| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fluvoxamine (maleate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fluvoxamine (maleate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.0472527 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0436033 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0399915 |
| INHBA | inhibin, beta A | 0.0391559 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0385799 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0376818 |
| MCL1 | myeloid cell leukemia 1 | 0.0345065 |
| STC1 | stanniocalcin 1 | 0.0333093 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0289147 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0281479 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0279747 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0274017 |
| ZFHX3 | zinc finger homeobox 3 | 0.0265182 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0255135 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0247557 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0242205 |
| NBEA | neurobeachin | 0.0236676 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0217126 |
| EGFR | epidermal growth factor receptor | 0.0216123 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0208208 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.0206006 |
| RORA | RAR-related orphan receptor A | 0.019247 |
| TOP1 | topoisomerase (DNA) I | 0.0191281 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0185561 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0183663 |
| PAEP | progestagen-associated endometrial protein | 0.0182238 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017995 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0174134 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0165633 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.016078 |
| HOMER1 | homer scaffolding protein 1 | 0.0160105 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0160059 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0158424 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0156911 |
| DUSP10 | dual specificity phosphatase 10 | 0.0154219 |
| SETX | senataxin | 0.0151768 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0149143 |
| CHGB | chromogranin B | 0.0148237 |
| TPP2 | tripeptidyl peptidase II | 0.0145603 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0145198 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0144754 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.014184 |
| EFNA5 | ephrin-A5 | 0.0141762 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.013955 |
| FAM13A | family with sequence similarity 13, member A | 0.0137352 |
| JUN | jun proto-oncogene | 0.013727 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0136495 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0135706 |
| VEGFA | vascular endothelial growth factor A | 0.013097 |
| EZR | ezrin | 0.0128759 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.012862 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0128359 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0128235 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0125704 |
| WLS | wntless Wnt ligand secretion mediator | 0.0123663 |
| TOX3 | TOX high mobility group box family member 3 | 0.0122463 |
| RPL3 | ribosomal protein L3 | 0.012206 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0121194 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | 0.0121135 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0120373 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0119593 |
| BRD2 | bromodomain containing 2 | 0.0118809 |
| ELMO1 | engulfment and cell motility 1 | 0.0117997 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0117991 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0116946 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0116901 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0116553 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0115801 |
| AHR | aryl hydrocarbon receptor | 0.0115216 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0115168 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0114804 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0114048 |
| LSAMP | limbic system-associated membrane protein | 0.0113996 |
| EPHA4 | EPH receptor A4 | 0.011167 |
| GOLGA3 | golgin A3 | 0.0111451 |
| IRS2 | insulin receptor substrate 2 | 0.0111086 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.0109681 |
| CRY1 | cryptochrome circadian clock 1 | 0.0109489 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0109006 |
| SLC8A3 | solute carrier family 8 (sodium/calcium exchanger), member 3 | 0.0107881 |
| SON | SON DNA binding protein | 0.0106929 |
| INTS6 | integrator complex subunit 6 | 0.0106815 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0106099 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.0105684 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0105633 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0104492 |
| ASPH | aspartate beta-hydroxylase | 0.0104217 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.010389 |
| TSPYL2 | TSPY-like 2 | 0.0103611 |
| RUNX1 | runt-related transcription factor 1 | 0.0102685 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0101826 |
| GPC6 | glypican 6 | 0.0101731 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0101368 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0101223 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0100073 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00994369 |
| PGM3 | phosphoglucomutase 3 | 0.00991687 |
| AQR | aquarius intron-binding spliceosomal factor | 0.00990448 |
| ATF6 | activating transcription factor 6 | 0.009856 |
| SVIL | supervillin | 0.00978474 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.154128 |
| CALCA | calcitonin-related polypeptide alpha | -0.142438 |
| TENM1 | teneurin transmembrane protein 1 | -0.120804 |
| CENPF | centromere protein F, 350/400kDa | -0.0906548 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0898943 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0851641 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0781795 |
| PEG10 | paternally expressed 10 | -0.0681454 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0624971 |
| RPS21 | ribosomal protein S21 | -0.0603475 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0586538 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0583926 |
| SYT1 | synaptotagmin I | -0.0555516 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0458497 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0454054 |
| ACTG1 | actin gamma 1 | -0.0433794 |
| MKI67 | marker of proliferation Ki-67 | -0.0430563 |
| RPS6 | ribosomal protein S6 | -0.0427447 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0418552 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0418479 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.041767 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0399046 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0387337 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0381572 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0379678 |
| S100A9 | S100 calcium binding protein A9 | -0.037418 |
| FGF14 | fibroblast growth factor 14 | -0.0372912 |
| GPC5 | glypican 5 | -0.0368332 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0360647 |
| RPL8 | ribosomal protein L8 | -0.0359046 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0356372 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0342819 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0336653 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0330382 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.032968 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0325852 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0325659 |
| FTL | ferritin, light polypeptide | -0.0313869 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0310396 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0306145 |
| CCDC88A | coiled-coil domain containing 88A | -0.0303927 |
| GNAS | GNAS complex locus | -0.0299476 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0298759 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0294861 |
| SNTG1 | syntrophin, gamma 1 | -0.0294247 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0290054 |
| PKM | pyruvate kinase, muscle | -0.0289609 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0288196 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.028325 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0281154 |
| RPS25 | ribosomal protein S25 | -0.0274842 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0273784 |
| POTEF | POTE ankyrin domain family, member F | -0.0271672 |
| RPL38 | ribosomal protein L38 | -0.0270524 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0266455 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0263953 |
| SYT4 | synaptotagmin IV | -0.0262678 |
| TXNRD1 | thioredoxin reductase 1 | -0.0258394 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0257202 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0252926 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0250295 |
| CHGA | chromogranin A | -0.0250239 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0244884 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0244397 |
| PFN1 | profilin 1 | -0.0241698 |
| TPX2 | TPX2, microtubule-associated | -0.0240405 |
| TUBA1B | tubulin, alpha 1b | -0.0239967 |
| RPL11 | ribosomal protein L11 | -0.023823 |
| NLGN1 | neuroligin 1 | -0.0234886 |
| RPLP0 | ribosomal protein, large, P0 | -0.0233852 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0233513 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0233468 |
| PDE10A | phosphodiesterase 10A | -0.02311 |
| RPL7 | ribosomal protein L7 | -0.0230437 |
| ZNF292 | zinc finger protein 292 | -0.0229831 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0229437 |
| RPS29 | ribosomal protein S29 | -0.0226859 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0225535 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0224515 |
| RPS23 | ribosomal protein S23 | -0.0223471 |
| RPL32 | ribosomal protein L32 | -0.0222983 |
| RPS8 | ribosomal protein S8 | -0.0221319 |
| RPL19 | ribosomal protein L19 | -0.0219119 |
| RIT2 | Ras-like without CAAX 2 | -0.0218783 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0217268 |
| RPS15 | ribosomal protein S15 | -0.0215064 |
| TMSB10 | thymosin beta 10 | -0.0212589 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0211625 |
| NFIA | nuclear factor I/A | -0.0209153 |
| RTN4 | reticulon 4 | -0.0206323 |
| AURKA | aurora kinase A | -0.0206242 |
| MAP1B | microtubule-associated protein 1B | -0.0206008 |
| FOXP1 | forkhead box P1 | -0.0205584 |
| CBX3 | chromobox homolog 3 | -0.0203827 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.020375 |
| TUBB | tubulin, beta class I | -0.0203134 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0202904 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0202885 |
| RPLP1 | ribosomal protein, large, P1 | -0.0202243 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0202186 |
