -0.0299082 |
| RAD51B | RAD51 paralog B | -0.0292324 |
| MAP4 | microtubule-associated protein 4 | -0.0286475 |
| PKM | pyruvate kinase, muscle | -0.0283134 |
| BBX | bobby sox homolog (Drosophila) | -0.0280026 |
| CADM1 | cell adhesion molecule 1 | -0.0278945 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0278764 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0277894 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259568 |
| SRP54 | signal recognition particle 54kDa | -0.0257746 |
| TMSB10 | thymosin beta 10 | -0.0256655 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0255001 |
| IPO9 | importin 9 | -0.0253622 |
| NBEA | neurobeachin | -0.0251738 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0251482 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0250431 |
| POTEF | POTE ankyrin domain family, member F | -0.0248951 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0245831 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0243146 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0242788 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.024249 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0239269 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0237759 |
| COL5A2 | collagen, type V, alpha 2 | -0.0234095 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0233646 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0233181 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232614 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0232415 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0229752 |
| EGFR | epidermal growth factor receptor | -0.0229386 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0228097 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0227968 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0226436 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0223313 |
| RAI14 | retinoic acid induced 14 | -0.0221339 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0219881 |
| TMEM178B | transmembrane protein 178B | -0.0215643 |
| TTYH3 | tweety family member 3 | -0.0215072 |
| FTL | ferritin, light polypeptide | -0.0211245 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0208414 |
| DENND1A | DENN/MADD domain containing 1A | -0.0208145 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0206633 |
| GLIS3 | GLIS family zinc finger 3 | -0.0206546 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0205653 |
| FNIP1 | folliculin interacting protein 1 | -0.0204211 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0201217 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0200658 |
| MT2A | metallothionein 2A | -0.0200104 |
| MMP12 | matrix metallopeptidase 12 | -0.0199982 |
| FOXN3 | forkhead box N3 | -0.0199285 |
| PFN1 | profilin 1 | -0.0192928 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0191569 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0191431 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0187297 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0186667 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0186368 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0185834 |
| SON | SON DNA binding protein | -0.0184072 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0182718 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0182693 |
| OXR1 | oxidation resistance 1 | -0.0182292 |
| LOC112694756 | uncharaterized LOC112694756 | -0.018191 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0181903 |
| RTN4 | reticulon 4 | -0.0181703 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0181508 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0181402 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0180166 |
